Postextubation Complications vs. Positive-Pressure Suctioning Techniques

Postextubation Complications vs. Positive-Pressure Suctioning Techniques

Currently available studies that compared post-extubation complications in subjects managed with the positive-pressure and suctioning techniques were summarized. Further high-quality studies with a robust study design and... read more

Regular Old Pneumonia Treatment Just Got Better

Regular Old Pneumonia Treatment Just Got Better

In 2020, COVID-19 pneumonia became so common that "old-fashioned" bacterial pneumonia suddenly seemed rare. They look very different on x-ray. See if you can spot the differences. A new study from France tipped the scales... read more

COVID-19 in Solid Organ Transplant Recipients

COVID-19 in Solid Organ Transplant Recipients

Solid Organ Transplant (SOT) recipients are at high risk of severe coronavirus disease-2019. Prior to the availability of vaccination, passive immunotherapies and effective antiviral therapeutics, the outcomes of COVID-19... read more

Clinical Cases in Critical Care

Clinical Cases in Critical Care

In Clinical Cases in Critical Care, the authors explore core clinical topics and basic sciences in a practical and realistic way, and include comprehensive discussions focusing on critically unwell patients with a variety... read more

ICU Precision Diagnosis with Metagenomic Sequencing

ICU Precision Diagnosis with Metagenomic Sequencing

Despite promising results, metagenomics remains underutilized in the ICU. Several factors still limit its inclusion in routine critical care, including the lack of definitive clinical trials testing its utility, few laboratories... read more

Practical Trends in Anesthesia and Intensive Care 2020-2021

Practical Trends in Anesthesia and Intensive Care 2020-2021

This book offers an essential guide to managing the most-debated hot topics of practical interest in anesthesia and intensive care. Part I reviews the state of the art in issues concerning both intensive care medicine... read more

Polymorphism in Interferon Alpha/Beta Receptor Contributes to Glucocorticoid Response and Outcome of ARDS and COVID-19

Polymorphism in Interferon Alpha/Beta Receptor Contributes to Glucocorticoid Response and Outcome of ARDS and COVID-19

The distribution of this SNP within clinical study arms may explain the contradictory results of multiple ARDS studies and outcomes in COVID-19 concerning type I IFN signaling and glucocorticoids. We found a novel disease... read more

COVID-19 Pandemic Effect on the Incidence and Survival Outcomes of EMS-witnessed OHCA

COVID-19 Pandemic Effect on the Incidence and Survival Outcomes of EMS-witnessed OHCA

While other international studies have observed higher incidence and reduced survival in non-EMS-witnessed out-of-hospital cardiac arrest (OHCA) during the COVID-19 pandemic, this study did not identify any significant impacts... read more

Targeted Immunomodulation: A Primer for Intensivists

Targeted Immunomodulation: A Primer for Intensivists

Targeted immunomodulation is a topic that gained wide interest from translational researchers in the past decades, yet immunomodulatory drugs were not frequently administered to intensive care patients. The coronavirus... read more

Continuous Positive Airway Pressure Usage During COVID-19

Continuous Positive Airway Pressure Usage During COVID-19

We confirm that use of early continuous positive airway pressure (CPAP) with high-flow output combined with an "ad hoc" algorithm to inform the decision to intubate is a valid and safe strategy for respiratory support in... read more

COVID-19 Treatment Guidelines New Version Published

COVID-19 Treatment Guidelines New Version Published

The COVID-19 Treatment Guidelines Panel (the Panel) is pleased to announce the publication of an updated version of the Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. In the United States, the prevalence of... read more

Loved Ones Are Not “Visitors” in a Patient’s Life

Loved Ones Are Not “Visitors” in a Patient’s Life

Hospitals are institutions whose primary task is to treat patients. Family-centered care, which considers loved ones as equal partners in patient care, has been gaining recognition in the adult care setting. Our aim was... read more

Rising Mortality in COVID-19 Patients Supported With ECMO

Rising Mortality in COVID-19 Patients Supported With ECMO

We aimed to describe practice patterns and outcomes in patients with extracorporeal membrane oxygenation (ECMO) support throughout the coronavirus 2019 (COVID-19) pandemic, with the hypothesis that mortality would improve... read more

Increased Risk of Hospitalization in Celiac Disease with COVID-19 Infection Is Mitigated by Vaccination

Increased Risk of Hospitalization in Celiac Disease with COVID-19 Infection Is Mitigated by Vaccination

Celiac disease (CD) patients with COVID-19 have a higher risk of hospitalization compared with non-CD referents. This risk is mitigated by vaccination in CD patients as it is in non-CD referents. ICU requirement occurred... read more