Dysbiosis Across Multiple Body Sites in Critically Ill Adult Surgical Patients
Current evidence suggests that symbiosis of commensal microflora play a significant role in health and illness. The effect that commensal microflora play in critical care is less well known.... read more
Smoking, vitamin D deficiency linked to early MS disability
Severe vitamin D deficiency and current smoking predicted accumulated disability in patients with clinically isolated syndrome, which can be a precursor to the development of multiple sclerosis.... read more
Gene therapy for LPLD patients linked to lower frequency and severity of pancreatitis
Up to 6 years after receiving a single treatment with the gene therapy product lipoprotein lipase (LPL), patients with the debilitating genetic disease LPL deficiency (LPLD) had about 50% fewer episodes of pancreatitis than... read more
ICDs appear not to improve overall survival in non-ischemic systolic HF
This paper reports the findings of the DANISH study, a multicenter, unblinded, randomized, controlled trial to compare outcomes in patients with non-ischemic systolic heart failure who received cardiac resynchronization therapy... read more
HDAC inhibitors show promise against cancer stem cells
A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate... read more
Newer blood thinning drugs safer for reducing atrial fibrillation
Although warfarin has been used for nearly 60 years, researchers say newer blood thinners are a better option for lowering stroke risk among atrial fibrillation patients because they work for a shorter time with fewer side... read more
VTE history in female relatives increases absolute thrombotic risk
A family history of thrombosis in women may increase the risk for venous thromboembolism in women taking oral contraceptives, according to the results of a cohort study.... read more
Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke
Compared to patients treated with medical therapy alone, patients with an ischemic stroke undergoing endovascular thrombectomy combined with medical therapy had lower rates of disability 3 months after their stroke.... read more
Beta-Lactam Infusion in Severe Sepsis (BLISS)
Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis.... read more
What goes into the first aid kit of the future?
A revolution is taking place in the recesses of bathroom mirrors and pantry cabinets as a new wave of gadgets expand our conception of the First Aid Kit.... read more
FDA approves automated insulin delivery device for type 1 diabetes
The Food and Drug Administration (FDA) has approved a device that automatically monitors blood glucose levels and delivers insulin when appropriate, for people aged 14 years and older who have type 1 diabetes.... read more
Omega-3 could help prevent environmentally induced lupus
A new study suggests that docosahexaenoic acid - a type of omega-3 present in fish oil and dietary supplements - has the potential to prevent lupus, after finding the fatty acid blocked a known trigger of the disease.... read more
Fear of stigma or sanction keeps many doctors from revealing mental health issues
Even as doctors across America encourage their patients to share concerns about depression, anxiety and other concerns, so they can get help from modern treatments, a new study suggests the doctors may be less likely to seek... read more
HPV Vaccine More Effective Than Thought
The vaccine against human papillomavirus (HPV) infection, which doctors believe causes most cases of cervical cancer, appears even more effective than believed, a new study finds.... read more
Scientists reveal how signals from pathogenic bacteria reach danger sensors of cells
Researchers at St. Jude Children's Research Hospital have discovered the way signals from infectious bacteria gain entry into the cytoplasm of host cells to activate disease-fighting inflammasomes. Inflammasomes are... read more
A Simple Breath Test Can Spot Pneumonia And Lower Antibiotic Overuse
A simple test could be all physicians need to determine if they need to prescribe antibiotics.... read more
Bifunctional drug could treat tumors resistant to current mTOR inhibitors
The first known bifunctional inhibitor for the mechanistic target of rapamycin (mTOR) protein was developed to overcome current known mechanisms of tumor resistance to mTOR inhibitors.... read more
