Ventilation Rate During Adult CPR with Tracheal Tube

The optimal ventilation rate during cardiopulmonary resuscitation (CPR) with a tracheal tube is unknown. A new systematic review finds that a ventilation rate recommendation of 10 min-1 during adult CPR with a secure airway... read more

Mechanisms of Severe Mortality-associated Bacterial Co-infections Following Influenza Virus Infection

The mechanisms of severe morbidity following influenza-bacteria co-infections mainly include failure of an antibacterial immune response and pathogen synergy. Moreover, failure to resume function and tolerance might be one... read more

Clinical Impact of COPD on Non-cystic Fibrosis Bronchiectasis

Clinical impact of chronic obstructive pulmonary disease on non-cystic fibrosis bronchiectasis. A study on 1,790 patients from the Spanish Bronchiectasis Historical Registry. Patients with BE related to COPD have the same... read more

Doctors frustrated that electronic records steal time from patients

Researchers asked doctors licensed to practice in Rhode Island the question: How does using an EHR affect your interaction with patients? They got an earful. Most who responded complained that electronic records undermined... read more

Patients with postoperative delirium more likely to suffer dementia

Delirium is common in elderly hospitalized patients, affecting an estimated 14 - 56% of patients. It frequently manifests as a sudden change in behavior, with patients suffering acute confusion, inattention, disorganized... read more

Effect of Obstructive Sleep Apnea Treatment on Renal Function in Patients with Cardiovascular Disease

Obstructive sleep apnea (OSA) is associated with impaired renal function, but uncertainty exists over whether OSA treatment can influence renal outcomes. Objectives: To determine the effects of continuous positive airway... read more

An Orthopedic Surgeon Explains: Diastolic Heart Failure

It seems that every now and then we have to deal with something other than the bones. As you can imagine, this is sub-optimal at best. Because bones. Anyhow, I’ve been asked to discuss one of those issues with you, and... read more

Link Between Diabetes and Hospital Readmission Rates

Patients with diabetes have higher rates of hospital readmission compared with patients without diabetes, according to a pilot study published in Clinical Diabetes and Endocrinology. In the first study, the readmission rate... read more

Growing Concerns of Hepatitis E in Europe

Cases of Hepatitis E in Europe have increased by 10x over 10 years, with 5617 cases in 2015. Testing, case definitions, diagnosis, and surveillance for HEV infection vary extensively across Europe, with only 20 member states... read more

Efficient Organization of ICUs with a Focus on Quality: The Non-Physician Provider

Adequate staffing in ICUs is an increasing problem worldwide. We would like to elaborate on staffing problems that arise in ICUs across Europe, including the Dutch situation. This staffing problem is caused by the increased... read more

When Evidence Says No, but Doctors Say Yes

Long after research contradicts common medical practices, patients continue to demand them and physicians continue to deliver. The result is an epidemic of unnecessary and unhelpful treatments.... read more

Airport CPR Training Kiosks

Three airports around the U.S. have joined an American Heart Association (AHA) initiative to provide hands-only CPR training kiosks for passengers waiting for flights. The Cleveland Hopkins International, Cincinnati/Northern... read more

Direct Oral Anticoagulant- or Warfarin-Related Major Bleeding

Direct oral anticoagulants (DOACs) have expanded the armamentarium for antithrombotic therapy. Although DOAC-related major bleeding was associated with favorable outcomes compared with warfarin in clinical trials, warfarin... read more

Role of Preventability in Redefining Failure to Rescue Among Major Trauma Patients

Failure to rescue (FTR) is defined as death after a major complication and has been adopted as a measure of quality in surgical patients. Current definitions of FTR are limited because they do not account for the influence... read more

The Intensive Care Medicine Research Agenda on Critically Ill Oncology and Hematology Patients

Over the coming years, accelerating progress against cancer will be associated with an increased number of patients who require life‑sustaining therapies for infectious or toxic chemotherapy‑related events. Major changes... read more

Reducing Brain Injury After Cardiac Arrest

Therapeutic hypothermia (TH) (32-34°C for 24 hours) should be mandatory practice for patients who are comatose after being resuscitated from out-of-hospital cardiac arrest, if the initial cardiac rhythm is either pulseless... read more

Virtual Hospital Monitors Patients at Eight Facilities

In a bunker-like former bank office near Tacoma' Hilltop neighborhood, 200 nurses, physicians and other health care staff spend their days treating scores of hospital patients they never meet using webcams, two-way speakers... read more

Psychological Burnout and the Intensive Care Practitioner

This review hopes to be practical and candid. Ultimately, whether burnout is present or not, these efforts can support a greater goal: to increase resilience, to aid retention, and to improve career guidance. Doctors are... read more

How to Beat Burnout

Burnout takes a toll on physicians, their patients, and their practices. Short visits, complicated patients, lack of control, electronic health record stress, and poor work-home balance can lead to physicians leaving practices... read more

Contact Precautions for Endemic MRSA and VRE

Physical barriers have been used to prevent infectious diseases dating back to leather gloves and coats used during the Black Death in medieval Europe. In the United States, isolation of persons with infections coincided... read more

Targeted Temperature Management and Neurologic Outcome After Out-of-Hospital Cardiac Arrest

In this randomized clinical trial enrolling 355 adults with out-of-hospital cardiac arrest, there was no significant difference in favorable neurologic outcome at 6 months for those treated for 48 hours (69%) vs 24 hours... read more

Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock

Several studies have reported a survival benefit for polymyxin B hemoperfusion treatment in patients with severe sepsis and septic shock. However, recently, a propensity-matched analysis and a randomized controlled trial... read more