The Hidden Value of MRI: Modifying Treatment Decisions in C-spine Injuries

This study provides a critical evaluation of the implications of additional magnetic resonance imaging (MRI) use in the diagnosis of c-spine injuries. We have demonstrated that an adjunctive MRI extends patients' ED stays,... read more

Genetic Testing in Early-onset Atrial Fibrillation

Atrial fibrillation (AF) is a globally prevalent cardiac arrhythmia with significant genetic underpinnings, as highlighted by recent large-scale genetic studies. A prominent clinical and genetic overlap exists between... read more

Prevalence and Survival of Prolonged VV ECMO for ARDS

The understanding of prolonged venovenous extracorporeal membrane oxygenation (VV ECMO) in the setting of acute respiratory distress syndrome (ARDS) is evolving and durations of support once considered extreme are now commonplace.... read more

The Existence of Adrenal Insufficiency in COVID-19 Patients with Pneumonia

Patients with a history of COVID-19 pneumonia who present with clinical symptoms such as shock, nausea, vomiting, and fatigue should have hypocortisolism included in the differential diagnosis. These patients should also... read more

Lung Ultrasound for Diagnosis and Management of ARDS

Lung ultrasonography (LUS) is essential for diagnosing and managing adult respiratory distress syndrome (ARDS) due to its bedside accessibility and availability across different resource settings. It aids in diagnosis and... read more

Lung Ultrasound for Diagnosis and Management of ARDS

Diagnosing Sepsis: Where We’re At And Where We’re Going

Diagnosing sepsis remains problematic. Pathogen identification is frequently lacking and the dysregulated host response is non-specific. Blood cultures often take days to deliver a result and, even then, approximately 90%... read more

Diagnosing Sepsis: Where We’re At And Where We’re Going

Traumatic Major Hemorrhage in a Tertiary Trauma Center

Major traumatic hemorrhage is potentially preventable with rapid hemorrhage control and improved resuscitation techniques. The time from injury to hospital, resuscitation, diagnosis, and definitive bleeding control should... read more

Traumatic Major Hemorrhage in a Tertiary Trauma Center

Ineffective Airway Clearance Nursing Diagnosis & Care Plans

Ineffective airway clearance is the inability to clear secretions or obstructions from the respiratory tract. This can be detrimental to breathing and create complications. Secretions can be problematic as a result of... read more

Ineffective Airway Clearance Nursing Diagnosis & Care Plans

Oxygenation Improvement in Hyperinflammatory Ovine ARDS Treated with Methylprednisolone

Early and persistent improvement in oxygenation was seen only in hyperinflammatory ovine ARDS treated with methylprednisolone, while hemodynamic situation and survival was improved in both injury models and corticosteroid... read more

Oxygenation Improvement in Hyperinflammatory Ovine ARDS Treated with Methylprednisolone

A Global Perspective on AKI After Major Surgery

Acute kidney injury (AKI) is an abrupt decline in kidney function occurring within hours or days. In patients having surgery, postoperative AKI is a major complication associated with adverse outcomes including mortality.... read more

A Global Perspective on AKI After Major Surgery

COVID-19 Severity and 2-year Prevalence of Physical Symptoms

Although the persistence of physical symptoms after SARS-CoV-2 infection is a major public health concern, evidence from large observational studies beyond one year post diagnosis remain scarce. We aimed to assess the prevalence... read more

COVID-19 Severity and 2-year Prevalence of Physical Symptoms

Simple Blood Test Indicating Sepsis Relapse

Sepsis is often not adequately diagnosed at the early stage when it could still be potentially avoidable. In this report, we describe the dramatic hematological changes found in the blood of a sepsis survivor just after discharge... read more

Simple Blood Test Indicating Sepsis Relapse

What to Know About Merkel Cell Carcinoma, the Rare Cancer that Killed Jimmy Buffett

"Margaritaville" singer Jimmy Buffett died of Merkel cell carcinoma, a rare but aggressive form of skin cancer, according to a tribute posted on his official websiteopens in a new tab or window. The 76-year-old music icon... read more

What to Know About Merkel Cell Carcinoma, the Rare Cancer that Killed Jimmy Buffett

Neonatology Questions and Controversies: Neonatal Hemodynamics

Dr. Richard Polin's Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment... read more

Neonatology Questions and Controversies: Neonatal Hemodynamics

A Promising Biomarker for Early Detection of Acute Coronary Syndrome (ACS)

As found in our study, among the biomarkers used, the diagnostic accuracy of IMA was the highest and better than that of cardiac troponin I and CK-MB. Although ECG is the preferred diagnostic tool for diagnosing ACS (STEMI,... read more

A Promising Biomarker for Early Detection of Acute Coronary Syndrome (ACS)

High-Sensitivity Troponin T in a Secondary Care Setting

High-sensitivity troponin (hs-cTn) assays play a crucial role in the early detection and management of patients with suspected acute coronary syndrome (ACS). This study supports evidence that serial troponin measurements... read more

High-Sensitivity Troponin T in a Secondary Care Setting

Estimating Seroprevalence of COVID-19 Infection After Omicron Outbreak

This study aimed to investigate the seroprevalence of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antibodies among individuals aged 18 years and older. Population-based study was conducted within the Arizona... read more

Estimating Seroprevalence of COVID-19 Infection After Omicron Outbreak

Sepsis Prediction Model for Determining Sepsis vs. SIRS, qSOFA, and SOFA

In this cohort study of 60,507 hospital admissions, we found that although the SPM marginally outperformed existing prediction scores in balanced accuracy for classification of sepsis, it suffers from poor timeliness, limiting... read more

Sepsis Prediction Model for Determining Sepsis vs. SIRS, qSOFA, and SOFA

A Case of Chronic Mesenteric Ischemia Due to Celiac and Mesenteric Artery Thrombosis

Chronic mesenteric ischemia (CMI) is uncommon and accounts for approximately 5% of cases. CMI presents with non-specific symptoms, making it difficult to diagnose, and requires complex management involving interprofessional... read more

A Case of Chronic Mesenteric Ischemia Due to Celiac and Mesenteric Artery Thrombosis

AKI Defined by Fluid-Corrected Creatinine in Premature Neonates

In this secondary analysis of the multicenter PENUT trial, we describe fluid-corrected acute kidney injury (AKI) and evaluate associations with short-term and long-term outcomes in premature neonates with fluid-corrected... read more

AKI Defined by Fluid-Corrected Creatinine in Premature Neonates

The Contribution of Procalcitonin, C-Reactive Protein and Interleukin-6 in the Diagnosis and Prognosis of Surgical Sepsis

The mortality rate was quite high in our study, consistent with the elevated serum biomarker concentrations, which were higher in non-survivors compared with survivors. C-reactive protein (CRP) and IL-6 were the most effective... read more

The Contribution of Procalcitonin, C-Reactive Protein and Interleukin-6 in the Diagnosis and Prognosis of Surgical Sepsis

Ground-breaking New AI Technology for Severe Sepsis Rapid Identification

ASEP Medical Holdings Inc. announced the ground-breaking use of artificial intelligence (AI) to rapidly identify infections at increased risk of severe sepsis. The method was developed by the Hancock Lab, under the guidance... read more

Ground-breaking New AI Technology for Severe Sepsis Rapid Identification