Managing the Cerebral Complications of ARDS

Acute respiratory distress syndrome (ARDS) comprises 10–30% of critical care admissions worldwide. ARDS outcomes have improved secondary to ventilatory strategies that may potentially mitigate ventilator-induced lung injury.... read more

Managing the Cerebral Complications of ARDS

ARDS Guidelines: Oceans Apart or Rivers That Merge?

The updated guidelines from the ATS and ESICM reached overwhelmingly similar conclusions. Both sets of guidelines emphasize the challenges in issuing blanket recommendations that apply to all patients with ARDS, and both... read more

ARDS Guidelines: Oceans Apart or Rivers That Merge?

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the COVID-19 pandemic, and offers practical information on how to manage them. Older... read more

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

Omadacycline Treatment of Severe Pneumonia Complicated with ARDS During COVID-19

Metagenomic next-generation sequencing (mNGS) has a significant value in the diagnosis of Chlamydia psittaci infection. Timely treatment of omadacycline can improve prognosis and provide a promising new option for the treatment... read more

Omadacycline Treatment of Severe Pneumonia Complicated with ARDS During COVID-19

Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU

We analyzed unvaccinated critically ill ICU patients with COVID-19 and interpreted their demographics, clinical characteristics, comorbidities, and laboratory data upon ICU admission for a better understanding of their impact... read more

Clinical Outcomes in Critically Ill COVID-19 Unvaccinated Patients Admitted to the ICU

Extracorporeal Life Support for Adults

This book presents a concise, evidence-based review of extracorporeal life support (ECLS) for adult diseases. It describes the use of ECLS with patients who are experiencing severe hypoxemic respiratory failure (ARDS and... read more

Extracorporeal Life Support for Adults

Heat Shock Protein 27 in COVID-19 and non-COVID ARDS Pathogenesis

Acute respiratory distress syndrome (ARDS) is a common cause of hypoxemic respiratory failure in intensive care units that has increased dramatically as a result of the COVID-19 pandemic. In both COVID-19 and non-COVID... read more

Heat Shock Protein 27 in COVID-19 and non-COVID ARDS Pathogenesis

Oxygenation Improvement in Hyperinflammatory Ovine ARDS Treated with Methylprednisolone

Early and persistent improvement in oxygenation was seen only in hyperinflammatory ovine ARDS treated with methylprednisolone, while hemodynamic situation and survival was improved in both injury models and corticosteroid... read more

Oxygenation Improvement in Hyperinflammatory Ovine ARDS Treated with Methylprednisolone

Uncovering Heterogeneity in Sepsis

Among critically ill patients with sepsis, subtype strategies using clinical, biomarker, and transcriptomic data do not identify comparable patient populations and are likely to reflect disparate clinical characteristics... read more

Uncovering Heterogeneity in Sepsis

Genetic Causal Factors of ARDS

This comprehensive study highlights the importance of utilizing the MR-pheWAS framework in unraveling the complex etiology and pathogenesis of ARDS, and further underlines the value of integrating blood-based biomarkers into... read more

Genetic Causal Factors of ARDS

Inflammatory Subphenotypes in Patients at Risk of ARDS

We identified hyper- and non-hyperinflammatory subphenotypes in patients at risk of ARDS upon presentation to the emergency department. These subphenotypes remained identifiable over time and a hyperinflammatory subphenotype... read more

Inflammatory Subphenotypes in Patients at Risk of ARDS

Convalescent Plasma Cuts Death by 10% in COVID Patients on Mechanical Ventilation

A randomized clinical trial in Belgium finds that convalescent plasma reduces death rates by about 10% in COVID-19 patients requiring invasive mechanical ventilation. University of Liege researchers led the open-label... read more

Convalescent Plasma Cuts Death by 10% in COVID Patients on Mechanical Ventilation

HFNC vs. CPAP in COVID-19 Patients with ARDS in ICU

Acute hypoxic respiratory failure in coronavirus disease 2019 (COVID-19) pneumonia has been treated with oxygen delivered by oxygen masks and non-invasive ventilation (NIV) with continuous positive airway pressure (CPAP),... read more

HFNC vs. CPAP in COVID-19 Patients with ARDS in ICU

Back To The Future: ARDS Guidelines

In June 2023, Intensive Care Medicine published the European Society of Intensive Care Medicine (ESICM) practical guidelines for respiratory support in patients with acute respiratory distress syndrome (ARDS). This monumental... read more

Back To The Future: ARDS Guidelines

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

The study revealed that the utilization of non-ICU sophisticated ventilators was linked to a higher mortality rate when compared to standard ICU ventilators in COVID-19 patients with ARDS. However, given the shortage and... read more

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

During the COVID-19 pandemic, healthcare delivery was affected in various ways. For example, acute and chronic cardiovascular diseases (CVDs) and events were less frequently observed in hospitals, both because public health... read more

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

Fluid Therapy for Critically Ill Adults with Sepsis

Fluids are an important component of treating patients who are critically ill with sepsis. Although optimal fluid management in patients with sepsis remains uncertain, clinicians should consider the risks and benefits of... read more

Fluid Therapy for Critically Ill Adults with Sepsis

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone... read more

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Mechanical Ventilation in Emergency Medicine

This book discusses mechanical ventilation in emergency settings, covering the management of patients from the time of intubation until transfer to the ICU. It provides an introduction to key concepts of physiology pertinent... read more

Mechanical Ventilation in Emergency Medicine

Barotrauma Rate Is 25% in ARDS Patients Receiving ECMO

Patients with acute respiratory distress syndrome (ARDS) receiving mechanical ventilation have a high risk of barotrauma, which often has poor prognosis and high mortality. Although ECMO should theoretically protect patients... read more

Barotrauma Rate Is 25% in ARDS Patients Receiving ECMO

Acute Respiratory Distress Syndrome

This book covers all clinical aspects of acute respiratory distress syndrome (ARDS), from definition to treatment, focusing on the more recent recommendations and evidence-based medicine. The addressed topics are the... read more

Acute Respiratory Distress Syndrome

Cardiovascular Subphenotypes in ARDS

Latent class analysis (LCA) of transthoracic echocardiography (TTE) parameters identified four cardiovascular subphenotypes in acute respiratory distress syndrome (ARDS) that more closely aligned with circulatory failure... read more

Cardiovascular Subphenotypes in ARDS