Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock

Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock

Worse global longitudinal strain (GLS) (less negative) values are associated with higher mortality in patients with severe sepsis or septic shock, while such association is not valid for left ventricular ejection fraction... read more

Ethical Dilemmas in Pediatrics

Ethical Dilemmas in Pediatrics

Children in precarious health present particular problems for healthcare professionals because of their intimate relation to their family, and because of the family's need to provide major long-term source of support and... read more

Pooled Analysis of Higher vs Lower Blood Pressure Targets for Vasopressor Therapy Septic and Vasodilatory Shock

Pooled Analysis of Higher vs Lower Blood Pressure Targets for Vasopressor Therapy Septic and Vasodilatory Shock

Targeting higher blood pressure targets may increase mortality in patients who have been treated with vasopressors for more than 6h. Lower blood pressure targets were not associated with patient‑important adverse events... read more

Risk Stratification Using Oxygenation in the First 24 Hours of Pediatric ARDS

Risk Stratification Using Oxygenation in the First 24 Hours of Pediatric ARDS

Oxygenation measured 24 hours after acute respiratory distress syndrome onset more accurately stratifies risk, relative to oxygenation at onset, in both children and adults. However, waiting 24 hours is problematic, especially... read more

Letting the Patient Decide: A Case Report of Self-Administered Sedation During Mechanical Ventilation

Letting the Patient Decide: A Case Report of Self-Administered Sedation During Mechanical Ventilation

It is common for critical care nurses to administer sedative medications to patients receiving mechanical ventilation. Although patient-controlled analgesia is frequently used in practice to promote effective self-management... read more

Monitoring the Relationship Between Changes in Cerebral Oxygenation and Electroencephalography Patterns During Cardiopulmonary Resuscitation

Monitoring the Relationship Between Changes in Cerebral Oxygenation and Electroencephalography Patterns During Cardiopulmonary Resuscitation

Real-time monitoring of cerebral oxygenation and function during cardiac arrest resuscitation is feasible. Although voltage suppression is the commonest electroencephalography pattern, other distinct patterns exist that may... read more

Tele-ICU Leads to Overall Reduction in ICU Mortality

Tele-ICU Leads to Overall Reduction in ICU Mortality

A new systematic review and meta-analysis has found that implementation of tele-ICU services was associated with an overall reduction in ICU mortality. Furthermore, in subgroup analysis, the pooled odds ratio for ICU mortality... read more

Expanding the Differential for Hypotension in the Pediatric Patient

Expanding the Differential for Hypotension in the Pediatric Patient

As many ED practitioners are aware, food allergies are common in the first 2 years of life, with a prevalence cited between 1-10% of the population. Most food allergies are IgE-mediated hypersensitivity reactions. Food protein-induced... read more

Determination of Brain Death Under Extracorporeal Life Support

Determination of Brain Death Under Extracorporeal Life Support

The worldwide use of extracorporeal lung/life support is increasing in severe lung failure (veno-venous extracorporeal membrane oxygenation, vvECMO) or in cardiac arrest/severe circulatory failure (veno-arterial ECMO, vaECMO).... read more

This Minimally Invasive Technique Could Reduce the Need for Open-Heart Surgery

This Minimally Invasive Technique Could Reduce the Need for Open-Heart Surgery

Currently, the majority of individuals who undergo transcather aortic valve replacement (TAVR), a minimally invasive alternative to open-heart surgery—are elderly or subject to compounding complications such as kidney disease.... read more

Airway Management in Microgravity

Airway Management in Microgravity

In the near future, space programs will shift their focus toward long‐duration interplanetary missions, in particular to the Moon and Mars. These exploration missions will be associated with an increased risk of acute medical... read more

A Surprising Way to Decrease Stress in Nursing

A Surprising Way to Decrease Stress in Nursing

What if I told you that it wasn't the patient load that was actually stressing nurses out in the workplace? Would you believe me? Most nurses go into the profession of nursing to care for sick patients. So even those days... read more

Increased Hospital-Based Physical Rehabilitation and Information Provision After ICU Discharge

Increased Hospital-Based Physical Rehabilitation and Information Provision After ICU Discharge

Post-ICU hospital-based rehabilitation, including increased physical and nutritional therapy plus information provision, did not improve physical recovery or HRQOL, but improved patient satisfaction with many aspects of recovery.... read more

Extravascular Lung Water as a Target for Intensive Care

Extravascular Lung Water as a Target for Intensive Care

Extravascular lung water (EVLW) remains a useful guide for monitoring pulmonary edema (PO) and vascular permeability in sepsis, acute respiratory distress syndrome (ARDS), and heart failure. In addition, EVLW has a prognostic... read more