Knowledge of Constituent Ingredients in Enteral Nutrition Formulas Can Make a Difference in Patient Response to Enteral Feeding

Knowledge of Constituent Ingredients in Enteral Nutrition Formulas Can Make a Difference in Patient Response to Enteral Feeding

The selection of an EF should be a conscientious process based on a number of factors, including the patient's clinical and medical status. The ingredients need to be carefully evaluated in their quality and quantity as they... read more

The Future of Mechanical Ventilation

The Future of Mechanical Ventilation

The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS) arise from two main causes: unphysiological increases of transpulmonary pressure and unphysiological increases/decreases of pleural... read more

Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency – Part II

Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency – Part II

This part II of the guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients is related to acute illnesses that may be complicated by CIRCI. We... read more

Urinary Oxygenation as a Surrogate Measure of Medullary Oxygenation During Angiotensin II Therapy in Septic AKI

Urinary Oxygenation as a Surrogate Measure of Medullary Oxygenation During Angiotensin II Therapy in Septic AKI

In septic acute kidney injury (AKI), renal medullary and urinary hypoxia developed several hours before increases in currently used biomarkers. Angiotensin II transiently improved renal function without worsening medullary... read more

FDA Approves Angiotensin-II for Septic Shock

FDA Approves Angiotensin-II for Septic Shock

The FDA approved angiotensin-II (Giapreza) as a new intravenous vasopressor for septic shock and other forms of distributive shock. The first new FDA-approved vasopressor in decades, angiotensin-II could significantly change... read more

Optimizing Quality and Efficiency of Critical Care Delivery

Optimizing Quality and Efficiency of Critical Care Delivery

Providing "health" care is expensive, and providing "sick" care is even more expensive. Here we will outline a newly packaged, high-yield opportunity for your institution regarding optimization of your critical care service... read more

Meta-Analysis Shows Mixed Results with Palliative Care

Meta-Analysis Shows Mixed Results with Palliative Care

Palliative care was tied to some improvements in quality of life (QOL) in critically ill patients, but the impact on caregiver outcomes was mixed, and there was no significant association between palliative care delivery... read more

Integration of Nurse Practitioners Into the Critical Care Team

Integration of Nurse Practitioners Into the Critical Care Team

As the demands of critical care medicine increase one viable option to meet needs is the addition of a nurse practitioner to the traditional structure of the critical care team. The purpose of this article is to convey our... read more

Predicting the Hemodynamic Response to Prone Positioning

Predicting the Hemodynamic Response to Prone Positioning

Graphical models of physiology are heuristically appealing as they facilitate qualitative conclusions at the bedside of the critically ill. Historically, the Rahn diagram has portrayed the physiology of the lungs, chest wall... read more

The Hidden Faces of Sepsis, What Do They Tell Us?

The Hidden Faces of Sepsis, What Do They Tell Us?

Based on the patients' perspective Nutma sheds light on the hidden faces of sepsis, calling for more expertise on sepsis sequelae. She also offers recommendations to improve recovery and outcome. Sepsis really caught me by... read more

PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock

PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock

In patients who have acute myocardial infarction with cardiogenic shock, early revascularization of the culprit artery by means of percutaneous coronary intervention (PCI) improves outcomes. However, the majority of patients... read more

Guidelines for the Content of Statistical Analysis Plans in Clinical Trials

Guidelines for the Content of Statistical Analysis Plans in Clinical Trials

While guidance on statistical principles for clinical trials exists, there is an absence of guidance covering the required content of statistical analysis plans (SAPs) to support transparency and reproducibility. Recommendations... read more

Prognostic Effect and Longitudinal Hemodynamic Assessment of Borderline Pulmonary Hypertension

Prognostic Effect and Longitudinal Hemodynamic Assessment of Borderline Pulmonary Hypertension

Borderline PH is common in patients undergoing RHC and is associated with significant comorbidities, progression to overt PH, and decreased survival. Small increases in mPAP, even at values currently considered normal, are... read more

Understanding How to Improve Quality and Value for Patients With AMI

Understanding How to Improve Quality and Value for Patients With AMI

Although the United States lags behind comparable nations in many health measures, mortality following acute myocardial infarction (AMI) is lower in the United States than in many other developed countries, including Finland,... read more

Investing in Physicians’ Well-being is Just Good Business

Investing in Physicians’ Well-being is Just Good Business

The moral and ethical reason for physician practices, hospitals and academic centers to address physician burnout should be obvious, but a new medical journal article makes the case for why addressing doctors' well-being... read more

Alleviating ICU Survivors’ Burden

Alleviating ICU Survivors’ Burden

In a review paper, a team of international researchers highlights how critical illness and critical care affect longer-term outcomes. According to the authors, the severity of acute illness determines the degree of impairment... read more

What Can Psychologists Do in Intensive Care?

As awareness has grown of the great distress intensive care patients may suffer, units have begun recruiting psychologists to their teams. Intensive care unit psychologists aim to assess and reduce distress for patients,... read more