Diagnostic Accuracy of Delirium Assessment Methods in Critical Care Patients
Delirium is a disorder of decreased ability to focus, sustain or shift attention, change in cognition and or perception. The main objective was to evaluate the diagnostic accuracy of Confusion Assessment Method for the ICU... read more
Concise Review of Critical Care, Trauma and Emergency Medicine
A Quick Reference Guide of ICU and Er Topics. Most commonly encountered clinical scenarios and relevant topics are summarized in an easy to understand format. Can be used as quick reference guide during rounds, or during... read more
Prone Positioning of ARDS Patients
A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study. While prone positioning (PP) has been shown to improve patient survival in... read more
On Diagnosing Sepsis
Two years ago, a panel appointed by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine, referred to as a consensus conference, proposed a new definition for sepsis and new diagnostic... read more
Animal-assisted Intervention in the ICU: A Tool for Humanization
The combination of an aging population and advances in critical care medicine is resulting in a growing number of survivors of critical illness. Survivors' descriptions of their stay in an intensive care unit (ICU) are frequently... read more
Trends of Incidence and Risk Factors of VAP in Elderly Patients Admitted to French ICUs
This study assesses trends and risk factors of ventilator-associated pneumonia (VAP) according to age, particularly in the elderly admitted to French ICUs between 2007 and 2014. Ventilator-associated pneumonia incidence is... read more
Clinical Care Review Systems in Healthcare
Clinical care review is the process of retrospectively examining potential errors or gaps in medical care, aiming for future practice improvement. The objective of our systematic review is to identify the current state of... read more
Tracheal Intubation in Critically Ill Patients
We performed a systematic review of randomized controlled studies evaluating any drug, technique or device aimed at improving the success rate or safety of tracheal intubation in the critically ill. We identified 22 trials... read more
Distributions and Behavior of Vital Signs in Critically Ill Children by Admission Diagnosis
This is the first study reporting distributions of continuously measured physiologic variables and trends in their behavior according to admission diagnosis in critically ill children. Differences detected between and within... read more
Noninvasive Ventilation in Hypercapnic COPD
Recently, Murphy and colleagues reported findings from a clinical trial designed to evaluate the effect of home noninvasive ventilation (NIV) with oxygen on time to readmission or death in patients with persistent hypercapnia... read more
R.E.B.E.L. EM – Fluid Responsiveness and the Six Guiding Principles of Fluid Resuscitation
Fluid resuscitation is a crucial aspect of emergency and critical care. Since the advent of the concept of early goal-directed therapy, we have placed a huge emphasis on aggressive fluid resuscitation in patients with severe... read more
REPROVE: Ceftazidime-avibactam Noninferior to Meropenem for Nosocomial Pneumonia
Ceftazidime-avibactam was noninferior to meropenem for nosocomial pneumonia including ventilator-associated pneumonia (VAP) from gram-negative organisms, results from the REPROVE trial demonstrated. Nosocomial or hospital-acquired... read more
Is Overall Mortality the Right Composite Endpoint in Clinical Trials of ARDS?
Most deaths in acute respiratory distress syndrome (ARDS) patients are not directly related to lung damage but to extrapulmonary multisystem organ failure. It would be challenging to prove that specific lung-directed therapies... read more
Persistence of Delirium after Cessation of Sedatives and Analgesics and Impact on Clinical Outcomes in Critically Ill Patients
As delirium is a common manifestation in critically ill patients and is associated with worse clinical outcomes, we sought to characterize the reversibility of delirium after discontinuation of sedation and to determine whether... read more
Conceptualizing Post Intensive Care Syndrome in Children
Post Intensive Care Syndrome in pediatrics (PICS-p) will help illuminate the phenomena of surviving childhood critical illness and guide outcomes measurement in the field. Empirical studies are now required to validate and... read more
The Sound of Air: Point-of-Care Lung Ultrasound in Perioperative Medicine
Lung ultrasound (LUS) has emerged as an effective and accurate goal-directed diagnostic tool that can be applied in real time for the bedside assessment of patients with respiratory symptoms and signs. Lung ultrasound has... read more
Music as Therapy in the ICU
Music has been shown to reduce respiratory, cardiac and blood pressure frequencies in response to the reduction of stress hormones. In a randomized clinical trial, it was shown to reduce anxiety and sedation doses/intervals... read more
Early Mobility in Critically Ill Patients
Kyle Enfield, MD, speaks with Wes Ely, MD, MPH, about his talk presented at the Multiprofessional Critical Care Review: Adult course in Rosemont, Illinois entitled, "Early Mobility in Critically Ill Patients: More to Come."... read more
Cognitive Development One Year After Infantile Critical Pertussis
Infants who survive critical pertussis often have neurodevelopmental deficits. These infants may benefit from routine neurodevelopmental screening. Of 196 eligible patients, 111 (57%) completed the Mullen Scales of Early... read more
Early Hemorrhage Control and Management of Trauma-induced Coagulopathy
Trauma resuscitation should focus on early goal-directed therapy with use of viscoelastic hemostatic assays while initially applying a ratio 1:1:1 driven transfusion therapy (with red blood cells, plasma and platelets) in... read more
Long-Term Cognitive Impairment after Hospitalization for Community-Acquired Pneumonia
Recent studies suggest older patients hospitalized for community-acquired pneumonia are at risk for new-onset cognitive impairment. The characteristics of long-term cognitive impairment after pneumonia, however, have not... read more
Recovery After Critical Illness: Putting the Puzzle Together
In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new... read more
