Resource Utilization Associated with ECMO vs. Microaxial Flow Pump for Infarct-related Cardiogenic Shock

Microaxial flow pump was associated with lower resource utilization compared to venoarterial extracorporeal membrane oxygenation (VA-ECMO). Resource utilization should be incorporated in prospective RCTs and taken into account... read more

Management of Patients Supported with VA-ECMO

Veno-arterial extracorporeal membrane oxygenation (VA ECMO) application in adult patients has significantly increased in recent years. The Extracorporeal Life Support Organization (ELSO) registry includes more than 39,000... read more

Which Antimicrobial Treatment for Patients with Bloodstream Infection During ECMO Support?

Enterococcus sp. was incriminated in about a third of BSI among patients with ECMO support. High appropriateness would only be obtained with piperacilline/tazobactam or carbapenems in association with vancomycin while 3rd... read more

VEGFR1 Genetic Regulation During Sepsis and Association with ARDS Susceptibility

We identified biologically relevant protein quantitative trait loci (pQTLs) of vascular endothelial growth factor receptor 1 (VEGFR1) levels during sepsis in TCF20 and identified CYP2D6 as the gene more biologically implicated.... read more

ICU-AW in Cardiogenic Shock Patients Requiring Mechanical Circulatory Support

This study provides insights into the characteristics of intensive care unit-acquired weakness (ICU-AW) in patients with Cardiogenic Shock (CS) requiring mechanical circulatory support (MCS). ICU-AW frequently occurred... read more

High cDPP3 Predicts Mortality and Need for Organ Support in Cardiogenic Shock

The present study confirms that circulating dipeptidyl peptidase 3 (cDPP3) and its kinetics are associated with 30-day mortality and the need for organ support in a large and diverse population of CS. The prognostic value... read more

Veno-Arterial-Venous ECMO in a Patient Undergoing Dialysis and Having Cardiopulmonary Failure Due to COVID-19

COVID-19 can cause cardiomyopathy, a rare cardiovascular disorder that can lead to cardiogenic shock. The cardiac and respiratory symptoms may not occur simultaneously, and it is possible to switch to veno-arterial-venous... read more

ECLS in Cardiogenic Shock Complicating Acute Myocardial Infarction: Benefit and Harm

Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group. Recently, frequentist analysis showed... read more

Conservative or Liberal Oxygen Targets in Patients on VA-ECMO

In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more

Effect of Different Shock Conditions on Mesenteric Hemodynamics

The velocity parameters of SMA Doppler ultrasound such as TAMV and PSV can reflect cardiac function. The measurements of SMA RI and PI are correlated with lactate levels, having a positive predictive value for hyperlactatemia... read more

Outcomes for Mechanically Ventilated Patients with Acute Myocardial Infarction Admitted to Medical vs Cardiac ICUs

In this multicenter, national analysis of ICU admission for critically ill patients with AMI, we found that admission to the Cardiac Intensive Care Unit (CICU) was associated with lower in-hospital mortality than patients... read more

Age and Associated Outcomes Among Patients Receiving V-A ECMO

In a multinational study using the ELSO Registry, we found that increasing age was strongly associated with higher risk of hospital mortality and complications among patients receiving V-A ECMO for cardiogenic shock, with... read more

Age and Associated Outcomes Among Patients Receiving V-A ECMO

Revisiting VA-ECMO in Infarct-related Cardiogenic Shock

Despite advances in medical therapies and coronary revascularization, infarct-related cardiogenic shock remains a life-threatening emergency with high death rates. Temporary mechanical circulatory support, including peripheral... read more

Revisiting VA-ECMO in Infarct-related Cardiogenic Shock

ECLS in Infarct-Related Cardiogenic Shock

In patients with acute myocardial infarction complicated by cardiogenic shock with planned early revascularization, the risk of death from any cause at the 30-day follow-up was not lower among the patients who received ECLS... read more

ECLS in Infarct-Related Cardiogenic Shock

Manual of Cardiac Intensive Care

Addressing the changing needs of clinicians in today’s CCU, ICU and CICU, Manual of Cardiac Intensive Care is an easy-to-use, point-of-care reference for cardiologists, intensivists, physicians, trainees, and other health... read more

Manual of Cardiac Intensive Care

Pulmonary Artery Catheter Use and Mortality in the Cardiac ICU

The appropriate use of pulmonary artery catheters (PACs) in critically ill cardiac patients remains debated. There is wide variation in the use of PACs that is not fully explained by patient level-factors and appears driven... read more

Pulmonary Artery Catheter Use and Mortality in the Cardiac ICU

Management of RV-Predominant Heart Failure and Shock in the Cardiac ICU

Cardiogenic shock from left ventricular failure is a common presentation in the intensive care unit. In contrast, right ventricular (RV)-predominant heart failure (HF) causing shock is less well recognized. We review... read more

Management of RV-Predominant Heart Failure and Shock in the Cardiac ICU

Essentials of Shock Management: A Scenario-Based Approach

This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of... read more

Essentials of Shock Management: A Scenario-Based Approach

Percutaneous vs. Surgical Cannulation for Femoro-Femoral VA-ECMO in Cardiogenic Shock Patients

Compared with surgical cannulation, percutaneous cannulation was independently associated with lower in-hospital mortality and fewer complications. Among 12,592 patients meeting study inclusion, 9,249 (73%) underwent percutaneous... read more

Percutaneous vs. Surgical Cannulation for Femoro-Femoral VA-ECMO in Cardiogenic Shock Patients

The Pulmonary Artery Catheter: A Solution Still Looking For a Problem

In 1970, Jeremy Swan, William Ganz, and colleagues published their seminal paper “Catheterization of the heart in man with use of flow-directed balloon-tipped catheter”. Few devices in our specialty have generated more... read more

The Pulmonary Artery Catheter: A Solution Still Looking For a Problem

Use of Hemoadsorption in Patients With Severe Intoxication Requiring ECMO

Drugs intoxications often lead to severe vasoplegia and cardiogenic shock, and VA-ECMO represents a viable therapy option. However, as cardiopulmonary support is not contributing to the removal of the causal agent from the... read more

Use of Hemoadsorption in Patients With Severe Intoxication Requiring ECMO