Fluid Personalization and Vasopressor Decisions in Early Sepsis Management
In this randomized vignette survey study of US critical care clinicians, we found that fluid volume already received was associated with the largest changes in decisions to administer additional fluids or initiate vasopressors... read more
Traumatic Major Hemorrhage in a Tertiary Trauma Center
Major traumatic hemorrhage is potentially preventable with rapid hemorrhage control and improved resuscitation techniques. The time from injury to hospital, resuscitation, diagnosis, and definitive bleeding control should... read more
Scientific Study Validates Usability of Post-ICU Digital Diary for Families of ICU Patients
In a groundbreaking pilot study, "The usability of a digital diary from the perspectives of intensive care patients’ relatives", researchers have unequivocally confirmed the practicality and effectiveness of Post-ICU for... read more
AKI Risk Factors in ICU Patients Using Colistin
Colistin, an antibiotic of polymyxin group, has recently been increasingly used in the treatment of multidrug resistant gram-negative bacteria. However, it has serious adverse effects such as acute kidney injury (AKI). We... read more
Anticipating the Future of the COVID-19 Pandemic
The initial instance of a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection was observed in December 2019 in the city of Wuhan, China. Subsequently, the virus disseminated expeditiously across the globe,... read more
COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients
This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the COVID-19 pandemic, and offers practical information on how to manage them. Older... read more
VTE in Critically Ill Adult Patients with Hematologic Malignancy
Among patients with hematologic malignancy, critical illness and certain baseline characteristics were associated with a higher incidence of venous thromboembolism (VTE). Among 76,803 eligible patients (mean age 67 years... read more
Omadacycline Treatment of Severe Pneumonia Complicated with ARDS During COVID-19
Metagenomic next-generation sequencing (mNGS) has a significant value in the diagnosis of Chlamydia psittaci infection. Timely treatment of omadacycline can improve prognosis and provide a promising new option for the treatment... read more
Sepsis Management: PIRO and MODS
This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent... read more
Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU
We analyzed unvaccinated critically ill ICU patients with COVID-19 and interpreted their demographics, clinical characteristics, comorbidities, and laboratory data upon ICU admission for a better understanding of their impact... read more
Haloperidol vs. Placebo in ICU Patients with Delirium
We assessed long-term outcomes in acutely admitted adult patients with delirium treated in intensive care unit (ICU) with haloperidol versus placebo. In acutely admitted adult ICU patients with delirium, haloperidol treatment... read more
Extracorporeal Life Support for Adults
This book presents a concise, evidence-based review of extracorporeal life support (ECLS) for adult diseases. It describes the use of ECLS with patients who are experiencing severe hypoxemic respiratory failure (ARDS and... read more
10 Reasons for Pharmacy Professionals Presence in the ICU
The momentum exists for establishing and expanding ICU pharmacy practice throughout Europe. A first step should be a White Paper, describing the roles and key priorities for ICU pharmacy professionals. Education should... read more
Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia
Delivery of prehospital emergency anesthesia (PHEA) to seriously injured trauma patients risks hemodynamic fluctuation. In adult trauma patients undergoing PHEA, 11.9% of patients experienced post-PHEA critical hypertension.... read more