Essentials of Shock Management: A Scenario-Based Approach

Essentials of Shock Management: A Scenario-Based Approach

This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of... read more

Resuscitation with Blood Products in Patients with Trauma-related Hemorrhagic Shock Receiving Prehospital Care

Resuscitation with Blood Products in Patients with Trauma-related Hemorrhagic Shock Receiving Prehospital Care

The trial did not show that prehospital PRBC–LyoPlas resuscitation was superior to 0·9% sodium chloride for adult patients with trauma related hemorrhagic shock. Further research is required to identify the characteristics... read more

Traumatic and Ischemic Injury: Methods and Protocols

Traumatic and Ischemic Injury: Methods and Protocols

This volume focuses on procedures for the development and application of several research animal models and in vitro methods that allow researchers to gain insight into the underlying cellular, biochemical, and physiological... read more

Thrombotic and Hemorrhagic Complications in Critically Ill Patients with COVID-19

Thrombotic and Hemorrhagic Complications in Critically Ill Patients with COVID-19

Critically ill patients with COVID-19 experience high rates of venous and arterial thrombotic complications. The rates of bleeding may be higher than previously reported and re-iterate the need for randomised trials to better... read more

The Misunderstood Coagulopathy of Liver Disease

The Misunderstood Coagulopathy of Liver Disease

In patients with abnormal coagulation testing results in the setting of liver disease, INR and PT may be best used to provide the practitioner with information about the synthetic function of the liver but not to assess hemorrhagic... read more

The Protective Effects of Regional Hypothermia on Injured Limbs Combined with Hemorrhagic-shock & Tourniquet

The Protective Effects of Regional Hypothermia on Injured Limbs Combined with Hemorrhagic-shock & Tourniquet

The aim of this study is to investigate the protective effects of regional hypothermia (RH) on rabbits' limbs injured by a steel-ball combined with hemorrhagic-shock, and then employed tourniquet over-time, tried to identify... read more

Use of Vasopressor Increases the Risk of Mortality in Traumatic Hemorrhagic Shock

Use of Vasopressor Increases the Risk of Mortality in Traumatic Hemorrhagic Shock

Use of vasopressor for traumatic hemorrhagic shock was associated with mortality after controlling for biases (trauma severity; volume of fluid resuscitation). Among 236,698 trauma patients, 3,551 were included in the... read more

Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock

Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock

In injured patients at risk for hemorrhagic shock, the prehospital administration of thawed plasma was safe and resulted in lower 30-day mortality and a lower median prothrombin-time ratio than standard-care resuscitation.... read more

Hemorrhagic Shock: Pearls and Pitfalls for the Resuscitation Room

Hemorrhagic Shock: Pearls and Pitfalls for the Resuscitation Room

Hemorrhagic shock is a state of systemic hypoperfusion secondary to acute blood loss which may have either traumatic or atraumatic etiologies. While gastrointestinal and traumatic etiologies are some of the most common causes... read more

Low-volume Resuscitation with Normal Saline is Associated with Microvascular Endothelial Dysfunction After Hemorrhage

Low-volume Resuscitation with Normal Saline is Associated with Microvascular Endothelial Dysfunction After Hemorrhage

Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids. Resuscitation with NS failed to inhibit syndecan-1... read more

Systemic and Microcirculatory Effects of Blood Transfusion in Experimental Hemorrhagic Shock

Systemic and Microcirculatory Effects of Blood Transfusion in Experimental Hemorrhagic Shock

The microvascular reperfusion injury after retransfusion has not been completely characterized. Specifically, the question of heterogeneity among different microvascular beds needs to be addressed. In addition, the identification... read more