Dynamic and Hybrid Configurations for ECMO

Dynamic and Hybrid Configurations for ECMO

Dynamic or hybrid configurations for extracorporeal membrane oxygenation (ECMO) are needed when patient physiology or clinical conditions change. Dynamic configurations included configurations converting from veno-arterial... read more

Milrinone vs. Dobutamine in the Treatment of Cardiogenic Shock

Milrinone vs. Dobutamine in the Treatment of Cardiogenic Shock

In patients with cardiogenic shock, no significant difference between Milrinone and Dobutamine was found with respect to the primary composite outcome or important secondary outcomes. A total of 192 participants (96 in... read more

Managing Patients With Short-Term Mechanical Circulatory Support

Managing Patients With Short-Term Mechanical Circulatory Support

The use of mechanical circulatory support for patients presenting with cardiogenic shock is rapidly increasing. Currently, there is only limited and conflicting evidence available regarding the role of the Impella (a microaxial,... read more

Left Ventricular Unloading and ECpella Role

Left Ventricular Unloading and ECpella Role

The main reason for the emergency implantation of venoarterial extracorporeal membrane oxygenation (VA-ECMO) is the restoration of adequate systemic perfusion, while protecting the failing heart and promoting myocardial recovery... read more

Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock

Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock

PAC usage in cardiogenic shock (CS) is being revitalized by recent positive analyses of large registry and administrative databases. To realize the full potential of pulmonary artery catheters (PAC), more research is urgently... read more

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock

The clinical utilization of extracorporeal membrane oxygenation (ECMO) has seen remarkable expansion since its inception in the early 1970s, including a period of exponential growth in the United States. Venoarterial... read more

Thrombosis and Bleeding in ECMO without Anticoagulation

Thrombosis and Bleeding in ECMO without Anticoagulation

Extracorporeal membrane oxygenation (ECMO) causes both thrombosis and bleeding. Major society guidelines recommend continuous, systemic anticoagulation to prevent thrombosis of the ECMO circuit, though this may be undesirable... read more

VA-ECMO to Rescue Sepsis-induced Cardiogenic Shock

VA-ECMO to Rescue Sepsis-induced Cardiogenic Shock

Patients with sepsis-induced cardiomyopathy with cardiogenic shock have a high mortality. This study assessed venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for sepsis-induced cardiogenic shock refractory... read more

Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO

Massive PE with Intra-hospital Cardiac Arrest and Full Recovery of RV Function after vaECMO

The concept of vaECMO treatment alone might be a valuable alternative in selected patients with massive PE and cardiogenic shock, in whom thrombolytic therapy might not unload the RV fast enough. We present a case of a... read more

Potential Therapy for Improving Sudden Cardiac Arrest Resuscitation Outcomes

Potential Therapy for Improving Sudden Cardiac Arrest Resuscitation Outcomes

The severity of cardiogenic shock following asystolic cardiac arrest is dependent on the length of cardiac arrest prior to cardiopulmonary resuscitation and is mediated by myocardial stunning resulting from mitochondrial... read more

Management of Cardiogenic Shock Complicating Myocardial Infarction – 2019 Update

Management of Cardiogenic Shock Complicating Myocardial Infarction – 2019 Update

In general, randomized clinical trials in CS are difficult to perform and only three randomized trials adequately powered to detect differences in clinical outcomes achieved completion of the required number of patients. Based... read more

Lower Glucose Targets Show Improved Mortality in Cardiac Patients

Lower Glucose Targets Show Improved Mortality in Cardiac Patients

Tighter glucose control while minimizing the risk of severe hypoglycemia is associated with lower mortality among critically ill cardiac patents, new research suggests. Researchers reported in CHEST on the outcomes of... read more

Microcirculation Evolution in Patients on VA-ECMO for Refractory Cardiogenic Shock

Microcirculation Evolution in Patients on VA-ECMO for Refractory Cardiogenic Shock

Microcirculation is severely impaired in patients with refractory cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO). Inability to rapidly restore microcirculation during the first... read more

Thyroid Storm in the ICU

Thyroid Storm in the ICU

Thyroid storm requiring ICU admission causes high in-ICU mortality. Multiple organ failure and early cardiogenic shock seem to markedly impact the prognosis, suggesting a prompt identification and an aggressive management. 92... read more

Cardiogenic Shock – The Next Level & Mechanical Circulatory Support

Cardiogenic Shock – The Next Level & Mechanical Circulatory Support

We could center this discussion about the SCAI paper that came out (attached). A nice collaborative expert panel piece outlining a CS pyramid used quickly at the bedside in the ED, ICU, Cath Lab, etc to help us identify these... read more

Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock

Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock

Temporary circulatory support (TCS) have become the cornerstone of the management of patients with cardiogenic shock, although the evidence supporting their efficacy is limited. VA-ECMO is considered the first-line option,... read more

Use of Levosimendan in ICU Settings

Use of Levosimendan in ICU Settings

Levosimendan has been demonstrated to have potential utility in a range of critical illness scenarios. It must be acknowledged, however, that in each sphere of application, the evidence is incomplete or indicative rather... read more