Tag: COVID-19
The COVID-19 Coronavirus is Changing
When a handful of doctors in northern Italy recently claimed that the virus that causes COVID-19 appears to be losing steam, that it no longer seems to be the same “biological bomb” it was when the pandemic first hit,... read more
Prevention, Detection and Management of VTE in COVID-19 Patients
Several studies have demonstrated coagulation changes in patients with COVID-19, especially in those with severe disease, and this is associated with a worse prognosis. Emerging data, alongside recent clinical experience,... read more
The use of continuous perineural catheters and other practices to optimize regional anesthesia in COVID-19 patients
As anesthesiologists, we are on the front line of the fight against coronavirus disease (COVID-19), whether in the intensive care unit, operating room, or elsewhere in the hospital. Given the highly contagious nature of the... read more
The Impact on Pediatric Emergency Care during COVID-19
Although most children with COVID-19 are asymptomatic or present with mild disease, serious—but rare—complications are being seen in pediatric patients. This supplement describes the epidemiology, clinical features, and... read more
Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients
Humanigen, the clinical stage biopharmaceutical company focused on preventing and treating cytokine storm, has reported positive data from the first clinical use of lenzilumab, its humaneered anti-human granulocyte macrophage-colony... read more
1m Physical Distancing Associated with a Large Reduction in COVID-19 Infection
The findings of this systematic review of 172 studies (44 comparative studies; n=25 697 patients) on COVID-19, SARS, and MERS provide the best available evidence that current policies of at least 1m (3 feet) physical distancing... read more
Common Steroid Reduces Deaths Among Patients with Severe COVID-19
A cheap, readily available steroid drug reduced deaths by a third in patients hospitalized with Covid-19 in a large study, the first time a therapy has been shown to possibly improve the odds of survival with the condition... read more
Identifying Airborne Transmission as the Dominant Route for the Spread of COVID-19
We have elucidated the transmission pathways of coronavirus disease 2019 (COVID-19) by analyzing the trend and mitigation measures in the three epicenters. Our results show that the airborne transmission route is highly... read more
Cardiopulmonary Resuscitation in the Emergency Department During COVID-19
Emergency medical services (EMS) is called for a 65-year-old man with a 1-week history of cough, fever, and mild shortness of breath now reporting chest pain. Vitals on scene were HR 110, BP 135/90, SpO2 88% on room air.... read more
AKI in Critically Ill Patients with COVID-19
Acute kidney injury (AKI) has been reported in up to 25% of critically-ill patients with SARS-CoV-2 infection, especially in those with underlying comorbidities. AKI is associated with high mortality rates in this setting,... read more
COVID-19 – Effective Triage During a Pandemic
The UK is likely on the brink of a major COVID-19 outbreak. About 6% to 10% of infected people are likely to be critically ill, most of whom will require ventilation support in an intensive care environment. Italy is already... read more
Safe Airway Management for the Patient with COVID-19
In this presentation, Dr Ravi Bhagrath, Consultant Anaesthetist at Bart’s Health, London asks Dr Kariem El-Boghdadly, Consultant in Anaesthesia at Guy's and St Thomas' NHS Foundation Trust, London about the IntubateCOVID... read more
Innovative Approaches to Patient Rehabilitation Maximize COVID-19 Recovery
People hospitalized with COVID-19 can experience debilitating physical changes — extreme fatigue, difficulty breathing and muscle weakness, says April Pruski, M.D., a Johns Hopkins physiatrist (a medical doctor who specializes... read more
Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepam
This case demonstrates the importance of rapid recognition and treatment of hydroxychloroquine poisoning. We anticipate that clinicians may be asked to recognize and manage this toxidrome in increasing frequency as attention... read more
Preparing for COVID-19 Related Drug Shortages
The COVID-19 pandemic has dramatically impacted all aspects of healthcare delivery. There is widespread concern that increased clinical demands due to the virus will outstrip available resources. Much attention has focused... read more
Ethnicity and Outcomes in Patients Hospitalised with COVID-19
Preliminary studies suggest that people from Black, Asian and Minority Ethnic (BAME) backgrounds experience higher mortality from COVID-19 but the underlying reasons remain unclear. Prospective analysis of registry data... read more
How and When to End the COVID-19 Lockdown
Countries around the world are in a state of lockdown to help limit the spread of SARS-CoV-2. However, as the number of new daily confirmed cases begins to decrease, governments must decide how to release their populations... read more
Ventilator Management in the Age of COVID-19
In the age of coronavirus disease-19 (COVID-19), conservation of personal protective equipment (PPE) represents an urgent public health priority. Vargas et al. describe a logistic project and organizational plan to prevent... read more
Spotting the Clotting: Hypercoagulopathy in COVID-19
Evolving experience with TEG, clotting parameters, treatment considerations, and ongoing data gathering will help us better understand if antiplatelet therapy with aspirin or clopidogrel or anticoagulant treatment with traditional... read more
Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2
In this case series of hospitalized children who met criteria for PIMS-TS, there was a wide spectrum of presenting signs and symptoms and disease severity, ranging from fever and inflammation to myocardial injury, shock,... read more
Managing Theatre Processes for Planned Surgery Between COVID-19 Surges
As we emerge from the first pandemic surge, there is a widespread desire to restart planned surgery using patient pathways that seek to minimise COVID-19 risk to patients and healthcare workers (HCWs). Some hospitals... read more
ACEI/ARB Use and Testing Positive for COVID-19
This retrospective cohort study reports that taking either an angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) was not associated with an increase in the likelihood of testing positive... read more
