Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19

No benefit of hydroxychloroquine or chloroquine on the survival of COVID-19 patients found. For hydroxychloroquine, the confidence interval is compatible with increased mortality or negligibly reduced mortality. Findings... read more

Essentials of Perioperative Nursing

Essentials of Perioperative Nursing

Essentials of Perioperative Nursing, Sixth Edition is an essential reference for new perioperative nurses as well as experienced nurses who need a refresher. Succinct and easy to use, it addresses the basics associated with... read more

How Severe COVID-19 Infection is Changing ARDS Management

How Severe COVID-19 Infection is Changing ARDS Management

The COVID-19 pandemic has provided many intensivists (and some non-intensivists) several years' worth of severe ARDS management experience over the course of just a few months. While the challenges have, in places, been extreme,... read more

Pulse Wave Analysis to Estimate Cardiac Output

Pulse Wave Analysis to Estimate Cardiac Output

Cardiac output (CO)–guided therapy is a promising approach to hemodynamic management in high-risk patients having major surgery and in critically ill patients with circulatory shock. Pulmonary artery thermodilution remains... read more

Case Studies in Adult Intensive Care Medicine

Case Studies in Adult Intensive Care Medicine

Guiding FFICM and EDIC exam candidates through the intensive care medicine curriculum, this book provides 48 case studies mapped to eight key areas of study in the UK and European syllabuses. Cases include clinical vignettes,... read more

Letter Warns Against Clinical Role for Cardiac MRI in Asymptomatic COVID Patients

Letter Warns Against Clinical Role for Cardiac MRI in Asymptomatic COVID Patients

We are a group of clinicians, researchers and imaging specialists writing in response to recent publications and media coverage about myocarditis after COVID-19. We work in different areas such as public health, internal... read more

Principles Guiding Non Pandemic Critical Care Research During a Pandemic

Principles Guiding Non Pandemic Critical Care Research During a Pandemic

Deliberation about continuing non pandemic research should use objective, transparent criteria considering several aspects of the research process such as bedside and research staff safety, infection control, the informed... read more

Shorter Resident Shifts May Not Improve Patient Safety

Shorter Resident Shifts May Not Improve Patient Safety

Residents who worked schedules that eliminated extended shifts made a greater number of serious errors than those who worked schedules with shifts of 24 or more hours, a trial in the New England Journal of Medicine reported. The... read more

How AI is Reshaping Healthcare During COVID-19

How AI is Reshaping Healthcare During COVID-19

As the healthcare and pharmaceutical industries rush to tackle a wide range of COVID-19 challenges, from developing treatments and sourcing medical supplies to mitigating outbreaks and racing towards a vaccine, the use of... read more

Timing of Endoscopy for Acute Upper Gastrointestinal Bleeding

Timing of Endoscopy for Acute Upper Gastrointestinal Bleeding

In patients with high risk upper GI bleeding, who were treated with pre-endoscopy PPI and were not in persistent shock, an endoscopy performed at a median of 10 hours vs. a median of 25 hours post presentation did not reduce... read more

Right Heart Thrombus in Transit Diagnosed With Focused Cardiac Ultrasound

Right Heart Thrombus in Transit Diagnosed With Focused Cardiac Ultrasound

Pulmonary embolism (PE) is a potentially fatal entity that is frequently diagnosed in the emergency department (ED). Emergency physicians (EPs) routinely perform focused cardiac ultrasound (FOCUS) to support a prompt ED diagnosis... read more

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and ARDS

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and ARDS

In this preliminary study of patients with sepsis and ARDS, a 96-hour infusion of vitamin C compared with placebo did not significantly improve organ dysfunction scores or alter markers of inflammation and vascular injury.... read more

Physiologic Assessment: Variation in Fluid and Vasopressor Use in Shock

Physiologic Assessment: Variation in Fluid and Vasopressor Use in Shock

The decision whether to give more fluid during the management of shock can be somewhat provider-dependent. This multicenter prospective cohort study evaluated 1639 patients with hypotension requiring vasopressors. The... read more

Substituting Acetaminophen for Fentanyl Feasible in PCI for STEMI

Substituting Acetaminophen for Fentanyl Feasible in PCI for STEMI

In patients with STEMI given crushed ticagrelor before PCI, using IV acetaminophen instead of IV fentanyl as a painkiller did not increase pain levels or platelet reactivity and prevented delay of ticagrelor's effects, researchers... read more