Prevention of VAP: Effects of a National multi-modal Approach in Spain

This large, prospective multi-centre study demonstrates that a national approach (incorporating a care bundle, education cascade, and clinical governance process) for Ventilator-associated pneumonia (VAP) prevention is feasible... read more

Hemodynamic Response After Rapid Sequence Induction With Ketamine in Out-of-Hospital Patients at Risk of Shock as Defined by the Shock Index

After ketamine induction, high shock index patients exhibited blunted hypertensive responses and more frequent hypotension, whereas low shock index patients had sustained increases in pulse rate and SBP. One hundred twelve... read more

Guidelines for the Diagnosis and Management of CIRCI in Critically Ill Patients

This part II of the guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients is related to acute illnesses that may be complicated by CIRCI. We... read more

Human limb skeletal muscle wasting and architectural remodeling during five to ten days intubation and ventilation in critical care

Using ultrasound, we have been able to demonstrate that muscle thickness and architecture of vastus lateralis undergo rapid changes during the early phase of admission to a critical care environment. Muscle loss in critically... read more

Airway Management Techniques during Massive Regurgitation, Emesis, or Bleeding

Friend to the show, Jim DuCanto has been obsessed with SALAD. Not the leafy greens delicately touched with a tart emulsion, but with Suction Assisted Laryngoscopy and Airway Decontamination (SALAD). Jim DuCanto, MD is an... read more

ECMO – How can I make the best referral?

Extracorporeal membrane oxygenation or ECMO is one of those treatments we sometimes need to think about with our very sick patients. I recently had to make a referral to my local centre and doing so made me wonder what it... read more

Petition to Retire the Surviving Sepsis Campaign Guidelines

Concern regarding the Surviving Sepsis Campaign (SSC) guidelines dates back to their inception. Guideline development was sponsored by Eli Lilly and Edwards Life Sciences as part of a commercial marketing campaign. Throughout... read more

Limiting Sedation for Patients with ARDS

Current evidence supports the use of protocol-based, light-sedation strategies in critically ill patients with ARDS. Further research into sedation management specifically in ARDS populations is needed. Deep sedation strategies... read more

The Real Doctor Will See You Shortly: A Physician’s First Year

In medical school, Matt McCarthy dreamed of being a different kind of doctor—the sort of mythical, unflappable physician who could reach unreachable patients. But when a new admission to the critical care unit almost died... read more

The Real Doctor Will See You Shortly: A Physician’s First Year

Ketamine Alters Hippocampal Cell Proliferation and Improves Learning in Mice after TBI

Ketamine alters hippocampal cell proliferation after traumatic brain injury (TBI). Surprisingly, these changes were associated with improvement in a neurogenesis-related behavioral recall task, suggesting a possible benefit... read more

Advances in Critical Care Management of Patients Undergoing Cardiac Surgery

Cardiac surgery has been evolving to include minimally invasive, hybrid and transcatheter techniques. Increas‑ing patient age and medical complexity means that critical care management needs to adapt and evolve. Recent... read more

Mechanical Ventilation: Physiological and Clinical Applications

Known for its simple explanations and in-depth coverage of patient-ventilator management, this evidence-based text walks readers through the most fundamental and advanced concepts surrounding mechanical ventilation and guides... read more

Mechanical Ventilation: Physiological and Clinical Applications

A Fundamentals Train-the-Trainer Approach to Building Pediatric Critical Care Expertise in the Developing World

Pediatric Fundamental Critical Care Support (PFCCS) is an educational tool for training non-intensivists, nurses, and critical care practitioners in diverse health-care settings to deal with the acute deterioration of pediatric... read more

The A1 Sedation Package: Better Care for Intubated Patients

You are called to the scene of a 56-year-old male found unresponsive in his garage workshop. Upon examining him you find him minimally responsive to painful stimulus, moaning and groaning. His family tells you he has high... read more

Trauma Room Two

In every hospital emergency department there is a room reserved for trauma. It is a place where life and death are separated by the thinnest of margins. A place where some families celebrate the most improbable of victories... read more

Trauma Room Two

Pre-hospital advanced airway management by anaesthetist and nurse anaesthetist critical care teams

When performed by experienced physician anaesthetists and nurse anaesthetists, pre-hospital tracheal intubation was completed rapidly with high success rates and a low incidence of complications. The critical care teams attended... read more

Techniques for the Difficult Airway

A systematic approach to intubation that emphasizes planning and teamwork can reduce intubation complications. Early use of an EGA or cricothyroidotomy may reduce complications when oxygenation is inadequate. Use of a gum... read more

Sophia Observation Withdrawal Symptoms-Pediatric Delirium Scale

The SOS-PD scale shows promising validity for early screening of Pediatric Delirium (PD). Further evidence should be obtained from an international multicentre study. A total of 2088 assessments were performed in 146 children... read more

Drowned: Nurses Under Water

Nurses are expensive. We are the largest professional workforce in healthcare, and with over 3.1 million professional nurses in the country, it appears that we are large in number but small as a priority. Nurses are overworked.... read more

Acute kidney injury common in children, young adults in ICU

Among children and young adults admitted to intensive care, as many as 1 in 4 may have acute kidney injury and 1 in 10 may have severe acute kidney injury. Acute kidney injury is common in children and young adults admitted... read more

A Pilot Study of Eye-Tracking Devices in ICU

Eye-tracking devices have been suggested as a means of improving communication and psychosocial status among patients in the intensive care unit (ICU). This study was undertaken to explore the psychosocial impact and communication... read more

The Next Generation of Doctors May be Learning Bad Habits at Teaching Hospitals with Many Safety Violations

Teaching hospitals like Jackson South, located in metro Miami, are where physician trainees get practice treating patients. They prepare the next generation of doctors, and they have a reputation as places of cutting-edge... read more