Tag: seizure

Upvote Story 9
Convulsive status epilepticus (CSE) is the most common life-threatening childhood neurological emergency. Despite this, there is a lack of high quality evidence supporting medication use after first line benzodiazepines, with current treatment protocols based solely on non-experimental evidence and expert opinion. The current standard of care, phenytoin, is only 60% effective, and associated with considerable adverse effects. A newer anti-convulsant, levetiracetam, can be given faster,... Read More | Comment
Upvote Story 6
The Ceribell EEG System enabled rapid acquisition of electroencephalography (EEG) in patients at risk for non-convulsive seizures and aided clinicians in their evaluation of encephalopathic ICU patients. The ease of use and speed of EEG acquisition and interpretation by EEG-untrained individuals has the potential to improve emergent clinical decision making by quickly detecting non-convulsive seizures in the ICU. Thirty-five cases of EEG sonification were performed.... Read More | Comment
Upvote Story 4
Patients with refractory status epilepticus (RSE) treated with continuous intravenous anesthetic drugs (cIVADs) may benefit from early initiation of such therapy. wWhen cIVADs are applied in RSE, prescribing them early may positively impact outcome, probably by shorter seizure duration and apparently mainly in those patients who do not have a severe RSE etiology dominating their prognosis. Fifty-three (68.8%) patients received cIVADs within the first 48... Read More | Comment
Upvote Story 4
Oral phenytoin loading can be achieved in a single dose, obviating the need for an IV while still achieving quick administration, adequate serum levels, and minimal side effects. Both the immediate release (suspension or chewable tablet) and extended release (phenytoin sodium ER capsule) products have been used successfully. IV loading does achieve quicker therapeutic level (3 hours), so there may still be a risk of... Read More | Comment
Upvote Story 5
For critically ill patients, a model comprising six variables can identify the probability of seizure, according to a study published online Oct. 9 in JAMA Neurology. Aaron F. Struck, M.D., from the University of Wisconsin in Madison, and colleagues conducted a prospective multicenter study using seizure risk factors from continuous electroencephalography (EEG) and clinical history to create a scoring system associated with the probability of... Read More | Comment