Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome
In sepsis-associated ARDS, hydrocortisone treatment was associated with a significant improvement in pulmonary physiology, but without a significant survival benefit.... read more
Blood products and procoagulants in traumatic bleeding
A host of preclinical and clinical studies have evaluated blood product availability and efficacy in trauma. Recently published randomized controlled trials have investigated the ratio of platelet:plasma:red cell transfusion... read more
Palliative-care boosts heart failure patient outcomes
Adding palliative care interventions to management of patients with advanced heart failure improved quality-of-life measures in two relatively small, controlled studies.... read more
Neuropilin 2 deficiency linked to inflammation-induced edema
A deficiency in neuropilin 2 receptors may result in prolonged fluid buildup after inflammation, researchers found in a study on edema and lymphedema.... read more
Targeted thyroid hormone delivery reduces off-target effects
This work provides strong evidence that targeted delivery of T3 via hybridization to glucagon can be a potent treatment option for metabolic syndrome and associated diseases.... read more
Fatty Acid Levels May Help Predict Psychosis
A new psychosis prediction model that takes into account fatty acid levels is 70 percent accurate in predicting psychosis in "ultra-high risk" patients (those who are at greatest risk of having their first psychotic... read more
Can a CT Scan Determine Lung Age?
A recent study in the American Journal of Respiratory and Critical Care Medicine sought to characterize age-related lung changes using CT.... read more
IVC Filters Provide No Advantage in Trauma Care
Trauma patients who received an inferior vena cava (IVC) filter to prevent pulmonary embolism (PE) had no survival advantage, according to a new study.... read more
High-Flow Oxygen Not Inferior for Averting Reintubation
For high-risk critically ill patients who have undergone extubation, high-flow conditioned oxygen therapy is not inferior to noninvasive mechanical ventilation.... read more
More NOAC Comparisons See More Bleeding With Rivaroxaban: Is the ‘Writing on the Wall’?
Evidence is mounting, albeit from observational studies, that while all of the non-vitamin K antagonist oral anticoagulants (NOACs) appear to have similar efficacy in terms of stroke reduction in atrial fibrillation, they... read more
Levosimendan Doesn’t Prevent Acute Organ Dysfunction
For adults with sepsis, levosimendan does not prevent acute organ dysfunction.... read more
Conservative oxygen treatment linked to lower ICU mortality
A conservative protocol for oxygen therapy results in lower intensive care unit (ICU) mortality compared to conventional care.... read more
Molecular machines generate Nobel award for European researchers
Three EU-funded researchers have been awarded a share of the 2016 Nobel Prize in Chemistry for developing molecular machines including a tiny lift, artificial muscles and miniscule motors, that are a thousand times thinner... read more
