Awake Prone Positioning for COVID-19 Hypoxemic Respiratory Failure

Infection with SARS-CoV-2 can result in Coronavirus Disease–19 (COVID-19). While the majority of patients are asymptomatic or have mild disease, approximately 14% develop more severe disease including hypoxemic respiratory... read more

Evaluation of SARS-CoV-2 Serology Assays Reveals a Range of Test Performance

Appropriate use and interpretation of serological tests for assessments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, infection and potential immunity require accurate data on assay performance.... read more

When Should I Worry About a PE in a Patient with COVID-19

PE diagnosis in COVID-19 patients is challenging. Many of the features of PE, such as shortness of breath and hypoxemia, are very common in patients with COVID-19, even in the absence of PE. Further, the diagnostic tests... read more

Respiratory Support in Patients with COVID-19

Non-invasive respiratory support could be useful in treating COVID-19-related acute respiratory failure (ARF). A rational use of different techniques (oxygen therapy, CPAP, NIV or HFOT) by a trained pulmonologist could allow... read more

Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children

Acute myocarditis with intense systemic inflammation and atypical Kawasaki disease is an emerging severe pediatric disease following SARS-CoV-2 infection. Early recognition of this disease is needed and referral to an expert... read more

Variation in Hospital Visitor & ICU Communication Policies Due to COVID-19

A new study documents how 49 of those hospitals reacted, and how those efforts varied. It finds that virtually all hospitals put in place a "no visitors" blanket policy. But 59% of hospitals did allow some exceptions to this... read more

How AI is Reshaping Healthcare During COVID-19

As the healthcare and pharmaceutical industries rush to tackle a wide range of COVID-19 challenges, from developing treatments and sourcing medical supplies to mitigating outbreaks and racing towards a vaccine, the use of... read more

Plasma Exchange in Critically Ill COVID-19 Patients

The spectrum of coronavirus disease 2019 (COVID-19) ranges from asymptomatic infection to respiratory failure and death of patients. Severely affected patients may develop a cytokine storm-like clinical syndrome with multi-organ... read more

Prone Positioning in Non-intubated Patients with COVID-19

As the COVID-19 pandemic has put severe stress and strain on the capacity of hospitals around the world, concerted efforts have been made to evaluate therapeutics aimed at preventing the need for mechanical ventilation. The... read more

ICU Capacity is More About the Clinicians Than The Number of Beds

Each time communities experience surges of COVID-19, concerns arise over the availability of hospital and intensive care unit beds in affected regions. To monitor ICU capacity, several states have begun to track and publicly... read more

Impact of Cardiovascular Risk Profile on COVID-19 Outcome

This study investigates the extent of cardiac comorbidities and complications among hospitalized patients with COVID-19. Cardiovascular complications are frequent among COVID-19 patients, and might contribute to adverse... read more

Post-Hospital VTE in Patients with COVID-19

The authors concluded that the rate of post-hospital venous thromboembolism (VTE) among patients with COVID-19 is low and that routine post-hospital prophylaxis is not necessary. Of the 1,877 hospital admissions with COVID-19... read more

Philips Launches COVID-19 Rapid Equipment Deployment Kit for ICUs

Royal Philips introduced its Rapid Equipment Deployment Kit for ICU ramp-ups, allowing doctors, nurses, technicians and hospital staff to quickly support critical care patient monitoring capabilities during the COVID-19 pandemic.... read more

Laboratory Features of Severe vs. Non-severe COVID-19 Patients in Asian Populations

This meta-analysis provides evidence for the differentiation of severe cases of COVID-19 based on laboratory test results at the time of ICU admission. Future well-methodologically designed studies from other populations... read more

Fit-testing of N95/P2-masks to Protect Healthcare Workers

In the context of COVID-19, well fitted respirators e.g. N95/P2-masks are recommended as part of personal protective equipment when performing aerosol generating procedures. Fit-checking is recommended prior to donning... read more

ICU Trends for Patients with COVID-19 in England, Wales and Northern Ireland

Observed trends suggest opposing effects of ICU strain and clinical learning. Further investigation is needed to identify modifiable system factors that could alleviate strain in future epidemics and changes in clinical practice... read more

Pulmonary Embolism in COVID-19 Patients in France

Pulmonary embolism (PE) in the context of coronavirus disease 2019 (COVID-19) appears to be driven largely by inflammation and coagulopathy rather than by traditional risk factors for thromboembolism. Study results suggest... read more

Pediatric Critical Care and COVID-19

We provide early clinical and laboratory data about critical pediatric COVID-19, which suggest a variable disease but generally good outcomes compared with adults. Targets for research include the course of organ failure... read more

Non-Invasive Cardiac Imaging for LVAD and OHT During COVID-19

Considerations for cardiac imaging in the COVID-19 era include thoughtful patient and study selection with a goal to limit the overall number of tests. General recommendations are as follows: Defer routine or low-risk... read more

ICU Doctor Creates App to Help Patients on Ventilators Communicate Faster

ICU Doctor Chandar Abboy and his partner came up with a way to give a voice to the voiceless. The app called “Yo Doc” allows patients on ventilators to better communicate their needs and feelings. Dr. Abboy says this... read more

The Use of ECMO in Patients with Cardiopulmonary Failure Due to COVID-19

COVID-19 related cardiopulmonary failure such as ARDS and cardiogenic shock or massive pulmonary embolism can be successfully supported with ECMO. Judicious patient selection is important to enable maximal benefit and optimized... read more

Serum Levels of Receptor-interacting Protein Kinase-3 in Patients with COVID-19

Patients with coronavirus disease 2019 (COVID-19) can develop acute respiratory distress syndrome (ARDS), which has been linked to poor prognosis and is a major contributor to patient death. A better understanding of the... read more