Resetting the Circadian Clock Might Boost Metabolic Health

This Medical News feature discusses the role of circadian clock in regulating metabolism. Over the past 20 years, scientists have assembled a clearer picture of the circadian clocks that keep human physiology tuned to the... read more

Resetting the Circadian Clock Might Boost Metabolic Health

Liberal Glycemic Control in Critically Ill Patients With Type 2 Diabetes

Ludwig Lin, MD, speaks with Palash Kar, MBBS, about the article, "Liberal Glycemic Control in Critically Ill Patients With Type 2 Diabetes: An Exploratory Study," published in Critical Care Medicine. In this article, Dr.... read more

IV Fluids and Solutions Quick Reference Guide Cheat Sheet

Intravenous solutions are used in fluid replacement therapy by changing the composition of the serum by adding fluids and electrolytes. Quick reference guide on the different intravenous solutions.... read more

IV Fluids and Solutions Quick Reference Guide Cheat Sheet

Hospitalist Tackles Chronic Disease With Food Pharmacies

Before January 2017, Rita Nguyen, MD, was "pretty much like any other academic hospitalist," she says. In the hospital, she could provide excellent care to patients, but once they were discharged, many didn't have the necessary... read more

Hospitalist Tackles Chronic Disease With Food Pharmacies

We Need to Talk About Trauma

One of the most haunting images from my time as a junior doctor working in Hackney in the mid-1990s was in an A&E (emergency) department while we tried to resuscitate a man in his 40s. In the corner of the room stood two... read more

Diabetes Risks and Outcomes in COPD Patients

The relationship between chronic obstructive pulmonary disease (COPD) and diabetes remains incompletely understood. This study evaluated diabetes risk and post-diabetes outcomes in COPD patients with and without exacerbations.... read more

Diabetes Risks and Outcomes in COPD Patients

A simple algorithm for the identification of clinical COPD phenotypes

This study aimed to identify simple rules for allocating chronic obstructive pulmonary disease (COPD) patients to clinical phenotypes identified by cluster analyses.Data from 2409 COPD patients of French/Belgian COPD cohorts... read more

A simple algorithm for the identification of clinical COPD phenotypes

Risk of AKI After Intravenous Contrast Media Administration

In the largest well-controlled study of acute kidney injury (AKI) following contrast administration in the ED to date, intravenous contrast was not associated with an increased frequency of acute kidney injury. Rates of acute... read more

Risk of AKI After Intravenous Contrast Media Administration

A comparison of two insulin infusion protocols in the ICU by continuous glucose monitoring

The Yale protocol provided better average glycemia, more time spent in normoglycemia, less time in hypoglycemia, and less glycemic variability than the Leuven protocol, but was not independently associated with strict glycemic... read more

A comparison of two insulin infusion protocols in the ICU by continuous glucose monitoring

Performance of a Modern Glucose Meter in ICU

Performance of a Modern Glucose Meter in ICU and General Hospital Inpatients: 3 Years of Real-World Paired Meter and Central Laboratory Results. Due to accuracy concerns, the Food and Drug Administration issued guidance to... read more

Performance of a Modern Glucose Meter in ICU

Airway Management of The Morbidly Obese Patient

Obesity is a major health care dilemma. All aspects of medical care, including anesthesia, are affected by it. All physiologic systems are altered by obesity, which imparts a higher risk for complications in the perioperative... read more

Airway Management of The Morbidly Obese Patient

Hyperglycaemia in Critically Ill Patients

There is an ongoing debate regarding the efficacy of glycaemic control in critically ill patients. Here we briefly highlight the key function of elevated glucose in critically ill patients, namely, to enable elevation of... read more

Hyperglycaemia in Critically Ill Patients

Link Between Diabetes and Hospital Readmission Rates

Patients with diabetes have higher rates of hospital readmission compared with patients without diabetes, according to a pilot study published in Clinical Diabetes and Endocrinology. In the first study, the readmission rate... read more

Link Between Diabetes and Hospital Readmission Rates

Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old Type 2 Diabetic Patients

Type 2 diabetes (T2D) in elderly patients is associated with accelerated loss of skeletal muscle mass and strength. However, there are few meta-analysis reviews which investigate the effects of resistance training (RT) on... read more

Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old Type 2 Diabetic Patients

Genomics, Health Disparities, and Missed Opportunities for the Nation’s Research Agenda

The completion of the Human Genome Project occurred at a time of increasing public attention to health disparities. In 2004, Sankar and colleagues1 suggested that this coincidental timing resulted in an inappropriate emphasis... read more

Genomics, Health Disparities, and Missed Opportunities for the Nation’s Research Agenda

Care that Matters: Quality Measurement and Health Care

Barry Saver and colleagues caution against the use of process and performance metrics as health care quality measures in the United States. There is limited evidence that many "quality" measures - including those... read more

Care that Matters: Quality Measurement and Health Care

Portable Imaging Device Assesses Tissue Oxygenation

A handheld, battery operated diagnostic imaging device measures oxygen saturation (O2Sat) and other measures in superficial tissues for patients with potential circulatory compromise. The HyperView is intended for use by... read more

Portable Imaging Device Assesses Tissue Oxygenation

Better glycemic control with continuous glucose monitoring

This randomized clinical trial compares the effects of continuous glucose monitoring vs conventional treatment for glycemic control in adult patients with type 1 diabetes treated with multiple daily insulin injections.... read more

Better glycemic control with continuous glucose monitoring

COPD Patients in US Often Skip Medications

People with chronic obstructive pulmonary disease (COPD) often have other chronic conditions, like heart disease, and those who are poor about keeping up with treatments for these comorbidites are also less likely to adhere... read more

COPD Patients in US Often Skip Medications

Metformin Associated with Reduced Mortality in CKD, CHF, and CLD

Metformin is currently the suggested initial treatment for type 2 diabetes mellitus in the United States. In the past, the U.S. Food and Drug Administration (FDA) did not recommend metformin for patients with chronic kidney... read more

Metformin Associated with Reduced Mortality in CKD, CHF, and CLD

Serum biomarker associated with metformin dosing or use

The growth differentiation factor 15 (GDF15) is a novel biomarker for the use and dosing of metformin, according to a study published online Dec. 14 in Diabetes Care. 237 serum biomarkers from participants in the Outcome... read more

Serum biomarker associated with metformin dosing or use