Measuring Cardiac Output at the Bedside
The purpose of this review is to review the importance of cardiac output (CO) or stroke volume (SV) measurement and to discuss the various methods (devices) used in determination of CO. Bedside cardiac output measurement... read more
Resuscitation Guided by Volume Responsiveness Does Not Reduce Mortality in Sepsis
The results of this systematic review and meta-analysis indicate that a volume responsiveness (VR) guided resuscitation strategy in sepsis patients confers no mortality benefit compared with usual care. The methods of... read more
Core Outcome Measures for Critical Care Ventilation Trials
The main objective for this study was to obtain international consensus on a set of core outcome measures that should be recorded in all clinical trials of interventions intended to modify the duration of ventilation for... read more
TPTD Techniques in the Hemodynamically Unstable Patient
Transpulmonary thermodilution (TPTD) devices invasively measure not only cardiac output but also several other hemodynamic variables estimating cardiac preload, cardiac preload, systolic function, the lung oedema and systolic... read more
Systematic Reviews and Meta-Analyses in Critical Care Research
This webinar provides an overview of the key steps involved in systematic reviews and meta-analysis for those interested in using these approaches in their own research. As the volume of published research in critical... read more
Risk Factors for Avoidable Transfer to a Pediatric Trauma Center Among Patients Age Two Years and Older
Among injured children age two years and older, those with minor head injuries were at greatest risk for avoidable transfer. Many were transferred because of a perceived need for evaluation by a pediatric neurosurgeon. Future... read more
Worse outcomes with video laryngoscopy in ICU
When used in intensive care units, video laryngoscopy did not improve the chances of successful intubation on the first try, compared with direct laryngoscopy, and was associated with a significantly higher risk of severe... read more
The negative effect of initial high-dose methylprednisolone and tapering regimen for ARDS
The efficacy of corticosteroid use in acute respiratory distress syndrome (ARDS) remains controversial. Generally, short-term high-dose corticosteroid therapy is considered to be ineffective in ARDS. On the other hand, low-dose,... read more
Continuous or Intermittent Feeding: Pros and Cons
Although there are limited studies investigating the safety and efficacy of an intermittent rather than continuous feeding regimen in critically ill adults, there are several theoretical advantages. Further studies should... read more
Sex-specific Differences in Survival After Out-of-hospital Cardiac Arrest
This nationwide, population-based observational study in Japan included 386,535 adult patients aged ≥ 18 years with out-of-hospital cardiac arrest (OHCA). In all these patients, resuscitation was attempted by EMS personnel... read more
Long-term Health Consequences of Under- and Over-feeding in PICU
Energy is essential for the treatment and recovery of children admitted to Pediatric Intensive Care Units (PICU). There are significant immediate and long-term health consequences of both under- and over-feeding in this population.... read more
Predictive Utility of DNI in Patients with MOF After Severe Traumatic Injury
Post-injury multiple organ failure (MOF) is the result of a systemic uncontrolled inflammatory response and it is the one of leading cause of late post-injury mortality. Delta neutrophil index (DNI) may serve useful marker... read more
Terlipressin for Septic Shock Patients
Catecholamines are commonly used in septic shock but face limitations of their hypo-responsiveness and adverse events due to high dose. Terlipressin is a synthetic vasopressin analog with greater selectivity for the V1-receptor.... read more
The Poor Man’s Tox Screen: ECG Findings in the Acute Overdose
In the middle of a busy ED shift the tech runs up to you with an ECG. Just prior to signing the top "No STEMI" you think: "wait, why do the QRS complexes look like that?" You walk back to triage with the tech to see a... read more
Time-Course of Clinical Physiologic Variables in ARDS Patients Undergoing ECMO
In patients undergoing extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS), it is unknown which clinical physiologic variables should be monitored to follow the evolution of lung injury... read more
A Multidisciplinary Idea to STEP UP Resuscitation Effectiveness
Non-technical skills and human factors are increasingly recognized as critical ingredients in the success or failure of acute care delivery in a number of high stakes clinical domains. This is reflected in the evolution of... read more
Clustering Algorithms Usage in Critical Care Research Unravel Patient Heterogeneity
Critically ill patients constitute the most heterogeneous population in the hospital, with the highest rates of acute and chronic multi-morbidity. Daily, two critically ill patients are admitted to the ICU with the same... read more
Few Ideas on How Nurses Can Recover After Difficult Shifts
Most medical professionals agree that a nursing career can be constantly stressful. It comes with the territory of caring for those who are ill and injured. On an average day, well-trained nurses are more than capable of... read more
Hemodynamic Monitoring in the ECMO Patient
Hemodynamic monitoring in extracorporeal membrane oxygenation (ECMO) patients requires familiarity with the underlying pathophysiology and circulatory mechanics of extracorporeal flow. This review discusses the various monitoring... read more
Clinical Impact and Assessment Tools Capable of Identifying Delirium in Cardiac Arrest Survivors
This review aims to describe the clinical impact and assessment tools capable of identifying delirium in cardiac arrest survivors and providing strategies aimed at preventing and treating delirium. Patient factors leading... read more
State-Mandated Protocolized Sepsis Care Associated with Decrease in Sepsis Mortality
Beginning in 2013, New York State implemented regulations mandating that hospitals implement evidence-based protocols for sepsis management, as well as report data on clinical outcomes to the state government. This study... read more
Age and Decisions to Limit Life Support for Patients with ALI
The purpose of this study was to estimate the association between patient age and the rate of new limitations in the use of life support, independent of daily organ dysfunction status, following acute lung injury (ALI) onset. 490... read more
