Acute Kidney Injury is not Associated with IV Contrast Use in the ED

Acute Kidney Injury is not Associated with IV Contrast Use in the ED

Intravenous (IV) iodinated contrast media is used routinely to improve the accuracy of computed tomography (CT) in the emergency department (ED).  Prior studies have linked contrast media with the development of acute kidney... read more

THRIVE Developments

THRIVE Developments

The THRIVE initiative is proud to announce the selection of 10 institutions to a new Post Intensive Care Unit (ICU) Clinic Collaborative. The purpose of the THRIVE Post ICU Clinic Collaborative is to build an international... read more

Relative Bradycardia in Patients With Septic Shock Requiring

Relative Bradycardia in Patients With Septic Shock Requiring

Relative bradycardia in patients with septic shock is associated with lower mortality, even after adjustment for confounding. Our data support expanded investigation into whether inducing relative bradycardia will benefit... read more

Pre-hospital therapeutic hypothermia: The RINSE trial

Pre-hospital therapeutic hypothermia: The RINSE trial

Therapeutic hypothermia has had a bit of a rollercoaster ride over the last few years. It was all the rage following three small trials, which initially suggested a significant benefit from cooling patients to 33C following... read more

EM-Critical Care: Aortic Dissection

EM-Critical Care: Aortic Dissection

Thoracic Aortic Dissection A difficult to diagnose, uncommon, and potentially fatal condition: Emergency Medicine at its finest!   Let’s talk about a patient we think see every day in the ED. A man comes in complaining... read more

Meta-analysis confirms EGDT for sepsis is unhelpful and wasteful (PRISM)

Meta-analysis confirms EGDT for sepsis is unhelpful and wasteful (PRISM)

Three large, well-conducted randomized trials around the world (ProCESS, ARISE, and ProMISe) all agreed: use of early goal-directed therapy (EGDT) for sepsis does not improve mortality or any other important clinical outcome.... read more

2017’s Tell-All Social Media Guide for Doctors and Hospitals

2017’s Tell-All Social Media Guide for Doctors and Hospitals

You may have thought "this too shall pass", but now you’ve realized the inevitable truth: social media is here to stay. If you’ve never given social media much thought when it comes to your physician practice... read more

ICU Study Shows Significant Reduction in Time to Blood Gas Result using Sphere Medical’s Proxima

ICU Study Shows Significant Reduction in Time to Blood Gas Result using Sphere Medical’s Proxima

A recent time and motion study by University Hospital Southampton demonstrated a 1.5 minute (>20%) reduction in time to blood gas results when using the Proxima bedside blood gas monitoring system. The study also found... read more

The Sick and the Dead: Evidence-Based Trauma Resuscitation

The Sick and the Dead: Evidence-Based Trauma Resuscitation

The science of trauma resuscitation has undergone a fairly massive evolution in the past decade. This talk was our attempt to summarize the best-of-the-best in trauma literature from the past several years, and package it... read more

Early, Goal-Directed Therapy for Septic Shock

Early, Goal-Directed Therapy for Septic Shock

After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ProMISe) showed no benefit. This... read more

How Redesigning The Abrasive Alarms Of Hospital Soundscapes Can Save Lives

How Redesigning The Abrasive Alarms Of Hospital Soundscapes Can Save Lives

After a recent hospital stay filled with frightening, uselessly beeping gadgets, an ambient musician set to work reinventing the aural landscape of medicine, to make life calmer for patients and easier for doctors. ... read more

The Case for CRISPR-Cas9

The Case for CRISPR-Cas9

Few techniques in the history of modern science have made as large an impact in as short a time as CRISPR-Cas9. Only a few years after the technique was first described, its inventors are predicted to be on the shortlist... read more

How to keep up with the scientific literature

How to keep up with the scientific literature

Few aspects of scientific work may be as crucial - and yet as easy to neglect - as reading the literature. Beginning a new research project or writing a grant application can be good opportunities for extensive literature... read more

Draft quality standard on rehabilitation after a critical illness

Draft quality standard on rehabilitation after a critical illness

New guideline to be published in 2017. We've published a draft quality standard on rehabilitation after a critical illness: Quality standard consultation. You can now comment on this draft quality standard. Closing date... read more

Genomics, Health Disparities, and Missed Opportunities for the Nation’s Research Agenda

Genomics, Health Disparities, and Missed Opportunities for the Nation’s Research Agenda

The completion of the Human Genome Project occurred at a time of increasing public attention to health disparities. In 2004, Sankar and colleagues1 suggested that this coincidental timing resulted in an inappropriate emphasis... read more

How Well Do Leapfrog Safe Practices Scores Correlate with Hospital Compare Ratings and Penalties

How Well Do Leapfrog Safe Practices Scores Correlate with Hospital Compare Ratings and Penalties

Hospital quality scores are publicly available, but the extent to which they reflect patient safety remains controversial. This study compared measures from the Leapfrog Group, which incorporates mandatory publicly reported... read more

A Letter to a Young Emergency Doctor

A Letter to a Young Emergency Doctor

When I was starting out, I was told there were three types of doctors doing emergency medicine: missionaries, adrenaline junkies, and fools. I was all three. Now that I’m burning out at the other end of my career, I have... read more