Tag: coronavirus
Ivermectin Not the Crisis It’s Claimed to Be
I can't remember any time when the U.S. Food and Drug Administration had to resort to the faux-folksy mode of expression to try to get its point across. We live in strange times. The FDA was responding, of course, to the... read more
SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus disease 2019 (COVID–19) pandemic, severely affecting public health and the global economy. Adaptive immunity plays a crucial role... read more
Year of the Nurse: A 2020 Covid-19 Pandemic Memoir
This book is for everyone, nurse or otherwise, who is furious about how 2020 went down and how 2021 is going. #1 Amazon Bestseller in Critical & Intensive Care Nursing #1 Amazon Bestseller in Mental Health Nursing #1... read more
How protein-based COVID vaccines could change the pandemic
Unlike the relatively new technologies that the mRNA and viral-vector COVID-19 shots are based on, protein vaccines have been used for decades to protect people from hepatitis, shingles and other viral infections. To... read more
Not all COVID waves look the same. Here’s a snapshot of the Delta surge
Waves of Covid can give you an awful sense of déjà vu. As "Hot Vax Summer" gave way early to Delta-anxious fall, you could be forgiven for feeling a familiar sense of dread, not so different from what you’d felt before... read more
The Unsung Heroes: Respiratory Therapists
Working day after day, year after year, in a busy high acuity ICU, we all have become a "second family." The public doesn't hear much about respiratory therapists, especially during this COVID nightmare. But they have... read more
Mechanically Ventilated COVID-19 Patients: Long-term Survival Study
The long-term survival of mechanically ventilated patients with severe COVID-19 reaches more than 50% and may help to provide individualized risk stratification and potential treatments. 868 patients were included (median... read more
Fluvoxamine COVID-19 Treatment: Positive Impact on Patient Survival
Fluvoxamine treatment in addition to the standard therapy in hospitalised ICU COVID-19 patients could have a positive impact on patient survival. Further studies on the effects of fluvoxamine in COVID-19 patients are urgently... read more
Cardiac Injury in COVID-19
Patients with coronavirus disease 2019 (COVID-19) can present with a large panel of cardiac manifestations, including myocardial infarction with (type 1) or without (type 2) obstructive coronary artery disease, arterial or... read more
HIV and COVID-19 Increased Risk of Severe Outcomes
People living with HIV with detectable HIV viraemia, chronic comorbidities, and some subpopulations could be at increased risk of severe outcomes from COVID-19. These groups should be prioritised in clinical management and... read more
COVID-19-related Death in Fully Vaccinated People in Scotland – Characteristics and Risk
Vaccines are highly effective in preventing COVID-19 hospitalisations and deaths. COVID-19-related deaths in fully vaccinated individuals have, however, been reported. To inform public health strategy and vaccination... read more
Early COVID-19 Treatment with SARS-CoV-2 Neutralizing Antibody Sotrovimab
Among high-risk patients with mild-to-moderate COVID-19, sotrovimab reduced the risk of disease progression. No safety signals were identified. The results of this interim analysis of COMET-ICE indicate that sotrovimab... read more
Differential Dynamics of Peripheral Immune Responses to Acute COVID-19 Infection in Older Adults
In this study, peripheral blood mononuclear cells from young and old patients with COVID-19 were examined phenotypically, transcriptionally and functionally to reveal age-, time- and severity-specific adaptations. Gene... read more
Risk of Death in Hospitalised COVID‐19 Patients Is Not Reduced by Azithromycin Treatment
The effect of antibiotics with potential antiviral and anti‐inflammatory properties are being investigated in clinical trials as treatment for COVID‐19. We are certain that risk of death in hospitalised COVID‐19... read more
