Tag: COPD
Two Biomarkers Improve CRB-65 Predictability for Death Due to Community-Acquired Pneumonia
Augmenting CRB-65 (confusion, respiratory rate, blood pressure, and age 65 or older) score with troponin T high-sensitive (TnT-hs) and procalcitonin (PCT) help to predict death or intensive care unit (ICU) admission of patients... read more
Relationship between Concentrations of Oxygen and Levels of Oxidative Stress in Patients Receiving Oxygen Therapy for Severe COVID-19 Pneumonia
We evaluated the potential of high-flow oxygen therapy to increase oxidative stress and inflammation in COVID-19 patients. Our observation of decreased MDA levels when transitioning hypertensive patients from high-flow to... read more
Management of Refractory COPD
Chronic obstructive pulmonary disease (COPD) is a common condition with an estimated global prevalence of almost 12 percent in adults over age 30 years [1-3]. Prior to the onset of the COVID-19 (coronavirus disease 2019)... read more
Spontaneous Breathing Trials Should Be Adapted for Each Patient According To The Critical Illness
Unassisted SBTs, namely PSV0PEEP0 and T-piece trial, are the most appropriate to replicate the postextubation effort to breathe. In this multicentre randomized cross-over study, adult intensive care unit patients under... read more
Invasive Fungal Infections in Non-neutropenic Patients
Critically ill patients, particularly those with features of immunosuppression, are susceptible to invasive fungal infections (IFI), which pose significant diagnostic and therapeutic challenges. Candida and Aspergillus,... read more
COPD: Heterogeneity and Personalized Treatment
This book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented... read more
Association Between Comorbid COPD and Prognosis of Patients Admitted to ICU for Non-COPD Reasons
Comorbid COPD increased the risk of 28-day mortality among patients admitted to the ICU for non-COPD reasons, especially for those admitted to the cardiac surgery recovery unit. A retrospective cohort study was performed... read more
Optimal Antibiotic Treatment Duration of Upper and Lower Respiratory Tract Infections
The available evidence for non-ICU community-acquired pneumonia (CAP) and chronic obstructive pulmonary disease (AECOPD) supports a short-course treatment duration of 5 days in patients who have clinically improved. Efforts... read more
Comorbid Burden at ICU Admission in COVID-19 vs. Sepsis and ARDS
The burden of age and comorbidity is more prominent in ICU-admission for sepsis and acute respiratory distress syndrome (ARDS) than for COVID-19. This is likely to be caused by a combination of COVID-19 affecting the relatively... read more
COVID-19 ARDS Patients vs. Patients with ARDS
Ventilation management may differ between COVID–19 ARDS (COVID–ARDS) patients and patients with pre–COVID ARDS (CLASSIC–ARDS); it is uncertain whether associations of ventilation management with outcomes for CLASSIC–ARDS... read more
Glucose Metabolism Disorders: Pre-hospital Oxygen Therapy and Saturation Variability in COVID-19 Patients
The COVID-19 pandemic has revealed that viruses can have multiple receptor properties, penetrating various tissues and causing mutations in various genes, thus promoting a range of metabolic disorders. The purpose of... read more
Risk Factors of Post-intubation Hypotension in Severe Pneumonia Patients
Post-intubation hypotension (PIH) was one of the serious complications after Endotracheal intubation (ETI) in Severe pneumonia (SP) patients. The risk factors of PIH were investigated in SP patients to provide a theoretical... read more
Two weaning strategies for NIV in COPD patients with ARF
Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more
Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease
Procalcitonin level, pneumothorax, neutrophil count at 14 days, and hemoglobin level at 14 days after admission were poor prognostic indicators among patients with NCPD-PJP. Neutrophil count was related with poor prognosis... read more
Proposal for a 4-Level Classification System of Severe COPD Exacerbation According to Healthcare Resource Utilization
The definition of an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD) has been modified several times the last decade in Global Initiative for COPD (GOLD) recommendations. According to the updated GOLD... read more
