Tag: coronavirus
Effect of Tocilizumab vs. Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia
The administration of tocilizumab in patients with COVID-19 pneumonia and a Pao2/Fio2 ratio between 200 and 300 mm Hg did not reduce the risk of clinical worsening. Further blinded, placebo-controlled randomized clinical... read more
Critical Care Beds Are No Use Without Enough Specialist Staff
In 2020 there have been announcements of the expansion of critical care capacity across the NHS, while at the same time headlines have detailed stories of hospitals running out of critical care beds. And this week dire warnings... read more
Lung Histopathology in COVID-19 as Compared to SARS and H1N1 Influenza
Diffuse alveolar damage (DAD) was reported in 88% of patients with COVID-19. This is similar to both H1N1 (90%) and SARS (98%). Pulmonary microthrombi was reported in 57% of patients with COVID-19. This was similar to... read more
Panel Provides a Look at the Fast-changing Science of COVID-19 Diagnosis, Therapy, and Prevention
As the pace of research related to COVID-19 continues at an unprecedented rate, clinicians on the front line of the pandemic are challenged to keep up with a deluge of information to ensure they are bringing best practices... read more
Implantation of Impella CP Left Ventricular Assist Device Under the Guidance of 3D Intracardiac Echocardiography
Three-dimensional intracardiac echocardiography is a feasible option to guide implantation of the Impella CP for left ventricular mechanical support and should be carefully considered in cases where other imaging modalities... read more
Some Signs of Recovery From Severe COVID-19 Lung Damage
In two early studies, researchers said some patients showed signs of healing just weeks after leaving the hospital. Lingering shortness of breath and diminished stamina have dogged many COVID patients whose lungs were... read more
Dr. Fauci Headlines COVID-19-focused Opening Session at CHEST 2020
The COVID-19 pandemic upended the practices and lives of CHEST members—and changed CHEST 2020 into a virtual meeting—so it's fitting that this year's Opening Session focused on the defining global event of the year. Anthony... read more
Ultrasound Teleguidance to Reduce Healthcare Worker Exposure to COVID-19
The recent expansion of telemedicine during the coronavirus disease 2019 (COVID-19) pandemic is likely to continue based on the Food and Drug Administration's new guidelines supporting remote monitoring technologies as a... read more
Balancing Intervention and Inaction During the COVID-19 Pandemic
More than 38 million people worldwide have been infected with the severe acute respiratory syndrome (SARS) coronavirus 2, creating intense pressure on clinicians to offer state-of-the-art, life-saving treatment to patients. The... read more
Synthesis and Systematic Review of Reported Neonatal COVID-19 Infections
A number of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections have been reported in neonates. Here, we aim to clarify the transmission route, clinical features and outcomes of these infections. We present... read more
The Effectiveness of 8 Nonpharmaceutical Interventions Against COVID-19 in 41 Countries
Governments are attempting to control the COVID-19 pandemic with nonpharmaceutical interventions (NPIs). However, it is still largely unknown how effective different NPIs are at reducing transmission. Data-driven studies... read more
Outcomes of Neonates Born to Mothers With Severe COVID-19
In this cohort study, no evidence of vertical transmission of SARS-CoV-2 was identified in the first 101 newborns born to mothers positive for or with suspected SARS-CoV-2 infections at a large medical center in an epicenter... read more
Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy
To the best of our knowledge, this is the first multicenter study that prospectively evaluated the benefits and the role of HFNO combined with awake prone positioning in the prevention of intubation in an adjusted large cohort... read more
VTE and COVID-19: Would you like to know more?
Who wouldn't want to know more about a disease that has killed >1 million people to date, worldwide. Who wouldn't want to know more about the thromboembolic risk associated with COVID-19 when we have been told that the VTE... read more
Factors Associated to ICU Mortality in Critically Ill Patients Infected with COVID-19 in Spain
Older COVID-19 patients with higher APACHE II scores on admission, those who developed AKI grades II or III and/or septic shock during ICU stay had an increased risk-of-death. ICU mortality was 31%. A total of 663 patients... read more
Extracorporeal Cytokine Adsorption as an Alternative to Pharmacological Inhibition of IL-6 in COVID-19
With great interest we read the article by Convertino et al. discussing potential treatment targets for pharmacological immunomodulation in coronavirus disease 2019 (COVID-19) with acute respiratory distress syndrome (ARDS).... read more
Clinical Communication with Families in the Age of COVID-19
The admission of a critically ill patient to an intensive care unit (ICU) is a distressing event for the patient, their family and friends, which has been amplified by the impact of the covid-19 pandemic. Many hospitals... read more
Endothelial Dysfunction Role During COVID-19
Emerging data suggest a crucial role of endothelial dysfunction during SARS-CoV-2 infection, as a direct target of the virus and inflammatory cytokines as well as the main actor in orchestrating a pro-inflammatory and pro-coagulant... read more
FDA Authorized First Point-of-Care Antibody Test for COVID-19
U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the first serology (antibody) point-of-care (POC) test for COVID-19. The Assure COVID-19 IgG/IgM Rapid Test Device was first authorized for... read more
