Secretomic Approach Value in COVID-19 Viral Pneumonia Among Patients With Respiratory Distress

this article presents an innovative and promising secretomic analysis to distinguish VPP patients from NV-ICU patients using combinations of protein markers. Among the identified proteins, ficolin-3 and proteoglycan-4 appear... read more

Prevalence and Survival of Prolonged VV ECMO for ARDS

The understanding of prolonged venovenous extracorporeal membrane oxygenation (VV ECMO) in the setting of acute respiratory distress syndrome (ARDS) is evolving and durations of support once considered extreme are now commonplace.... read more

PEEP May Cause Harm in Less Severe ARDS

A higher positive end-expiratory pressure (PEEP) strategy may cause harm in adult patients with acute respiratory distress syndrome (ARDS) whose subphenotype is characterized by less inflammation and lower severity of illness. The... read more

Critical Care Companion: Your Guide To ICU Nursing

Critical Care Companion: Your Guide To ICU Nursing

Step into the dynamic and demanding world of Intensive Care Unit (ICU) nursing with Critical Care Companion: Your Guide to ICU Nursing by Alysha Edwards. This indispensable guide is crafted to support both novice and experienced... read more

The Existence of Adrenal Insufficiency in COVID-19 Patients with Pneumonia

Patients with a history of COVID-19 pneumonia who present with clinical symptoms such as shock, nausea, vomiting, and fatigue should have hypocortisolism included in the differential diagnosis. These patients should also... read more

COVID-19 Infections Are Growing

Large areas of the US are experiencing a significant spread of COVID-19, with the pandemic reaching alarming levels. Data from the Centers for Disease Control and Prevention indicates that the spread of the disease has officially... read more

Ketones Alleviates COVID-19-related ARDS

In this randomized controlled trial, supplementation with beta-hydroxybutyrate improved inflammatory biomarkers and reduced the length of hospitalization in adults with COVID-19–related acute respiratory distress syndrome... read more

Dexamethasone Systemic Effects in Severe COVID-19

Dexamethasone is the standard of care for critically ill patients with COVID-19, but the mechanisms by which it decreases mortality and its immunological effects in this setting are not understood. Here we perform bulk... read more

The Airway Manual: Practical Approach to Airway Management

The Airway Manual: Practical Approach to Airway Management

The book provides up-to-date and easy to understand information on airway management with special emphasis on practical management along with required theory background and key points. It covers all aspects of airway management... read more

Emergency Department Disposition and Mortality in COVID‐19 Patients with ARDS

Compared to direct ICU admission, admission from the ED to the ward is associated with increased mortality in patients who meet COVID‐19 ARDS criteria during their hospitalization, despite lower 4C and similar SAPS‐III... read more

Endothelial Dysfunction and Persistent Inflammation in Severe Post-COVID-19 Patients

Six months after ICU discharge from severe ARDS secondary to COVID-19, patients with gas exchange impairment exhibit evidence of systemic inflammation, along with elevated ICAM-1 levels, ultimately resulting in increased... read more

BARDA Selected Host-directed Therapeutic Candidates to Address ARDS

Biomedical Advanced Research and Development Authority (BARDA) has selected host-directed therapeutic candidates for inclusion in a phase 2 platform clinical trial to address acute respiratory distress syndrome (ARDS). Currently,... read more

Cardiac Arrest During a Ferric Derisomaltose Infusion Followed by Complete Heart Block

Bradycardia and heart block are rarely reported in the parenteral iron literature. Although rare, it may be reasonable to consider parenteral iron as a toxicological etiology for patients presenting with complete heart block... read more

Impact of extended lung protection during mechanical ventilation on lung recovery in patients with COVID-19 ARDS

The extended lung protection with strict control of ΔP for moderate to severe ARDS plus deranged mechanics is feasible and could be implemented in this pilot study with some beneficial impact on the recovery of lung function.... read more

Handbook of Intravenous Fluids

Handbook of Intravenous Fluids

This easy to use pocket book covers all aspects of intravenous fluid therapy in critically ill patients from applied physiology to bedside clinical management succinctly. It includes updated and evidence-based content on... read more

Weaning From Mechanical Ventilation in ICUs Across 50 Countries

Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients... read more

Cardiac Arrest Following Prone Positioning

The complications that can arise from the prone position are often underestimated. Proceduralists, surgeons, and anesthesiologists need to be thoroughly knowledgeable about the common physiological changes that can occur... read more