Synthesis and Systematic Review of Reported Neonatal COVID-19 Infections

Synthesis and Systematic Review of Reported Neonatal COVID-19 Infections

A number of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections have been reported in neonates. Here, we aim to clarify the transmission route, clinical features and outcomes of these infections. We present... read more

The Effectiveness of 8 Nonpharmaceutical Interventions Against COVID-19 in 41 Countries

The Effectiveness of 8 Nonpharmaceutical Interventions Against COVID-19 in 41 Countries

Governments are attempting to control the COVID-19 pandemic with nonpharmaceutical interventions (NPIs). However, it is still largely unknown how effective different NPIs are at reducing transmission. Data-driven studies... read more

Outcomes of Neonates Born to Mothers With Severe COVID-19

Outcomes of Neonates Born to Mothers With Severe COVID-19

In this cohort study, no evidence of vertical transmission of SARS-CoV-2 was identified in the first 101 newborns born to mothers positive for or with suspected SARS-CoV-2 infections at a large medical center in an epicenter... read more

Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy

Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy

To the best of our knowledge, this is the first multicenter study that prospectively evaluated the benefits and the role of HFNO combined with awake prone positioning in the prevention of intubation in an adjusted large cohort... read more

VTE and COVID-19: Would you like to know more?

Who wouldn't want to know more about a disease that has killed >1 million people to date, worldwide. Who wouldn't want to know more about the thromboembolic risk associated with COVID-19 when we have been told that the VTE... read more

Factors Associated to ICU Mortality in Critically Ill Patients Infected with COVID-19 in Spain

Factors Associated to ICU Mortality in Critically Ill Patients Infected with COVID-19 in Spain

Older COVID-19 patients with higher APACHE II scores on admission, those who developed AKI grades II or III and/or septic shock during ICU stay had an increased risk-of-death. ICU mortality was 31%. A total of 663 patients... read more

Extracorporeal Cytokine Adsorption as an Alternative to Pharmacological Inhibition of IL-6 in COVID-19

Extracorporeal Cytokine Adsorption as an Alternative to Pharmacological Inhibition of IL-6 in COVID-19

With great interest we read the article by Convertino et al. discussing potential treatment targets for pharmacological immunomodulation in coronavirus disease 2019 (COVID-19) with acute respiratory distress syndrome (ARDS).... read more

Clinical Communication with Families in the Age of COVID-19

Clinical Communication with Families in the Age of COVID-19

The admission of a critically ill patient to an intensive care unit (ICU) is a distressing event for the patient, their family and friends, which has been amplified by the impact of the covid-19 pandemic. Many hospitals... read more

Endothelial Dysfunction Role During COVID-19

Endothelial Dysfunction Role During COVID-19

Emerging data suggest a crucial role of endothelial dysfunction during SARS-CoV-2 infection, as a direct target of the virus and inflammatory cytokines as well as the main actor in orchestrating a pro-inflammatory and pro-coagulant... read more

FDA Authorized First Point-of-Care Antibody Test for COVID-19

FDA Authorized First Point-of-Care Antibody Test for COVID-19

U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the first serology (antibody) point-of-care (POC) test for COVID-19. The Assure COVID-19 IgG/IgM Rapid Test Device was first authorized for... read more

Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19

Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19

This study found a higher rate of gastrointestinal complications, including mesenteric ischemia, in critically ill patients with COVID-19 compared with propensity score–matched patients without COVID-19, suggesting a distinct... read more

Pre-hospital Care & Interfacility Transport of 385 COVID-19 Emergency Patients

Pre-hospital Care & Interfacility Transport of 385 COVID-19 Emergency Patients

All participating air ambulance providers were prepared for COVID-19. Safe care and transport of suspected or confirmed COVID-19 patients is achievable. Most patients on primary missions were transported by ground. These... read more

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19

No benefit of hydroxychloroquine or chloroquine on the survival of COVID-19 patients found. For hydroxychloroquine, the confidence interval is compatible with increased mortality or negligibly reduced mortality. Findings... read more

Risk of Death More Than Doubled in People with Both Flu and COVID-19

Risk of Death More Than Doubled in People with Both Flu and COVID-19

People infected with both flu and SARS-CoV-2 are more than twice as likely to die as someone with the new coronavirus alone, emerging evidence from England has shown. An analysis by Public Health England (PHE) of cases... read more

Measuring COVID-19 Fatalities Among EMS Providers

Measuring COVID-19 Fatalities Among EMS Providers

The devastating effects of the COVID-19 pandemic resonate around the world. Escalating infection and death rates are reported daily. While emergency medical services clinicians have been operating at the far forward front... read more

Fibrin-derived Peptide as Salvage Treatment in Critically Ill Patients with COVID-19-associated ARDS

Fibrin-derived Peptide as Salvage Treatment in Critically Ill Patients with COVID-19-associated ARDS

After SARS-CoV-2 first occurred in China in December of 2019, it set out to become a global pandemic. Critically ill patients constitute about 2–9% of all infected patients and progress from pneumonia and hypoxemia to multi-organ... read more

COVID-19: Practical Strategies to Reduce Nosocomial Transmission

COVID-19: Practical Strategies to Reduce Nosocomial Transmission

The frontline healthcare workers (HCWs) are at risk for contracting the COVID-19 disease when caring for patients and providing aerosol-generating procedures. Until further high-quality studies generate robust evidence, defining... read more