Experiences of ICU Nurses with an Innovative Digital Diary Intervention

Experiences of ICU Nurses with an Innovative Digital Diary Intervention

ICU nurses reported that the Post-ICU diary had added value for patients and their relatives. However, in the beginning they also experienced barriers such as lack of time, insufficient integration with their own work processes,... read more

Lessons Learned From the First 50 COVID-19 Critical Care Transfer Missions

Lessons Learned From the First 50 COVID-19 Critical Care Transfer Missions

Critically ill COVID-19 patients have highly complex medical needs during transport. Critical care transfer of COVID-19-positive patients by civilian HEMS services, including air transfer, can be achieved safely with specific... read more

The Value of Echocardiography Combined with Lung Ultrasound to Evaluate COVID-19 Pneumonia

The Value of Echocardiography Combined with Lung Ultrasound to Evaluate COVID-19 Pneumonia

In COVID-19 pneumonia patients, the pulmonary arterial pressure and LUS are positively correlated. For those who are unable to be transferred or relocated, the pulmonary arterial pressure may be measured to reflect the degree... read more

High-Dose Dexamethasone vs. Tocilizumab in COVID-19 Pneumonia

High-Dose Dexamethasone vs. Tocilizumab in COVID-19 Pneumonia

Our study findings discourage the use of high doses of dexamethasone in the management of moderate to severe COVID-19 ARDS. The routine use of such high doses to mitigate the inflammatory cytokine storm in these patients... read more

Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia

Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia

Vaccine-induced immune thrombotic thrombocytopenia is a serious complication of vaccination that is not feasible to anticipate or prevent. When the patient presents with sustained headache, neurologic symptoms/signs,... read more

New Resuscitation Guidance for Patients with COVID-19

New Resuscitation Guidance for Patients with COVID-19

In response to the COVID-19 pandemic, the American Heart Association and collaborating organizations, including the American Academy of Pediatrics, the American Association for Respiratory Care, the Society of Critical Care... read more

Inhaled Corticosteroid Use on COVID-19 Outcomes Among Hospitalized Adult Asthmatics

Inhaled Corticosteroid Use on COVID-19 Outcomes Among Hospitalized Adult Asthmatics

While our findings confirm trends observed by others with respect to risk factors among asthmatics with COVID-19, differences based on sex, ethnicity and ICS use in asthmatics were observed. Our finding that ICS use was associated... read more

The Role of Antiviral Treatment in the COVID-19 Pandemic

The Role of Antiviral Treatment in the COVID-19 Pandemic

US Food and Drug Administration (FDA) issued an emergency use authorisation for Pfizer's COVID-19 antiviral, Paxlovid few weeks ago. Trial results released by the manufacturer indicate that the drug cuts the risk of hospitalisation... read more

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

The significant mortality rate and prolonged ventilator days associated with invasive mechanical ventilation (IMV) in patients with severe COVID-19 have incited a debate surrounding the use of noninvasive respiratory support... read more

WHO Recommends Two New Drugs for COVID-19 Treatment

WHO Recommends Two New Drugs for COVID-19 Treatment

WHO has recommended two new drugs for COVID-19, providing yet more options for treating the disease. The extent to which these medicines will save lives depends on how widely available and affordable they will be. The... read more

Remdesivir Treatment for Hospitalized COVID-19 Patients in Canada

Remdesivir Treatment for Hospitalized COVID-19 Patients in Canada

Remdesivir, when compared with standard of care, has a modest but significant effect on outcomes important to patients and health systems, such as the need for mechanical ventilation. Across 52 Canadian hospitals, we randomized... read more

Study Supports Remdesivir Treatment for COVID-19 Patients on Low-Flow Oxygen or No Oxygen

Study Supports Remdesivir Treatment for COVID-19 Patients on Low-Flow Oxygen or No Oxygen

Remdesivir treatment increased the likelihood of clinical improvement in COVID-19 patients on low-flow oxygen or no oxygen, according to a new study by the Johns Hopkins University School of Medicine, the Johns Hopkins Bloomberg... read more

Efficacy of Inhaled Ciclesonide for Outpatient Treatment with Symptomatic COVID-19

Efficacy of Inhaled Ciclesonide for Outpatient Treatment with Symptomatic COVID-19

The results of this randomized clinical trial demonstrated that ciclesonide did not achieve the primary efficacy end point of reduced time to alleviation of all COVID-19–related symptoms. A total of 413 participants... read more

1-year Mortality After COVID-19 ICU Admission

1-year Mortality After COVID-19 ICU Admission

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes severe disease in some patients. Patients can experience severe disabilities after intensive care unit (ICU) admission due to coronavirus disease... read more