Acute caffeine ingestion does not increase arrhythmias in patients with chronic systolic heart failure
Acute ingestion of caffeine did not increase the risk of ventricular or supraventricular arrhythmias as compared to placebo in patients with chronic systolic heart failure, either at rest or during a symptom-limited exercise... read more
New-Onset Atrial Fibrillation Post-CABG More Common, Lasts Longer in Men Than in Women
In the ongoing push to understand the link between CABG surgery and new-onset atrial fibrillation, a large, multicenter registry has found that women were at lower risk of developing post-CABG A-fib.... read more
Cellular Mechanisms of Prevention of Ischemia-Reperfusion Injury
Ischemic preconditioning is the phenomenon whereby brief periods of sublethal ischemia protect against a subsequent, more prolonged, ischemic insult.... read more
1-Hour AMI Rule; Early Steroids in Kawasaki Disease; The Gut in PAD
Sensitivity of the European Society of Cardiology's 1-hour algorithm for assessing acute MI with high-sensitivity cardiac troponin may be insufficient for some ED physicians to confidently send patients home.... read more
Cartilage From Nose Used to Repair Bum Knees
Using cells from the cartilage in patients' noses, Swiss doctors have successfully made patches to treat 10 adults whose knee cartilage was damaged by injury.... read more
Immune system of African Americans responds more strongly to bacterial infection, and it is partly genetic
A Canada-US study has demonstrated that Americans of African descent have a stronger immune response to infection compared to Americans of European descent.... read more
Landmark genetics study to improve prediction of heart disease recruits 20,000th participant
A team of researchers from the University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Unit (LCBRU) in conjunction with colleagues from Primary Care and Leicester and Leicestershire CCGs have recruited... read more
Spread of cancer linked to cell metabolism, study shows
Cellular metabolism in white blood cells can be manipulated to prevent the spread of cancer, VIB and KU Leuven researchers suggest in a new study.... read more
Impaired recycling of mitochondria in autism?
The new study shows that autophagy is defective in TSC. The scientists further showed that two existing classes of drugs counter the defect: the epilepsy drug carbamazepine, and drugs known as mTOR inhibitors.... read more
AHA Provides Guidance on Drug-Drug Interactions With Statins and CVD Medications
AHA has released a new scientific statement for managing clinically significant drug-drug interactions in patients who are prescribed statins and other agents used in the treatment of cardiovascular disease.... read more
Successful treatment with fecal microbiota transplantation in patients with multiple organ dysfunction syndrome and diarrhea following severe sepsis
The outcome of treating two patients with FMT indicates that restoration of the intestinal microbiota barrier can alleviate the infection and modulate the immune response.... read more
Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome
In sepsis-associated ARDS, hydrocortisone treatment was associated with a significant improvement in pulmonary physiology, but without a significant survival benefit.... read more
Blood products and procoagulants in traumatic bleeding
A host of preclinical and clinical studies have evaluated blood product availability and efficacy in trauma. Recently published randomized controlled trials have investigated the ratio of platelet:plasma:red cell transfusion... read more
Palliative-care boosts heart failure patient outcomes
Adding palliative care interventions to management of patients with advanced heart failure improved quality-of-life measures in two relatively small, controlled studies.... read more
Neuropilin 2 deficiency linked to inflammation-induced edema
A deficiency in neuropilin 2 receptors may result in prolonged fluid buildup after inflammation, researchers found in a study on edema and lymphedema.... read more
