Diagnostic error increases mortality and length of hospital stay in patients presenting through the emergency room
Diagnostic errors occur frequently, especially in the emergency room. Estimates about the consequences of diagnostic error vary widely and little is known about the factors predicting error. Our objectives thus was to determine... read more
Where Night Is Day: The World of the ICU
Where Night Is Day is a nonfiction narrative grounded in the day-by-day, hour-by-hour rhythms of an ICU in a teaching hospital in the heart of New Mexico. It takes place over a thirteen-week period, the time of the average... read more
Mechanical Ventilation Enhances Extrapulmonary Sepsis-induced Lung Injury
These data show for the first time that otherwise noninjurious mechanical ventilation can exacerbate acute lung injury (ALI) due to extrapulmonary sepsis underscoring a potential interactive contribution of common events... read more
Characteristics, Management, and In-hospital Mortality Among Patients with Severe Sepsis in ICU in Japan
Sepsis is a leading cause of death and long-term disability in developed countries. A comprehensive report on the incidence, clinical characteristics, and evolving management of sepsis is important. Thus, this study aimed... read more
Prediction of ICU Delirium
The predictive models evaluated in this study demonstrated moderate to good discriminative ability to predict ICU patients' risk of developing delirium. Models calculated at 24-hours post-ICU admission appear to be more accurate... read more
Early Sepsis Screening in the Emergency Department
This single-center retrospective analysis shows promising results with NEWS as a screening tool primarily because it can be done at triage and does not require any laboratory evaluation. This study adds to the current knowledge... read more
How can we make ICU rehabilitation easier for patients and relatives?
Zoe van Willigen is a Physiotherapist in Critical Care at University Hospital Southampton NHS Foundation Trust. Her study aims to explore patients' and relatives' experiences of ICU rehabilitation (being mobilised out of... read more
Relationship of at Admission Lactate, Unmeasured Anions, and Chloride to the Outcome of Critically Ill Patients
Four thousand nine hundred one patients were admitted throughout the study period; 1,609 met criteria for metabolic acidosis and 145 had normal acid-base values. The association between at admission lactate, unmeasured anions,... read more
Combined Biomarkers Predict Acute Mortality Among Critically Ill Patients With Suspected Sepsis
Combined biomarkers predict risk for 14-day and total mortality among subjects with suspected sepsis. Serum amyloid P and tissue plasminogen activator demonstrated the best discriminatory ability in this cohort. Fourteen-day... read more
Sedation Practice in ECMO-Treated Patients with ARDS
Our objective was to characterize sedation management in adult patients with severe respiratory distress syndrome (ARDS) treated with venovenous extracorporeal membrane oxygenation (VV-ECMO). We conducted a retrospective... read more
Metabolic Acidosis: A Guide to Clinical Assessment and Management
This timely volume provides an overview to the causes, effects on systems and clinical approaches of metabolic acidosis. Beginning with a basic understanding of the physiology, pathophysiology and development of this disease,... read more
Noninvasive ventilation for avoidance of reintubation in patients with various cough strength
The aim of this study was to assess whether prophylactic noninvasive ventilation (NIV) would benefit patients with various cough strengths.... read more
Unaccountable: What Hospitals Won’t Tell You and How Transparency Can Revolutionize Health Care
Dr. Marty Makary is co-developer of the life-saving checklist outlined in Atul Gawande's bestseller The Checklist Manifesto. A Johns Hopkins surgeon and professor of public health, he can testify to the amazing power of modern... read more
The Effect of Adhesive Tape vs. Endotracheal Tube Fastener in Critically Ill Adults
The optimal securement method of endotracheal tubes is unknown but should prevent dislodgement while minimizing complications. The use of an endotracheal tube fastener might reduce complications among critically ill adults... read more
From In Shock to True Connection with Our Patients
If you work in healthcare and haven't read the book "In Shock: My Journey from Death to Recovery and the Redemptive Power of Hope" I really hope you will. In the meantime listen to intensivist and best-selling author Dr Rana... read more
Mapping Sources of Noise in an ICU
Excessive noise in hospitals adversely affects patients' sleep and recovery, causes stress and fatigue in staff and hampers communication. The World Health Organization suggests sound levels should be limited to 35 decibels.... read more
A Positive Fluid Balance is an Independent Prognostic Factor in Patients with Sepsis
Intravenous fluid administration is an essential component of sepsis management, but a positive fluid balance has been associated with worse prognosis. We analyzed whether a positive fluid balance and its persistence over... read more
Evaluation of Medetomidine-ketamine and Atipamezole for Reversible Anesthesia of Free-ranging Gray Wolves
Twenty-eight anesthetic events were carried out on 24 free-ranging Scandinavian gray wolves (Canis lupus) by darting from a helicopter with 5 mg medetomidine and 250 mg ketamine during winter in 2002 and 2003. Mean±SD doses... read more
Anticoagulant Reversal
Ranjit Deshpande, MD, and Mark D. Cipolle, MD, PhD, FCCM, discuss Dr. Cipolle's talk from the 48th Critical Care Congress on what's new in anticoagulant reversal. Tune in to hear about the hottest topics and current research.... read more
ED Door-to-Antibiotic Time and Long-term Mortality in Sepsis
Delays in ED antibiotic initiation time are associated with clinically important increases in long-term, risk-adjusted sepsis mortality. This study investigated the association of door-to-antibiotic time with long-term mortality... read more
PERFECT Protocol: Volume-based Feeding in Ventilated Adults
Underfeeding in critical illness is common and associated with poor outcomes. Researchers in the UK designed a before-and-after study to evaluate the safety, efficacy and clinical outcomes associated with volume-based feeding... read more
This Is Going to Hurt: Secret Diaries of a Junior Doctor
Welcome to 97-hour weeks. Welcome to life and death decisions. Welcome to a constant tsunami of bodily fluids. Welcome to earning less than the hospital parking meter. Wave goodbye to your friends and relationships. Welcome... read more
