Flow-controlled Ventilation Enhances Lung Aeration

Flow-controlled Ventilation Enhances Lung Aeration

Lung-protective ventilation for acute respiratory distress syndrome (ARDS) aims for providing sufficient oxygenation and carbon dioxide clearance, while limiting the harmful effects of mechanical ventilation. This study... read more

Validation of Neuromuscular Blocking Agent Use in ARDS

Validation of Neuromuscular Blocking Agent Use in ARDS

The use of Neuromuscular Blocking Agents (NMBA) could significantly decrease mortality in moderate-to-severe acute respiratory distress syndrome (ARDS) patients and decrease the incidence of barotrauma during mechanical ventilation.... read more

Review of the Current Evidence on COVID-19 in Intensive Care

Review of the Current Evidence on COVID-19 in Intensive Care

Join Dr. David Lyness as he discusses the current evidence on COVID-19 in Intensive Care. A coronavirus is one of many viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract... read more

Imaging Changes of Severe COVID-19 Pneumonia in Advanced Stage

Imaging Changes of Severe COVID-19 Pneumonia in Advanced Stage

The imaging changes of acute stage from a case of 75-year-old male patient with severe COVID-19 pneumonia combined acute respiratory distress syndrome (ARDS), septic shock, and multiple organ dysfunction syndrome (MODS) who... read more

Respiratory Drive in the ARDS: Pathophysiology, Monitoring, and Therapeutic Interventions

Respiratory Drive in the ARDS: Pathophysiology, Monitoring, and Therapeutic Interventions

Neural respiratory drive, i.e., the activity of respiratory centres controlling breathing, is an overlooked physiologic variable which affects the pathophysiology and the clinical outcome of acute respiratory distress syndrome... read more

Ventilatory Support and Mechanical Properties of the Fibrotic Lung Acting as a “Squishy Ball”

Ventilatory Support and Mechanical Properties of the Fibrotic Lung Acting as a “Squishy Ball”

The management of the patient with lung fibrosis in the ICU is a challenge for the intensivist. The lack of studies defining the mechanical ventilation strategy, and the different underlying etiologies, make it difficult... read more

WHO Guidelines Regarding Fluid Administration for Coronarvirus Are Dangerously Misguided

WHO Guidelines Regarding Fluid Administration for Coronarvirus Are Dangerously Misguided

Portions of the current WHO guidelines regarding fluid management are dangerously misguided. The first two recommendations suggest limiting fluid administration in patients with ARDS and patients who aren't shocked, to... read more

Prone Positioning Monitored by Electrical Impedance Tomography in Patients with Severe ARDS on VV-ECMO

Prone Positioning Monitored by Electrical Impedance Tomography in Patients with Severe ARDS on VV-ECMO

Prone positioning (PP) during veno-venous ECMO is feasible, but its physiological effects have never been thoroughly evaluated. Our objectives were to describe, through electrical impedance tomography (EIT), the impact of... read more

Clinical Features of Patients Infected with Coronavirus in Wuhan, China

Clinical Features of Patients Infected with Coronavirus in Wuhan, China

A cohort of 41 patients with laboratory-confirmed 2019-nCoV infection. Patients had serious, sometimes fatal, pneumonia and were admitted to the designated hospital in Wuhan, China, by Jan 2, 2020. Clinical presentations... read more

Clinical Decision Support Systems: Future or Present in ICU?

Clinical Decision Support Systems: Future or Present in ICU?

Clinical decision support systems (CDSS) are today, a reality. More complex, useful systems will be developed in the near future, forging CDSS an essential part of ICU monitoring. However, we need to understand the algorithms... read more

Neonatal Lung Ultrasonography

Neonatal Lung Ultrasonography

This book presents lung ultrasound as an accurate, reliable, low-cost and simple imaging technique, which poses no risk of radiation damage, making bedside use both feasible and convenient in neonatal wards. The aim of... read more

Approaches to EOL Decision-making For Patients Affected by Sepsis and ARDS

Approaches to EOL Decision-making For Patients Affected by Sepsis and ARDS

A Qualitative Study of Patients With Acute Respiratory Distress Syndrome (ARDS) and Sepsis and Their Surrogates. The purpose of this study was to develop hypotheses of patient and surrogate's rationale for decision-making. Patients... read more

Risk Factors for the Development of ARDS in Mechanically Ventilated Adults in Peru

Risk Factors for the Development of ARDS in Mechanically Ventilated Adults in Peru

In this study of mechanically ventilated patients, 31% of study participants had acute respiratory distress syndrome (ARDS) at some point during their ICU stay. Optimal lung-protective ventilation was not used in a majority... read more

Study Suggests Benefits of Vitamin C for Severe Sepsis

Study Suggests Benefits of Vitamin C for Severe Sepsis

More than 1.7 million Americans develop sepsis every year and incidence of the condition is on the rise. In severe cases, widespread inflammation leads to multiorgan failure and death. Results of a new study hold... read more