Under the direction of Marc S. Sabatine, MD, MPH, Professor of Medicine, Harvard Medical School, Pocket Medicine provides the key information a clinician needs for the initial approach and management of... read more

Seems like a little thing, but I did this in response to a tweet by the National Rifle Association, asserting that doctors should “stay in our lane” instead of studying or making recommendations... read more

Survivors of intensive care are known to be at increased risk of developing longer-term psychopathology issues. We present a large UK multicentre study assessing the anxiety, depression and post-traumatic... read more

The Neonatal Resuscitation Program (NRP) is an educational program jointly sponsored by the American Academy of Pediatrics (AAP) and the American Heart Association (AHA). The course is designed to teach... read more

Changing Care to Improve Surgical Outcomes. In this mini-series of six podcasts sponsored by Abbott Nutrition, the DCRI’s Paul Wischmeyer, MD, EDIC, welcomes distinguished scientists and clinicians... read more

Sepsis is a leading cause of death and long-term disability in developed countries. A comprehensive report on the incidence, clinical characteristics, and evolving management of sepsis is important. Thus,... read more

Delirium is defined as an acute disorder of consciousness which can occur in up to 80% of mechanically ventilated ICU patients. This acute cognitive dysfunction is associated with prolonged hospital stay,... read more

The combination of PCT and CRP or presepsin alone improves the accuracy of diagnosis of neonatal sepsis. However, further studies are required to confirm these findings. A total of 28 studies enrolling... read more

Ventilator-associated pneumonia (VAP) remains a serious complication of mechanical ventilation (MV), and has an incidence between 2 and 16 episodes per 1000 ventilator-days, an attributable mortality of... read more

The Ceribell EEG System enabled rapid acquisition of electroencephalography (EEG) in patients at risk for non-convulsive seizures and aided clinicians in their evaluation of encephalopathic ICU patients.... read more

Urgent and drastic changes to the rules around medical devices, such as pacemakers, are needed to protect patients, according to the Royal College of Surgeons. It wants a register of every device in every... read more

In the recent issue of Critical Care Medicine, Law and colleagues published an evaluation of the impact of changes in Massachusetts state regulations mandating that nurse staffing levels on critical care... read more

As an MD-PhD candidate, now in the second year of a history of medicine PhD, I often reflect on the role of history in the medical school classroom and at the bedside. Medical history is a useful way to... read more

As little as 30 minutes of exposure to anesthetic and sedative agents may adversely affect the developing brain. Safe, humane management of critically ill infants requires the use of sedative agents, often... read more

Although acute liver failure (ALF) is a rare clinical presentation in the ED, it carries a high mortality, morbidity, and resource cost. Across the developing world, the underlying etiology is primarily... read more

Patients with refractory status epilepticus (RSE) treated with continuous intravenous anesthetic drugs (cIVADs) may benefit from early initiation of such therapy. wWhen cIVADs are applied in RSE, prescribing... read more

The optimum chest compression site (P_optimum) in children is debated: European Resuscitation Council recommends one finger breadth above the xiphisternal joint, whereas American Heart Association proposes... read more

Researchers have assessed the impact antibiotic therapy on short (hospital) and long-term (6 months) outcomes of ICU patients with severe community-acquired pneumonia. Community-acquired pneumonia (CAP)... read more

The risk of burnout in intensive care is high, there is a great need to look after ourselves and each other to enable us to effectively care for our patients and to be part of not only an effective team... read more

The use of ICU diaries in the PICU setting is feasible and perceived as beneficial by families of critically ill children. Future studies are needed to better understand if PICU diaries may objectively... read more