The Case for Routine Screening for COVID-19 Before Surgery

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused more than 5 million cases of coronavirus disease (COVID-19) worldwide and 345,000 deaths as of 25 May 2020. Based on accumulating international experience... read more

The Case for Routine Screening for COVID-19 Before Surgery

Perhaps something isn’t always better than nothing

It is not unreasonable to say the COVID-19 pandemic caught most of us by surprise. We did not know how infectious the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) virus leading to COVID-19 disease was, nor... read more

Perhaps something isn’t always better than nothing

From despair to hope: advanced therapy gives a lifeline to the sickest COVID-19 patients

More than two months later, that piece of paper still lies on her coffee table with four letters on it: "E-C-M-O." Irena Veronese had never heard that acronym before, but when it was first mentioned to her, it meant moving... read more

From despair to hope: advanced therapy gives a lifeline to the sickest COVID-19 patients

Effect of Dexamethasone in Hospitalized Patients with COVID-19

Although the paper is not even officially published yet, everyone has already heard the results. We have our first treatment that appears to reduce mortality in COVID-19 patients. For a week or so, we only had press release,... read more

Effect of Dexamethasone in Hospitalized Patients with COVID-19

Procedural Sedation in the COVID-19 Era

Resuming procedural sedation services for elective procedures during the COVID-19 pandemic requires unique considerations to ensure safety for patients and providers. Guidelines for resuming these procedures, including timing,... read more

Procedural Sedation in the COVID-19 Era

What’s the Difference Between COVID-19 Tests?

The COVID-19 pandemic, tests, treatments, and outlook, continue to be front and center in the news, along with other urgent issues taking place across the country. Viral sepsis is the number one complication related to... read more

The Relevance of Thromboinflammation and Endothelial Dysfunction in COVID-19 Patients

The relevance of thromboinflammation and endothelial dysfunction in COVID-19 patients. Microvascular derangement is a key mechanism of multiple organ dysfunction and therapeutic strategies other than heparin, aimed at preserving... read more

The Relevance of Thromboinflammation and Endothelial Dysfunction in COVID-19 Patients

The COVID-19 Coronavirus is Changing

When a handful of doctors in northern Italy recently claimed that the virus that causes COVID-19 appears to be losing steam, that it no longer seems to be the same “biological bomb” it was when the pandemic first hit,... read more

The COVID-19 Coronavirus is Changing

Prevention, Detection and Management of VTE in COVID-19 Patients

Several studies have demonstrated coagulation changes in patients with COVID-19, especially in those with severe disease, and this is associated with a worse prognosis. Emerging data, alongside recent clinical experience,... read more

Prevention, Detection and Management of VTE in COVID-19 Patients

The use of continuous perineural catheters and other practices to optimize regional anesthesia in COVID-19 patients

As anesthesiologists, we are on the front line of the fight against coronavirus disease (COVID-19), whether in the intensive care unit, operating room, or elsewhere in the hospital. Given the highly contagious nature of the... read more

The use of continuous perineural catheters and other practices to optimize regional anesthesia in COVID-19 patients

The Impact on Pediatric Emergency Care during COVID-19

Although most children with COVID-19 are asymptomatic or present with mild disease, serious—but rare—complications are being seen in pediatric patients. This supplement describes the epidemiology, clinical features, and... read more

The Impact on Pediatric Emergency Care during COVID-19

Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients

Humanigen, the clinical stage biopharmaceutical company focused on preventing and treating cytokine storm, has reported positive data from the first clinical use of lenzilumab, its humaneered anti-human granulocyte macrophage-colony... read more

Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients

1m Physical Distancing Associated with a Large Reduction in COVID-19 Infection

The findings of this systematic review of 172 studies (44 comparative studies; n=25 697 patients) on COVID-19, SARS, and MERS provide the best available evidence that current policies of at least 1m (3 feet) physical distancing... read more

1m Physical Distancing Associated with a Large Reduction in COVID-19 Infection

Common Steroid Reduces Deaths Among Patients with Severe COVID-19

A cheap, readily available steroid drug reduced deaths by a third in patients hospitalized with Covid-19 in a large study, the first time a therapy has been shown to possibly improve the odds of survival with the condition... read more

Common Steroid Reduces Deaths Among Patients with Severe COVID-19

Identifying Airborne Transmission as the Dominant Route for the Spread of COVID-19

We have elucidated the transmission pathways of coronavirus disease 2019 (COVID-19) by analyzing the trend and mitigation measures in the three epicenters. Our results show that the airborne transmission route is highly... read more

Identifying Airborne Transmission as the Dominant Route for the Spread of COVID-19

Cardiopulmonary Resuscitation in the Emergency Department During COVID-19

Emergency medical services (EMS) is called for a 65-year-old man with a 1-week history of cough, fever, and mild shortness of breath now reporting chest pain. Vitals on scene were HR 110, BP 135/90, SpO2 88% on room air.... read more

Cardiopulmonary Resuscitation in the Emergency Department During COVID-19

AKI in Critically Ill Patients with COVID-19

Acute kidney injury (AKI) has been reported in up to 25% of critically-ill patients with SARS-CoV-2 infection, especially in those with underlying comorbidities. AKI is associated with high mortality rates in this setting,... read more

AKI in Critically Ill Patients with COVID-19

COVID-19 – Effective Triage During a Pandemic

The UK is likely on the brink of a major COVID-19 outbreak. About 6% to 10% of infected people are likely to be critically ill, most of whom will require ventilation support in an intensive care environment. Italy is already... read more

COVID-19 – Effective Triage During a Pandemic

Safe Airway Management for the Patient with COVID-19

In this presentation, Dr Ravi Bhagrath, Consultant Anaesthetist at Bart’s Health, London asks Dr Kariem El-Boghdadly, Consultant in Anaesthesia at Guy's and St Thomas' NHS Foundation Trust, London about the IntubateCOVID... read more

Safe Airway Management for the Patient with COVID-19