Tag: coronavirus
Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
The mRNA-1273 vaccine showed 94.1% efficacy at preventing COVID-19 illness, including severe disease. Aside from transient local and systemic reactions, no safety concerns were identified. The trial enrolled 30,420 volunteers... read more
The Risk of False Negative Results with the Curative COVID-19 Test
The U.S. Food and Drug Administration (FDA) is alerting patients and health care providers of the risk of false results, particularly false negative results, with the Curative SARS-Cov-2 test. Risks to a patient of a... read more
FDA Warns Against Cutting the COVID-19 Vaccine Dosing in Half
The Food and Drug Administration (FDA) is warning health care workers that any changes to the authorized dosing schedules of COVID-19 vaccines currently being administered would significantly place public health at risk and... read more
Understanding Moral Injury
The Understanding Moral Injury video was put together by the LTLC-Critical Care programme. This is an HEE and NHSEI initiative aimed at supporting the cross-skilling of the London NHS workforce to manage existing and spikes... read more
The Evolving Armamentarium of COVID-19 Therapeutics
Multiple repositories have been created for the vast scientific outpouring of COVID-19 research. The NIH regularly updates its treatment guidelines, which will be the primary reference for this review. To cut to the... read more
Unexpectedly High Frequency of Enterococcal Bloodstream Infections in COVID-19 Patients Admitted to an Italian ICU
Coronavirus disease 2019 seemed to increase the frequency of bloodstream infections (particularly Enterococcus-related bloodstream infection) after ICU admission. This may have been due to enteric involvement in patients... read more
Ivermectin for COVID-19, Breakthrough Treatment or Hydroxychloroquine Redux?
It’s an indisputable fact that we need better treatments for COVID-19. This is particularly true in the outpatient setting. Let’s count how many we have today, hmm, this shouldn’t take long. That would be zero —... read more
Pfizer and BioNTech Speed Up Timeline for COVID-19 Vaccine
Pfizer and its partner BioNTech plan to offer their Covid-19 vaccine to any clinical trial volunteer who received placebo by March 1, several months earlier than initially planned. The decision represents the conclusion... read more
Ten reasons why corticosteroid therapy reduces mortality in severe COVID-19
Primary outcome in the RECOVERY trial and in the WHO REACT meta-analysis was 28-day mortality. Assessing 28-day mortality may not be the optimal outcome in a trial. Since patients with severe COVID-19 often require prolonged... read more
COVID-19 – In The Eye Of The Storm
We're back in the eye of the storm, said NHS Chief Executive Sir Simon Stevens. Yes we are. He made no admission of how we got into this storm, nor explained how we’re going to get out of it. His Five Year Plan for the... read more
The COVID-19 Vaccine: An Expert’s Medical Guide for All
Vaccine expert Zeil Rosenberg, M.D. shares his medical knowledge, backed by scientific data, about the development, safety and effectiveness of the new COVID-19 vaccines. Dr. Rosenberg M.D. is a Board-Certified Preventive... read more
COVID-19 Diagnosis and Prognosis Using the Urine Foaming Test
Urine foaming test (UFT) is useful, particularly in predicting the clinical severity of COVID-19. The UFT could be recommended as a point of care test, rapid and non-invasive method in the diagnosis and follow-up of COVID-19. A... read more
Support and Follow-up Needs of Patients Discharged from ICU After Severe COVID-19
After discharge from an intensive care unit(ICU), over 50% of patients face significant physical, mental and cognitive problems. The COVID-19 pandemic has resulted in a large cohort of these patients who will need follow-up... read more
Nutritional Risk Screening and Body Composition in COVID-19 Patients
Present findings confirm the clinical utility of NRS-2002 to assess nutritional risk in patients with COVID-19 at hospital admission and in predicting LOS, and that bioimpedance does not seem to add further predictive value.... read more
From the Exposome to the Socioexposome in COVID-19 Research
The coronavirus disease 2019 (COVID-19) pandemic continues to expose how access to health care and delivery of care are important concerns, second only to the primary concern regarding exposure to the severe acute respiratory... read more
Medical officials use new tool for COVID patients
The Barren-Metcalfe County Emergency Medical Service will soon implement a new medical device that will benefit COVID-19 patients as well as emergency medical personnel. The medical device, the Sea-Long helmet, is a clear,... read more
Patient Characteristics Associated With Telemedicine Access During the COVID-19 Pandemic
In this cohort study of patients scheduled for primary care and medical specialty ambulatory telemedicine visits at a large academic health system during the early phase of the COVID-19 pandemic, older patients, Asian patients,... read more
Extracorporeal Membrane Oxygenation for COVID-19
The coronavirus disease 2019 (COVID-19) pandemic has placed extraordinary strain on global healthcare systems. Use of extracorporeal membrane oxygenation (ECMO) for patients with severe respiratory or cardiac failure attributed... read more
Harmonizing Heterogeneous Endpoints in COVID-19 Trials Without Loss of Information
All ongoing clinical trials should include a stacked probability plot in their statistical analysis plan as descriptive analysis. While primary analysis should be on an early endpoint with appropriate capability to be... read more
