Tag: AKI
Recovery after Acute Kidney Injury
Little is known about how acute kidney injury (AKI) resolves, and whether patterns of reversal of renal dysfunction differ among patients with respect to ultimate recovery. We have identified five distinct recovery phenotypes... read more
Use of Lab Tests in Detecting Kidney Disease
This systematic review summarizes evidence supporting the use of laboratory tests for glomerular filtration rate and albuminuria to detect and stage kidney disease in adults. Detection and staging of acute and chronic kidney... read more
Contrast-Induced Nephropathy: Confounding Causation
Comparing the methodological rigor of more recent CIN studies to those in the past, it seems clear that earlier studies purporting a causal relationship between AKI and contrast administration were only identifying an association... read more
Hemolytic Uremic Syndrome (HUS): Pearls and Pitfalls
A three-year-old male presents with mom for seven days of fever, diarrhea, and decreased activity. When you walk into the room, you note a listless-appearing boy with pallor. His eyes appear sunken. He is tachycardic, tachypneic,... read more
Ureteral stents, sepsis and acute kidney injury: Iatrogenic imperfecta!
Case presentation A 62-year-old woman with a past history of placement of bilateral ureteral "JJ" stents, presented to the hospital complaining of fever, chills, abdominal pain, oliguria and was found to be hypotensive.... read more
Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI
Except for urinary pH, none of the outcomes differed between the two groups. Among ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associated... read more
Culture-Negative Severe Sepsis: Nationwide Trends and Outcomes
CNSS among hospitalized patients is common, and its proportion is on the rise. CNSS is associated with greater acute organ dysfunction and mortality. Having CNSS is an independent predictor of death. Of 6,843,279 admissions... read more
Three-year mortality in 30 day survivors of critical care with AKI
Acute kidney injury was not an independent risk factor for 3-year mortality among 30-day survivors. Increased 3-year mortality among patients with AKI who survive critical illness may not be related to AKI per se, but rather... read more
Vasopressin vs. norepinephrine for vasoplegic shock after cardiac surgery
Patients in the VANISH trial treated with vasopressin had a lower incidence of renal failure requiring hemodialysis. However, this was a secondary endpoint which seemed to contradict the primary endpoint (defined as a milder... read more
Cardiotoxicity from Ca Immune Tx; Worried Sick; Bee Sting Heart Damage
Worried sick? Anxiety about health was associated with increased likelihood of ischemic heart disease.... read more
Baxter initiates late-stage study of novel therapy for acute kidney injury
Baxter International commences a Phase 3 clinical trial assessing an investigational drug, Prismocitrate 18, that combines a citrate anticoagulant and renal replacement solution.... read more
Genetic Loci Linked to Acute Kidney Injury
Four single-nucleotide polymorphisms at two loci identified in discovery, replication populations.... read more
New Research Shows NEPHROCHECK Test Predicts Acute Kidney Injury Risk For Transaortic Valve Implant Patients
Astute Medical, Inc., developer of biomarkers for better healthcare, today said that newly published findings show that the Company's NEPHROCHECK Test may help physicians identify risk of a serious complication in patients... read more
Effect of atorvastatin on the incidence of acute kidney injury following valvular heart surgery
Statins, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors have the potential to reduce acute kidney injury (AKI) after cardiac surgery through their pleiotropic properties. Here we studied the preventive... read more
Earlier Renal Replacement Therapy for AKI? Not So Fast, Says Dr Berns
The AKIKI study was published in the New England Journal of Medicine; ELAIN was published in JAMA. If you have not read them, you should, if for no other reason than that your colleagues are likely to ask about them.... read more
Is Timing Really Everything With RRT?
For years we have been told that early interventions result in better patient outcomes. Early cardiac catheterization results in more preserved myocardial function.... read more
Utilising the immune system in the fight against sepsis – On Medicine
In this blog, Dr. Naoshi Takeyama, Senior Editor of Journal of Intensive Care, discusses about how knowledge of immuno-oncology can also be applied to strategies for managing sepsis and severe trauma.... read more
