Life After the Pump: Quality of Life in Cardiac Surgery Survivors

Researchers have conducted a major study—the largest of its kind for this specific population—investigating the long-term quality of life (QoL) for patients who survived post-cardiotomy cardiogenic shock (PC-CS). By... read more

VV-ECMO Wins Big: Twice the Survival Odds Over VA-ECMO in Respiratory Failure

A PRISMA-guided systematic review and meta-analysis of 11 studies involving 3,598 patients with severe respiratory failure found that veno-venous ECMO (VV-ECMO) is linked to significantly better survival to hospital discharge... read more

The Dual Deception: Amlodipine and Baclofen Overdose Mimics Brain Death and Triggers Cardiogenic Shock

This case study highlights the profound diagnostic challenge and dramatic presentation of a combined-drug overdose involving amlodipine and baclofen, a novel and previously unreported toxicological combination. Toxicological... read more

Critical Care Ultrasonography Usage in the Management of Cardiogenic Shock

Despite advancements in treatment, cardiogenic shock (CS) still has a very high mortality rate. To improve patient outcomes, a timely diagnosis and the correct management are crucial. This is especially true given the changing... read more

oXiris Treatment Efficacy To Reduce Endotoxin Levels

In this pilot study of patients with CS requiring VA-ECMO, the application of an oXiris did not demonstrate a significant reduction in endotoxin levels at 48 h compared with standard care. While we observed temporal decreases... read more

Prevalence and Outcomes of Shock in Internal Medicine Patients

This retrospective observational study investigated the incidence, management, and outcomes of 125 shock patients admitted to the internal medicine department of a referral university hospital in Bangkok, Thailand, addressing... read more

Levosimendan Role in ECMO for Refractory Cardiac Arrest

Levosimendan use in extracorporeal cardiopulmonary resuscitation (ECPR) did not improve survival. Neurological outcome could be representative of the short- and long-term outcomes. Future well-designed randomized trials... read more

Early Initiated Noradrenaline vs. Fluid Therapy for Hypotension and Shock

The VASOSHOCK trial is a pragmatic, multi-center, superiority, randomized controlled trial investigating early initiation of peripheral noradrenaline in hypotension and shock, investigating the impact of this treatment on... read more

TyG Index And Short-term Mortality in Patients with Cardiogenic Shock

The triglyceride-glucose (TyG) index is significantly associated with short-term mortality in patients with cardiogenic shock (CS) and may serve as a useful biomarker for risk stratification. This retrospective cohort... read more

Diagnostic Value of Chest X-ray in Acute Pulmonary Thromboembolism

This case underscores the diagnostic value of chest X-ray in acute pulmonary thromboembolism (PTE), highlighting the significance of recognizing classical radiographic signs such as Westermark's, Palla's, Fleischner's and... read more

Vasoactive Agents in Cardiogenic Shock Related to AMI and ADHF

Cardiogenic shock (CS) is a heterogeneous condition associated with exceptionally high mortality rates, despite significant advances in the field of cardiology. The primary causes of CS are myocardial infarction-related CS... read more

Resource Utilization Associated with ECMO vs. Microaxial Flow Pump for Infarct-related Cardiogenic Shock

Microaxial flow pump was associated with lower resource utilization compared to venoarterial extracorporeal membrane oxygenation (VA-ECMO). Resource utilization should be incorporated in prospective RCTs and taken into account... read more

Management of Patients Supported with VA-ECMO

Veno-arterial extracorporeal membrane oxygenation (VA ECMO) application in adult patients has significantly increased in recent years. The Extracorporeal Life Support Organization (ELSO) registry includes more than 39,000... read more

Which Antimicrobial Treatment for Patients with Bloodstream Infection During ECMO Support?

Enterococcus sp. was incriminated in about a third of BSI among patients with ECMO support. High appropriateness would only be obtained with piperacilline/tazobactam or carbapenems in association with vancomycin while 3rd... read more

VEGFR1 Genetic Regulation During Sepsis and Association with ARDS Susceptibility

We identified biologically relevant protein quantitative trait loci (pQTLs) of vascular endothelial growth factor receptor 1 (VEGFR1) levels during sepsis in TCF20 and identified CYP2D6 as the gene more biologically implicated.... read more

ICU-AW in Cardiogenic Shock Patients Requiring Mechanical Circulatory Support

This study provides insights into the characteristics of intensive care unit-acquired weakness (ICU-AW) in patients with Cardiogenic Shock (CS) requiring mechanical circulatory support (MCS). ICU-AW frequently occurred... read more

High cDPP3 Predicts Mortality and Need for Organ Support in Cardiogenic Shock

The present study confirms that circulating dipeptidyl peptidase 3 (cDPP3) and its kinetics are associated with 30-day mortality and the need for organ support in a large and diverse population of CS. The prognostic value... read more

Veno-Arterial-Venous ECMO in a Patient Undergoing Dialysis and Having Cardiopulmonary Failure Due to COVID-19

COVID-19 can cause cardiomyopathy, a rare cardiovascular disorder that can lead to cardiogenic shock. The cardiac and respiratory symptoms may not occur simultaneously, and it is possible to switch to veno-arterial-venous... read more

ECLS in Cardiogenic Shock Complicating Acute Myocardial Infarction: Benefit and Harm

Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group. Recently, frequentist analysis showed... read more

Conservative or Liberal Oxygen Targets in Patients on VA-ECMO

In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more

Effect of Different Shock Conditions on Mesenteric Hemodynamics

The velocity parameters of SMA Doppler ultrasound such as TAMV and PSV can reflect cardiac function. The measurements of SMA RI and PI are correlated with lactate levels, having a positive predictive value for hyperlactatemia... read more

Outcomes for Mechanically Ventilated Patients with Acute Myocardial Infarction Admitted to Medical vs Cardiac ICUs

In this multicenter, national analysis of ICU admission for critically ill patients with AMI, we found that admission to the Cardiac Intensive Care Unit (CICU) was associated with lower in-hospital mortality than patients... read more