Pediatric Airway Management in COVID-19 Patients

Pediatric Airway Management in COVID-19 Patients

The severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic has challenged medical systems and clinicians globally to unforeseen levels. COVID-19's rapid spread has forced clinicians to care for patients with... read more

Is COVID-19 ARDS?

Is COVID-19 ARDS?

Acute respiratory distress syndrome (ARDS) is a heterogeneous disease. It presents with a wide range of severity, varying degrees of hypoxemia and varying degrees of pulmonary mechanical impairment. Failure of hypoxemic vasoconstriction... read more

How COVID-19 Causes ARDS

How COVID-19 Causes ARDS

As the COVID-19 outbreak continues, we're learning more about the disease, what it does to the body and the damage it causes. Although many people with COVID-19 have no symptoms or only mild symptoms, a subset of patients... read more

Risk Factors Associated With ARDS and Death in Patients With COVID-19 Pneumonia in China

Risk Factors Associated With ARDS and Death in Patients With COVID-19 Pneumonia in China

Older age was associated with greater risk of development of Acute Respiratory Distress Syndrome (ARDS) and death likely owing to less rigorous immune response. Although high fever was associated with the development of ARDS,... read more

Plasma Transfusion Shows Promise for COVID-19 Treatment

Plasma Transfusion Shows Promise for COVID-19 Treatment

Donor blood plasma from people who have recovered from COVID-19 appears to work as a treatment for the virus, a new analysis has revealed. In this preliminary uncontrolled case series of 5 critically ill patients with... read more

Clinical Utility and Technique for Lung Ultrasound in COVID-19 Cases

Clinical Utility and Technique for Lung Ultrasound in COVID-19 Cases

Since the outbreak of a novel coronavirus in Wuhan in December 2019 and its subsequent evolution to a pandemic in March 2020, there has been growing interest in the utility of lung ultrasound in the workup and management... read more

Focus on Clinical Trial Interpretation

Focus on Clinical Trial Interpretation

In a recently published meta-epidemiological study of 604 randomised clinical trials (RCTs) published between 1977 and 2018 from 53 Cochrane systematic reviews in critical care, less than 7% of the RCTs had overall low risk... read more

Lung Ultrasonography Features of COVID-19 Pneumonia

Lung Ultrasonography Features of COVID-19 Pneumonia

As lung abnormalities may develop before clinical manifestations and nucleic acid detection, experts have recommended early chest computerized tomography (CT) for screening suspected patients. The high contagiousness... read more

WHO Declares the Coronavirus Outbreak a Pandemic

The World Health Organization on Wednesday declared the rapidly spreading coronavirus outbreak a pandemic, acknowledging what has seemed clear for some time — the virus will likely spread to all countries on the globe. Director-General... read more

ARDS Diagnosis May Be Underrecognized

ARDS Diagnosis May Be Underrecognized

The February 27, 2020 Department of Internal Medicine Medical Grand Rounds "Acute Respiratory Distress Syndrome (ARDS),” was presented by Marc Moss, MD, Roger S. Mitchell Professor of Medicine; head, Division of Pulmonary... read more

Instrumental Activities of Daily Living Related to ARDS Survivors’ Quality of Life

Instrumental Activities of Daily Living Related to ARDS Survivors’ Quality of Life

Instrumental Activities of Daily Living (IADL), not body functions & structures measures, are related to ARDS survivors' quality of life and should be included in future studies. Bringing greater consistency to outcomes... read more

Respiratory Support for Patients with COVID-19 Infection

Respiratory Support for Patients with COVID-19 Infection

Coronavirus disease 2019 (COVID-19) has affected more than 50 countries so far this year. Xiaobo Yang and colleagues described in their single-centered, retrospective, observational study that 52 of 710 patients with confirmed... read more

Flow-controlled Ventilation Enhances Lung Aeration

Flow-controlled Ventilation Enhances Lung Aeration

Lung-protective ventilation for acute respiratory distress syndrome (ARDS) aims for providing sufficient oxygenation and carbon dioxide clearance, while limiting the harmful effects of mechanical ventilation. This study... read more

Validation of Neuromuscular Blocking Agent Use in ARDS

Validation of Neuromuscular Blocking Agent Use in ARDS

The use of Neuromuscular Blocking Agents (NMBA) could significantly decrease mortality in moderate-to-severe acute respiratory distress syndrome (ARDS) patients and decrease the incidence of barotrauma during mechanical ventilation.... read more

Review of the Current Evidence on COVID-19 in Intensive Care

Review of the Current Evidence on COVID-19 in Intensive Care

Join Dr. David Lyness as he discusses the current evidence on COVID-19 in Intensive Care. A coronavirus is one of many viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract... read more

Imaging Changes of Severe COVID-19 Pneumonia in Advanced Stage

Imaging Changes of Severe COVID-19 Pneumonia in Advanced Stage

The imaging changes of acute stage from a case of 75-year-old male patient with severe COVID-19 pneumonia combined acute respiratory distress syndrome (ARDS), septic shock, and multiple organ dysfunction syndrome (MODS) who... read more

Respiratory Drive in the ARDS: Pathophysiology, Monitoring, and Therapeutic Interventions

Respiratory Drive in the ARDS: Pathophysiology, Monitoring, and Therapeutic Interventions

Neural respiratory drive, i.e., the activity of respiratory centres controlling breathing, is an overlooked physiologic variable which affects the pathophysiology and the clinical outcome of acute respiratory distress syndrome... read more