Stories Category: Intensive Care
Use of Hemoadsorption in Patients With Severe Intoxication Requiring ECMO
Drugs intoxications often lead to severe vasoplegia and cardiogenic shock, and VA-ECMO represents a viable therapy option. However, as cardiopulmonary support is not contributing to the removal of the causal agent from the... read more
SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus disease 2019 (COVID–19) pandemic, severely affecting public health and the global economy. Adaptive immunity plays a crucial role... read more
Year of the Nurse: A 2020 Covid-19 Pandemic Memoir
This book is for everyone, nurse or otherwise, who is furious about how 2020 went down and how 2021 is going. #1 Amazon Bestseller in Critical & Intensive Care Nursing #1 Amazon Bestseller in Mental Health Nursing #1... read more
Endothelial Glycocalyx Degradation Contributes to Metabolic Acidosis in Children After Cardiopulmonary Bypass Surgery
Our data show that metabolic acidosis (increased strong ion gap) is associated with plasma concentration of heparan sulfate, a negatively charged glycosaminoglycan cleaved from the endothelial glycocalyx during cardiopulmonary... read more
Critical Illness in Patients with Hematologic Malignancy
Critical illness in patients with a newly diagnosed hematologic malignancy is frequent, occurring early after diagnosis. Certain baseline characteristics can help identify those patients at the highest risk. A total of... read more
Adrenal Insufficiency in Patients Taking Benralizumab as Corticosteroid Sparing Therapy
A personalised regimen of tapering oral corticosteroids in the presence of the anti-IL5 receptor α-directed cytolytic monoclonal antibody benralizumab can help to achieve elimination or dose reduction of oral corticosteroids... read more
Effect of Adjunctive Vitamin C, Glucocorticoids, and Vitamin B1 on Sepsis
We aimed to compare the effects of vitamin C, glucocorticoids, vitamin B1, combinations of these drugs, and placebo or usual care on longer-term mortality in adults with sepsis or septic shock. MEDLINE, Embase, CENTRAL, ClinicalTrials.gov... read more
Acute Eosinophilic Pneumonia Secondary to Daptomycin
Daptomycin is an antimicrobial agent with activity against gram-positive bacteria that is usually reserved for severe infections. Acute eosinophilic pneumonia (AEP) is an increasingly rare side effect that can manifest after... read more
Seven Signs of Life: Stories from an Intensive Care Doctor
Seven Signs of Life encompasses intensive care stories centered around patients and as a means to explain the ICU to the non-clinician. However, Aoife Abbey organises her book by emotion, not by body system. This clever structure... read more
How protein-based COVID vaccines could change the pandemic
Unlike the relatively new technologies that the mRNA and viral-vector COVID-19 shots are based on, protein vaccines have been used for decades to protect people from hepatitis, shingles and other viral infections. To... read more
Not all COVID waves look the same. Here’s a snapshot of the Delta surge
Waves of Covid can give you an awful sense of déjà vu. As "Hot Vax Summer" gave way early to Delta-anxious fall, you could be forgiven for feeling a familiar sense of dread, not so different from what you’d felt before... read more
One Night in the ER
Follow Dr. Jim McCray through a single twelve-hour night shift working in the emergency room of a small Midwestern hospital. The fast-paced writing chronicles Dr. McCray's experience with wit and candor as he manages... read more
The Unsung Heroes: Respiratory Therapists
Working day after day, year after year, in a busy high acuity ICU, we all have become a "second family." The public doesn't hear much about respiratory therapists, especially during this COVID nightmare. But they have... read more
Point of Care Venous Doppler Ultrasound
Accurate assessment of the hemodynamic status is vital for appropriate management of patients with critical illness. As such, there has been a constant quest for reliable and non-invasive bedside tools to assess and monitor... read more
Pulmonary Hypertension: Controversial and Emerging Topics
This book is a clinical guide to controversial and emerging topics in pulmonary hypertension. There are multiple challenges and unanswered questions encountered by clinicians that evaluate, diagnose and treat patients with... read more
EDS: Early or Late in the Diagnostic Process?
Electronic differential diagnostic support (EDS) increased the number of diagnostic hypotheses and the likelihood of the correct diagnosis appearing in the differential, and these effects persisted irrespective of whether... read more
Mechanically Ventilated COVID-19 Patients: Long-term Survival Study
The long-term survival of mechanically ventilated patients with severe COVID-19 reaches more than 50% and may help to provide individualized risk stratification and potential treatments. 868 patients were included (median... read more
