Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19

Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19

Treatment with convalescent plasma compared with placebo or standard of care was not significantly associated with a decrease in all-cause mortality or with any benefit for other clinical outcomes. The certainty of the evidence... read more

Learning From Doctors with Long COVID-19

Learning From Doctors with Long COVID-19

When Sarah Burns and Sue Warren started a support group for doctors with long covid, they found a number of people struggling with new experiences, losses, and vulnerabilities Long covid has emerged as a serious, yet poorly... read more

They served on the COVID-19 front lines. Now these emergency medicine doctors can’t find jobs.

They served on the COVID-19 front lines. Now these emergency medicine doctors can’t find jobs.

Usually, emergency medicine residents fend off recruiters hoping to hire them. This year, they’re barely getting calls back. Here's how COVID-19 has upended EM job prospects — and what these young doctors worry they may... read more

Helmet CPAP to treat hypoxic pneumonia outside the ICU

Helmet CPAP to treat hypoxic pneumonia outside the ICU

Respiratory failure due to COVID-19 pneumonia is associated with high mortality and may overwhelm health care systems, due to the surge of patients requiring advanced respiratory support. Shortage of intensive care unit... read more

Causes and Timing of Death in Critically Ill COVID-19 Patients

Causes and Timing of Death in Critically Ill COVID-19 Patients

Mortality rate of critically ill COVID-19 patients is high, especially in those requiring invasive mechanical ventilation. However, the causes and the timing of death of patients admitted to the ICU for SARS-CoV-2 pneumonia... read more

Analysis of Fentanyl Pharmacokinetics and Tolerance in Critically-Ill Children

Analysis of Fentanyl Pharmacokinetics and Tolerance in Critically-Ill Children

Different weight-based fentanyl dosing rates may be required for infants and children of different ages to achieve similar plasma concentrations. Using SBS scores may guide the dosing titration of fentanyl that resulted in... read more

SOFA Score Accuracy For Determining Mortality Of Severely Ill Patients With COVID-19 Pneumonia

SOFA Score Accuracy For Determining Mortality Of Severely Ill Patients With COVID-19 Pneumonia

The SOFA score possesses inadequate discriminant accuracy to be used for ventilator triage of COVID-19 patients. A better option is needed that incorporates variables specifically related to mortality in patients with COVID-19... read more

Testing Asymptomatic Patients for COVID-19 – Known Unknowns

Testing Asymptomatic Patients for COVID-19 – Known Unknowns

How common is asymptomatic COVID-19? How infectious is it? And how much does it actually contribute to overall transmission? Nicola Low spoke on behalf of herself and Muge Cevik to outline the role of asymptomatic transmission.... read more

Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients

Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients

The COVID-19 pandemic is responsible for many hospitalizations in intensive care units (ICU), with widespread use of invasive mechanical ventilation (IMV) which exposes patients to the risk of ventilator-associated pneumonia... read more

Central and peripheral nervous system complications of COVID-19

Central and peripheral nervous system complications of COVID-19

CNS and PNS complications were common in hospitalized COVID-19 patients, particularly in the ICU, and often attributable to critical illness. When COVID-19 was the primary cause for neurological disease, no signs of viral... read more

Duty of Care: One NHS Doctor’s Story of Courage and Compassion on the COVID-19 Frontline

Duty of Care: One NHS Doctor’s Story of Courage and Compassion on the COVID-19 Frontline

The first book to tell the full story of the Covid-19 pandemic, from an NHS doctor working inside hospitals to save lives and combat the virus on the front line. Duty of Care is the first book to tell the full story of... read more

Effect of a Single High Dose of Vitamin D3 on Hospital LOS in Patients with COVID-19

Effect of a Single High Dose of Vitamin D3 on Hospital LOS in Patients with COVID-19

Among hospitalized patients with COVID-19, a single high dose of vitamin D3, compared with placebo, did not significantly reduce hospital length of stay. The findings do not support the use of a high dose of vitamin D3 for... read more

The Plague Cycle: The Unending War Between Humanity and Infectious Disease

The Plague Cycle: The Unending War Between Humanity and Infectious Disease

For four thousand years, the size and vitality of cities, economies, and empires were heavily determined by infection. Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since... read more

Study finds genetic clues to pneumonia risk and COVID-19 disparities

Study finds genetic clues to pneumonia risk and COVID-19 disparities

Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. Their findings, published... read more