Methylene Blue Reduced Length of Stay in ICU

Methylene Blue Reduced Length of Stay in ICU

In patients with septic shock, methylene blue (MB) initiated within 24 h reduced time to vasopressor discontinuation and increased vasopressor-free days at 28 days. It also reduced length of stay in ICU and hospital without... read more

Is It Time to Abandon Routine Mask Ventilation Before Intubation?

Is It Time to Abandon Routine Mask Ventilation Before Intubation?

Mask ventilation in the period between induction and intubation has traditionally been used to confirm the ability to ventilate the patient while awaiting the onset of adequate neuromuscular blockade. However, recent studies... read more

Intensive Care in Nephrology

Intensive Care in Nephrology

The field of intensive care in nephrology is a rapidly evolving one, with research starting to translate into clinical guidelines and standards. Encompassing core subjects in critical care and nephrology, as well as specific... read more

Delirium Prevention in the ICU: Melatonin or Ramelteon

Delirium Prevention in the ICU: Melatonin or Ramelteon

Melatonin modulates the circadian rhythm and has been studied as a preventive measure against the development of delirium in hospitalized patients. Such an effect may be more evident in patients admitted to the ICU, but findings... read more

Delphi Approach to 5-level Priority Triage Systems

Delphi Approach to 5-level Priority Triage Systems

This study proposes a standard of 49 outcomes divided into two sets tied to red and orange priority respectively, to be used when evaluating 5-level priority triage systems; Lund Outcome Set for Evaluation of Triage (LOSET).... read more

Predicting Readmission or Death After Discharge From the ICU with Machine Learning

Predicting Readmission or Death After Discharge From the ICU with Machine Learning

In this era of expanding availability of ML models, external validation and retraining are key steps to consider before applying machine learning (ML) models to new settings. Clinicians and decision-makers should take... read more

Increased Risk of Hospitalization in Celiac Disease with COVID-19 Infection Is Mitigated by Vaccination

Increased Risk of Hospitalization in Celiac Disease with COVID-19 Infection Is Mitigated by Vaccination

Celiac disease (CD) patients with COVID-19 have a higher risk of hospitalization compared with non-CD referents. This risk is mitigated by vaccination in CD patients as it is in non-CD referents. ICU requirement occurred... read more

Early evaluation of heart rate variability can predict the outcome of patients in the ICU

Early evaluation of heart rate variability can predict the outcome of patients in the ICU

The study evaluated the use of heart rate variability (HRV) to predict the outcome of patients in the ICU. HRV is a way to evaluate the cardiac effects of the autonomic nervous system, and a relation between HRV and outcome... read more

A Young Doctor’s Perspective Was Forever Changed by ICU Experience

A Young Doctor’s Perspective Was Forever Changed by ICU Experience

A healthy 30-year-old doctor had an unexpected medical emergency while preparing for a procedure, which led to the discovery of a small hemorrhage in her dorsal brainstem. She was transferred to the neuro ICU and experienced... read more

I Was a Doctor Through COVID. Then One Case Pushed Me Over the Edge

I Was a Doctor Through COVID. Then One Case Pushed Me Over the Edge

On some days I can almost forget that COVID ever happened. The old rhythms of the ICU at University College London, where I am a consultant in critical care and anesthesia, have returned. The bed pressures, the worrying cases,... read more

Life Lessons After a Career in Intensive Care Medicine

Life Lessons After a Career in Intensive Care Medicine

I have spent the past 30 years working in intensive care medicine. I was drawn to intensive care as a trainee for several reasons. First, I enjoyed the opportunity to care for the sickest patients in the hospital and to use... read more

Bayesian Reanalysis of the Standard vs. Accelerated Initiation of RRT in AKI Trial

Bayesian Reanalysis of the Standard vs. Accelerated Initiation of RRT in AKI Trial

Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy (RRT) in Acute Kidney Injury (STARRT-AKI)... read more

Use of Cardiac POCUS in Diagnosis of HFrEF in a Patient with Ischemic Stroke

Use of Cardiac POCUS in Diagnosis of HFrEF in a Patient with Ischemic Stroke

Ischemic strokes in younger adults, those 18 to 50 years old, account for approximately 10% to 15% of all ischemic strokes. Risk factors for stroke between younger and older patients tend to be similar. Younger patients... read more

Acid-Base Disorders in the Critically III Patient

Acid-Base Disorders in the Critically III Patient

Acid-base disorders are common in the intensive care unit. By utilizing a systematic approach to their diagnosis, it is easy to identify both simple and mixed disturbances. These disorders are divided into four major categories:... read more