Increase in PI during PLR detects a positive response of the PLR test

Increase in PI during PLR detects a positive response of the PLR test

An increase in perfusion index (PI) during passive leg raising (PLR) by 9% accurately detects a positive response of the PLR test. Three patients were excluded because the plethysmography signal was absent and 3 other... read more

Left Septal Fascicular Block

Left Septal Fascicular Block

This book provides clinical and electrovectorcardiographic evidence of the existence of left septal fascicular blocks and demonstrates the clinical importance of these blocks in the clinical scenario of acute coronary syndrome.... read more

Could a Glass of Wine Diagnose Long COVID?

Could a Glass of Wine Diagnose Long COVID?

Acute COVID-19 infection ranges from no symptoms (asymptomatic) to life-threatening. What about long COVID (the symptoms occurring more than three weeks after infection, also known as post-acute COVID syndrome)? Could... read more

FDA Authorizes Adaptive Biotechnologies T-Detect COVID Test

FDA Authorizes Adaptive Biotechnologies T-Detect COVID Test

U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the T-Detect COVID Test developed by Adaptive Biotechnologies. The T-Detect COVID Test is a next generation sequencing based (NGS) test... read more

Antiviral Drugs in Hospitalised COVID-19 Patients

Antiviral Drugs in Hospitalised COVID-19 Patients

These remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19, as indicated by overall mortality, initiation of ventilation, and duration of hospital... read more

Point-of-Care Ultrasound (POCUS) and COVID-19

Point-of-Care Ultrasound (POCUS) and COVID-19

COVID-19 is a disease caused by infection with SARS-CoV-2, a virus that affects multiple organ systems with numerous disease manifestations. COVID-19 has a specific tropism for the lower respiratory tract, and the most common... read more

Temporal Changes in the Epidemiology, Management, and Outcome from ARDS

Temporal Changes in the Epidemiology, Management, and Outcome from ARDS

The frequency of and outcome from ARDS remained relatively stable between 2002 and 2012. Plateau pressure > 29 cmH2O and driving pressure > 14 cmH2O on the first day of mechanical ventilation but not tidal volume > 8... read more

Insight into ECMO, mortality and ARDS

Insight into ECMO, mortality and ARDS

ARDS is a severe disease with a high mortality rate despite ECLS therapy. Although endpoints and timing of the evaluations differed from those of the CESAR and EOLIA studies and the Extracorporeal Life Support Organization... read more

How can artificial intelligence transform pneumonia diagnosis?

How can artificial intelligence transform pneumonia diagnosis?

Hot on the heels of FDA approval for its AI-guided cardiac ultrasound software, Caption has received a $4.95m grant from the Gates Foundation to create a version that could speed up pneumonia diagnosis, the leading killer... read more

Subtle Presentations of Shock in the ED Setting

Subtle Presentations of Shock in the ED Setting

The patient was a 2-year-old female with a history of allergy to peanuts who was brought to the emergency department by her mother because of a complaint of allergic reaction. Twenty minutes prior to arrival, the patient... read more

Colchicine, the only effective oral medication for treating non-hospitalized COVID-19 patients

Colchicine, the only effective oral medication for treating non-hospitalized COVID-19 patients

The Montreal Heart Institute announced COLCORONA clinical trial has provided clinically persuasive results of colchicine's efficacy to treat COVID-19. The study results show that colchicine reduces the risk of death or... read more

Use of a Machine Learning Model to Predict Iatrogenic Hypoglycemia

Use of a Machine Learning Model to Predict Iatrogenic Hypoglycemia

These findings suggest that iatrogenic hypoglycemia can be predicted in a short-term prediction horizon after each BG measurement during hospitalization. Further studies are needed to translate this model into a real-time... read more

Management of late onset urea cycle disorders-a remaining challenge for the intensivist?

Management of late onset urea cycle disorders-a remaining challenge for the intensivist?

Awareness of urea cycle disorders in adults intensive care units can optimize early management and accordingly dramatically improve prognosis. By preventing hyperammonemia to induce brain edema and herniation leading to death. Hyperammonemia... read more

Ivermectin for COVID-19, Breakthrough Treatment or Hydroxychloroquine Redux?

Ivermectin for COVID-19, Breakthrough Treatment or Hydroxychloroquine Redux?

It’s an indisputable fact that we need better treatments for COVID-19. This is particularly true in the outpatient setting. Let’s count how many we have today, hmm, this shouldn’t take long. That would be zero —... read more

Artificial Intelligence in Telemetry: What Clinicians Should Know

Artificial Intelligence in Telemetry: What Clinicians Should Know

Advances in artificial intelligence are beginning to unlock the potential of telemetry data to directly inform diagnosis and personalized treatment. We can see hints of this in considering the case above. Is a second... read more

Epidemiology of Functional Seizures Among Adults Treated at a University Hospital

Epidemiology of Functional Seizures Among Adults Treated at a University Hospital

This case-control study found evidence to support previously reported associations, discovered new associations between functional seizures and PTSD, anxiety, and depression. An association between cerebrovascular disease... read more

Accuracy of Heparin-Binding Protein in Diagnosing Sepsis

Accuracy of Heparin-Binding Protein in Diagnosing Sepsis

The diagnostic ability of heparin-binding protein is favorable, demonstrating both high sensitivity and specificity in predicting progression to sepsis in critically ill patients. Future studies could assess the incremental... read more