Tag: ARDS
Acute Respiratory Failure in COVID-19: Typical ARDS?
COVID-19 is highly infectious and can lead to fatal comorbidities especially ARDS. There are currently no recommended specific anti-COVID-19 treatments, so supportive treatment is important. Fully understanding the characteristics... read more
Prevention and Treatment of ALI with Time-controlled Adaptive Ventilation
Neither the current lung protect and rest nor open lung approach (OLA) ventilation strategies have been effective at reducing VILI and ARDS-related mortality below that in the ARMA study. For a protective ventilation strategy... read more
High Risk of Thrombosis in Patients with Severe COVID-19
Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications. Higher anticoagulation targets than in usual critically ill patients should therefore... read more
Rapid Development of an Inactivated Vaccine Candidate for COVID-19
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. There are currently no SARS-CoV-2-specific... read more
On the Front Lines in Fight Against COVID-19
As a worldwide pandemic washes over the St. Louis region, the Washington University Medical Campus is eerily quiet. Most visitors, students, staff and research faculty are no longer on campus. Limited patients come to its... read more
COVID-19 Patients with Respiratory Failure: What Can We Learn From Aviation Medicine?
Patients with COVID-19 may present to hospitals and emergency medical services with an atypical form of acute respiratory distress syndrome (ARDS). Although anecdotal, a common clinical pattern has emerged, with a remarkable... read more
Trying Not to Intubate Early & Why ARDSnet may be the Wrong Ventilator Paradigm
Many of us have been working under the paradigm that COVID-19 PNA eventually develops into ARDS in the sickest patients. It appears to me that these patients don’t fit into this paradigm. Many have normal to high compliance... read more
Management of COVID-19 Respiratory Distress
Acute respiratory distress syndrome (ARDS) can originate from either the gas or vascular side of the alveolus. Although the portal for coronavirus disease 2019 (COVID-19) is inhalational, and alveolar infiltrates are commonly... read more
COVID-19 Pneumonia: ARDS or Not?
Even though it can meet the ARDS Berlin definition, the COVID-19 pneumonia is a specific disease with peculiar phenotypes. Its main characteristic is the dissociation between the severity of the hypoxemia and the maintenance... read more
Pediatric Airway Management in COVID-19 Patients
The severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic has challenged medical systems and clinicians globally to unforeseen levels. COVID-19's rapid spread has forced clinicians to care for patients with... read more
Is COVID-19 ARDS?
Acute respiratory distress syndrome (ARDS) is a heterogeneous disease. It presents with a wide range of severity, varying degrees of hypoxemia and varying degrees of pulmonary mechanical impairment. Failure of hypoxemic vasoconstriction... read more
How COVID-19 Causes ARDS
As the COVID-19 outbreak continues, we're learning more about the disease, what it does to the body and the damage it causes. Although many people with COVID-19 have no symptoms or only mild symptoms, a subset of patients... read more
Risk Factors Associated With ARDS and Death in Patients With COVID-19 Pneumonia in China
Older age was associated with greater risk of development of Acute Respiratory Distress Syndrome (ARDS) and death likely owing to less rigorous immune response. Although high fever was associated with the development of ARDS,... read more
Plasma Transfusion Shows Promise for COVID-19 Treatment
Donor blood plasma from people who have recovered from COVID-19 appears to work as a treatment for the virus, a new analysis has revealed. In this preliminary uncontrolled case series of 5 critically ill patients with... read more
Clinical Utility and Technique for Lung Ultrasound in COVID-19 Cases
Since the outbreak of a novel coronavirus in Wuhan in December 2019 and its subsequent evolution to a pandemic in March 2020, there has been growing interest in the utility of lung ultrasound in the workup and management... read more
Focus on Clinical Trial Interpretation
In a recently published meta-epidemiological study of 604 randomised clinical trials (RCTs) published between 1977 and 2018 from 53 Cochrane systematic reviews in critical care, less than 7% of the RCTs had overall low risk... read more
Lung Ultrasonography Features of COVID-19 Pneumonia
As lung abnormalities may develop before clinical manifestations and nucleic acid detection, experts have recommended early chest computerized tomography (CT) for screening suspected patients. The high contagiousness... read more
WHO Declares the Coronavirus Outbreak a Pandemic
The World Health Organization on Wednesday declared the rapidly spreading coronavirus outbreak a pandemic, acknowledging what has seemed clear for some time — the virus will likely spread to all countries on the globe. Director-General... read more
ARDS Diagnosis May Be Underrecognized
The February 27, 2020 Department of Internal Medicine Medical Grand Rounds "Acute Respiratory Distress Syndrome (ARDS),” was presented by Marc Moss, MD, Roger S. Mitchell Professor of Medicine; head, Division of Pulmonary... read more
Instrumental Activities of Daily Living Related to ARDS Survivors’ Quality of Life
Instrumental Activities of Daily Living (IADL), not body functions & structures measures, are related to ARDS survivors' quality of life and should be included in future studies. Bringing greater consistency to outcomes... read more
Respiratory Support for Patients with COVID-19 Infection
Coronavirus disease 2019 (COVID-19) has affected more than 50 countries so far this year. Xiaobo Yang and colleagues described in their single-centered, retrospective, observational study that 52 of 710 patients with confirmed... read more
Flow-controlled Ventilation Enhances Lung Aeration
Lung-protective ventilation for acute respiratory distress syndrome (ARDS) aims for providing sufficient oxygenation and carbon dioxide clearance, while limiting the harmful effects of mechanical ventilation. This study... read more
