Tag: coronavirus
Supporting the Shielded – Results from a National Survey of Shielding Doctors
In spring, NHS staff responded to the looming COVID-19 pandemic with an impressive level of strategic planning. As operating theatres closed and ICU beds were created, anaesthetists and intensivists faced new challenges on... read more
COVID-19 and AKI
Recent reports from China, Italy, and the US indicate that there is a 25-37% incidence of AKI among critically ill COVID-19 patients (Singh 2020, Hirsch et al. 2020). In a study of 5,449 hospitalized COVID-19 patients, acute... read more
What is the Diagnostic Accuracy of Antibody Tests for the Detection of Infection with the COVID-19 Virus?
The sensitivity of antibody tests is too low in the first week since symptom onset to have a primary role for the diagnosis of COVID-19, but they may still have a role complementing other testing in individuals presenting... read more
The Case for Routine Screening for COVID-19 Before Surgery
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused more than 5 million cases of coronavirus disease (COVID-19) worldwide and 345,000 deaths as of 25 May 2020. Based on accumulating international experience... read more
Perhaps something isn’t always better than nothing
It is not unreasonable to say the COVID-19 pandemic caught most of us by surprise. We did not know how infectious the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) virus leading to COVID-19 disease was, nor... read more
From despair to hope: advanced therapy gives a lifeline to the sickest COVID-19 patients
More than two months later, that piece of paper still lies on her coffee table with four letters on it: "E-C-M-O." Irena Veronese had never heard that acronym before, but when it was first mentioned to her, it meant moving... read more
Effect of Dexamethasone in Hospitalized Patients with COVID-19
Although the paper is not even officially published yet, everyone has already heard the results. We have our first treatment that appears to reduce mortality in COVID-19 patients. For a week or so, we only had press release,... read more
Procedural Sedation in the COVID-19 Era
Resuming procedural sedation services for elective procedures during the COVID-19 pandemic requires unique considerations to ensure safety for patients and providers. Guidelines for resuming these procedures, including timing,... read more
What’s the Difference Between COVID-19 Tests?
The COVID-19 pandemic, tests, treatments, and outlook, continue to be front and center in the news, along with other urgent issues taking place across the country. Viral sepsis is the number one complication related to... read more
The Relevance of Thromboinflammation and Endothelial Dysfunction in COVID-19 Patients
The relevance of thromboinflammation and endothelial dysfunction in COVID-19 patients. Microvascular derangement is a key mechanism of multiple organ dysfunction and therapeutic strategies other than heparin, aimed at preserving... read more
The COVID-19 Coronavirus is Changing
When a handful of doctors in northern Italy recently claimed that the virus that causes COVID-19 appears to be losing steam, that it no longer seems to be the same “biological bomb” it was when the pandemic first hit,... read more
Prevention, Detection and Management of VTE in COVID-19 Patients
Several studies have demonstrated coagulation changes in patients with COVID-19, especially in those with severe disease, and this is associated with a worse prognosis. Emerging data, alongside recent clinical experience,... read more
The use of continuous perineural catheters and other practices to optimize regional anesthesia in COVID-19 patients
As anesthesiologists, we are on the front line of the fight against coronavirus disease (COVID-19), whether in the intensive care unit, operating room, or elsewhere in the hospital. Given the highly contagious nature of the... read more
The Impact on Pediatric Emergency Care during COVID-19
Although most children with COVID-19 are asymptomatic or present with mild disease, serious—but rare—complications are being seen in pediatric patients. This supplement describes the epidemiology, clinical features, and... read more
Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients
Humanigen, the clinical stage biopharmaceutical company focused on preventing and treating cytokine storm, has reported positive data from the first clinical use of lenzilumab, its humaneered anti-human granulocyte macrophage-colony... read more
1m Physical Distancing Associated with a Large Reduction in COVID-19 Infection
The findings of this systematic review of 172 studies (44 comparative studies; n=25 697 patients) on COVID-19, SARS, and MERS provide the best available evidence that current policies of at least 1m (3 feet) physical distancing... read more
Common Steroid Reduces Deaths Among Patients with Severe COVID-19
A cheap, readily available steroid drug reduced deaths by a third in patients hospitalized with Covid-19 in a large study, the first time a therapy has been shown to possibly improve the odds of survival with the condition... read more
