Tag: coronavirus
Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection
The current pandemic originated by SARS-CoV-2 causes an unprecedented health crisis. The medical world has found itself helpless in the face of this virus, having to deal with the absence of specific effective treatment.... read more
Is chloroquine or hydroxychloroquine useful in treating people with COVID-19, or in preventing infection in people who have been exposed to the virus?
COVID-19 is an infectious respiratory disease caused by a coronavirus called SARS-CoV-2. If the infection becomes severe, people may need intensive care and support in hospital, including mechanical ventilation. Drugs... read more
Barotrauma in Mechanically-ventilated Patients with COVID-2019
Within the limits of a survey, patients with COVID-19 might be at high risk for barotrauma during invasive (and allegedly lung-protective) mechanical ventilation. The response rate was 38/61 (62%). The incidence of... read more
Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients
Antibody responses are important in the control of viral respiratory infection in the human host. What is not clear for SARS-CoV-2 is how rapidly this response occurs, or when antibodies with protective capability evolve.... read more
RECOVERY trial shows tocilizumab reduces deaths in patients hospitalised with COVID-19
The NIHR-supported RECOVERY trial has shown that tocilizumab - an anti-inflammatory rheumatoid arthritis treatment - reduces the risk of death for hospitalised patients with severe COVID-19. Researchers also found that... read more
Surviving Sepsis Campaign Guidelines on the Management of Adults with COVID-19 in the ICU
The Surviving Sepsis Campaign Coronavirus Disease 2019 panel issued several recommendations to guide healthcare professionals caring for adults with critical or severe coronavirus disease 2019 in the ICU. Based on a living... read more
COVID-19 and VILI: Mechanical Power Measurement
The COVID-19 pandemic has increased the need for a bedside tool for lung mechanics assessment and ventilator-induced lung injury (VILI) monitoring. Mechanical power is a unifying concept including all the components which... read more
COVID-19 Awake Proning – All Hype?
In this prospective meta-analysis of observational studies of patients with acute hypoxemic respiratory failure due to COVID-19, APP did not result in lower intubation or mortality rates, despite reported improvements in... read more
Mediastinal lymphadenopathy may predict 30-day mortality in COVID-19 patients
Along with older age and consolidation pattern,enlarged mediastinal lymphadenopathy was found to be an independent predictor of 30-day mortality in patients with COVID-19. Although enlarged mediastinal lymphadenopathy... read more
COVID-19: Clinical manifestations of blood cell parameters and inflammatory factors
CRP and Lymphocyte count (LYM#) showed strong correlation with disease progression, suggesting that these parameters could be used to monitor changes in patient condition. 92 patients with confirmed COVID-19 at Jingzhou... read more
Covid PPE: How healthcare workers came to feel expendable
Over the course of the coronavirus pandemic, there have been hundreds of deaths among healthcare staff from Covid and many thousands off sick or self-isolating, but many hospital staff say they still don't feel properly protected... read more
Consequences of COVID-19 in discharged patients
At 6 months after acute infection, COVID-19 survivors were mainly troubled with fatigue or muscle weakness, sleep difficulties, and anxiety or depression. Patients who were more severely ill during their hospital stay... read more
FDA Limits Use of Convalescent Plasma as COVID-19 Treatment
The Food and Drug Administration (FDA) is scaling back its authorization of the use of convalescent blood-plasma for COVID-19 patients in an effort to guide physicians who have faced a confusing thicket of data about the... read more
Post-COVID Syndrome or Post-Sepsis Syndrome?
Since the initial outbreak of COVID-19, there have been reports of many people living with a new condition named post-COVID syndrome. These people are young and old, and they experience symptoms long after the infection has... read more
