Ureteral stents, sepsis and acute kidney injury: Iatrogenic imperfecta!

Ureteral stents, sepsis and acute kidney injury: Iatrogenic imperfecta!

Case presentation A 62-year-old woman with a past history of placement of bilateral ureteral "JJ" stents, presented to the hospital complaining of fever, chills, abdominal pain, oliguria and was found to be hypotensive.... read more

Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI

Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI

Except for urinary pH, none of the outcomes differed between the two groups. Among ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associated... read more

Culture-Negative Severe Sepsis: Nationwide Trends and Outcomes

Culture-Negative Severe Sepsis: Nationwide Trends and Outcomes

CNSS among hospitalized patients is common, and its proportion is on the rise. CNSS is associated with greater acute organ dysfunction and mortality. Having CNSS is an independent predictor of death. Of 6,843,279 admissions... read more

Three-year mortality in 30 day survivors of critical care with AKI

Three-year mortality in 30 day survivors of critical care with AKI

Acute kidney injury was not an independent risk factor for 3-year mortality among 30-day survivors. Increased 3-year mortality among patients with AKI who survive critical illness may not be related to AKI per se, but rather... read more

Vasopressin vs. norepinephrine for vasoplegic shock after cardiac surgery

Vasopressin vs. norepinephrine for vasoplegic shock after cardiac surgery

Patients in the VANISH trial treated with vasopressin had a lower incidence of renal failure requiring hemodialysis. However, this was a secondary endpoint which seemed to contradict the primary endpoint (defined as a milder... read more

Cardiotoxicity from Ca Immune Tx; Worried Sick; Bee Sting Heart Damage

Cardiotoxicity from Ca Immune Tx; Worried Sick; Bee Sting Heart Damage

Worried sick? Anxiety about health was associated with increased likelihood of ischemic heart disease.... read more

Baxter initiates late-stage study of novel therapy for acute kidney injury

Baxter initiates late-stage study of novel therapy for acute kidney injury

Baxter International commences a Phase 3 clinical trial assessing an investigational drug, Prismocitrate 18, that combines a citrate anticoagulant and renal replacement solution.... read more

Genetic Loci Linked to Acute Kidney Injury

Genetic Loci Linked to Acute Kidney Injury

Four single-nucleotide polymorphisms at two loci identified in discovery, replication populations.... read more

New Research Shows NEPHROCHECK Test Predicts Acute Kidney Injury Risk For Transaortic Valve Implant Patients

New Research Shows NEPHROCHECK Test Predicts Acute Kidney Injury Risk For Transaortic Valve Implant Patients

Astute Medical, Inc., developer of biomarkers for better healthcare, today said that newly published findings show that the Company's NEPHROCHECK Test may help physicians identify risk of a serious complication in patients... read more

Effect of atorvastatin on the incidence of acute kidney injury following valvular heart surgery

Effect of atorvastatin on the incidence of acute kidney injury following valvular heart surgery

Statins, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors have the potential to reduce acute kidney injury (AKI) after cardiac surgery through their pleiotropic properties. Here we studied the preventive... read more

Earlier Renal Replacement Therapy for AKI? Not So Fast, Says Dr Berns

Earlier Renal Replacement Therapy for AKI? Not So Fast, Says Dr Berns

The AKIKI study was published in the New England Journal of Medicine; ELAIN was published in JAMA. If you have not read them, you should, if for no other reason than that your colleagues are likely to ask about them.... read more

Is Timing Really Everything With RRT?

Is Timing Really Everything With RRT?

For years we have been told that early interventions result in better patient outcomes. Early cardiac catheterization results in more preserved myocardial function.... read more

Utilising the immune system in the fight against sepsis – On Medicine

Utilising the immune system in the fight against sepsis – On Medicine

In this blog, Dr. Naoshi Takeyama, Senior Editor of Journal of Intensive Care, discusses about how knowledge of immuno-oncology can also be applied to strategies for managing sepsis and severe trauma.... read more