Tag: AKI
Blood pressure deficits in acute kidney injury: not all about the mean arterial pressure?
Acute kidney injury (AKI) is associated with increased morbidity and mortality. Although there are many causes of AKI, it is known that patients undergoing high-risk surgery are known to be at significant risk. Although much... read more
Implications of Prevalent Noncardiac Disease in the Cardiac ICU
Half of >1000 patients of admitted to the cardiac intensive care unit (ICU) at a major tertiary-care center over about 1 year also had acute respiratory failure, acute kidney injury, or sepsis. Those with lung or kidney... read more
Venous congestion: are we adding insult to kidney injury in sepsis?
In critical illness, septic shock is a contributing factor in nearly half of all cases of acute kidney injury (AKI). Traditional approaches to prevention of organ dysfunction in early sepsis have focused on prevention of... read more
Acute Kidney Injury is not Associated with IV Contrast Use in the ED
Intravenous (IV) iodinated contrast media is used routinely to improve the accuracy of computed tomography (CT) in the emergency department (ED). Prior studies have linked contrast media with the development of acute kidney... read more
Recovery after Acute Kidney Injury
Little is known about how acute kidney injury (AKI) resolves, and whether patterns of reversal of renal dysfunction differ among patients with respect to ultimate recovery. We have identified five distinct recovery phenotypes... read more
Use of Lab Tests in Detecting Kidney Disease
This systematic review summarizes evidence supporting the use of laboratory tests for glomerular filtration rate and albuminuria to detect and stage kidney disease in adults. Detection and staging of acute and chronic kidney... read more
Contrast-Induced Nephropathy: Confounding Causation
Comparing the methodological rigor of more recent CIN studies to those in the past, it seems clear that earlier studies purporting a causal relationship between AKI and contrast administration were only identifying an association... read more
Hemolytic Uremic Syndrome (HUS): Pearls and Pitfalls
A three-year-old male presents with mom for seven days of fever, diarrhea, and decreased activity. When you walk into the room, you note a listless-appearing boy with pallor. His eyes appear sunken. He is tachycardic, tachypneic,... read more
Ureteral stents, sepsis and acute kidney injury: Iatrogenic imperfecta!
Case presentation A 62-year-old woman with a past history of placement of bilateral ureteral "JJ" stents, presented to the hospital complaining of fever, chills, abdominal pain, oliguria and was found to be hypotensive.... read more
Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI
Except for urinary pH, none of the outcomes differed between the two groups. Among ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associated... read more
Culture-Negative Severe Sepsis: Nationwide Trends and Outcomes
CNSS among hospitalized patients is common, and its proportion is on the rise. CNSS is associated with greater acute organ dysfunction and mortality. Having CNSS is an independent predictor of death. Of 6,843,279 admissions... read more
Three-year mortality in 30 day survivors of critical care with AKI
Acute kidney injury was not an independent risk factor for 3-year mortality among 30-day survivors. Increased 3-year mortality among patients with AKI who survive critical illness may not be related to AKI per se, but rather... read more
Vasopressin vs. norepinephrine for vasoplegic shock after cardiac surgery
Patients in the VANISH trial treated with vasopressin had a lower incidence of renal failure requiring hemodialysis. However, this was a secondary endpoint which seemed to contradict the primary endpoint (defined as a milder... read more
Cardiotoxicity from Ca Immune Tx; Worried Sick; Bee Sting Heart Damage
Worried sick? Anxiety about health was associated with increased likelihood of ischemic heart disease.... read more
Baxter initiates late-stage study of novel therapy for acute kidney injury
Baxter International commences a Phase 3 clinical trial assessing an investigational drug, Prismocitrate 18, that combines a citrate anticoagulant and renal replacement solution.... read more
Genetic Loci Linked to Acute Kidney Injury
Four single-nucleotide polymorphisms at two loci identified in discovery, replication populations.... read more
New Research Shows NEPHROCHECK Test Predicts Acute Kidney Injury Risk For Transaortic Valve Implant Patients
Astute Medical, Inc., developer of biomarkers for better healthcare, today said that newly published findings show that the Company's NEPHROCHECK Test may help physicians identify risk of a serious complication in patients... read more
