Use of a Machine Learning Model to Predict Iatrogenic Hypoglycemia

Use of a Machine Learning Model to Predict Iatrogenic Hypoglycemia

These findings suggest that iatrogenic hypoglycemia can be predicted in a short-term prediction horizon after each BG measurement during hospitalization. Further studies are needed to translate this model into a real-time... read more

Management of late onset urea cycle disorders-a remaining challenge for the intensivist?

Management of late onset urea cycle disorders-a remaining challenge for the intensivist?

Awareness of urea cycle disorders in adults intensive care units can optimize early management and accordingly dramatically improve prognosis. By preventing hyperammonemia to induce brain edema and herniation leading to death. Hyperammonemia... read more

Ivermectin for COVID-19, Breakthrough Treatment or Hydroxychloroquine Redux?

Ivermectin for COVID-19, Breakthrough Treatment or Hydroxychloroquine Redux?

It’s an indisputable fact that we need better treatments for COVID-19. This is particularly true in the outpatient setting. Let’s count how many we have today, hmm, this shouldn’t take long. That would be zero —... read more

Artificial Intelligence in Telemetry: What Clinicians Should Know

Artificial Intelligence in Telemetry: What Clinicians Should Know

Advances in artificial intelligence are beginning to unlock the potential of telemetry data to directly inform diagnosis and personalized treatment. We can see hints of this in considering the case above. Is a second... read more

Epidemiology of Functional Seizures Among Adults Treated at a University Hospital

Epidemiology of Functional Seizures Among Adults Treated at a University Hospital

This case-control study found evidence to support previously reported associations, discovered new associations between functional seizures and PTSD, anxiety, and depression. An association between cerebrovascular disease... read more

Accuracy of Heparin-Binding Protein in Diagnosing Sepsis

Accuracy of Heparin-Binding Protein in Diagnosing Sepsis

The diagnostic ability of heparin-binding protein is favorable, demonstrating both high sensitivity and specificity in predicting progression to sepsis in critically ill patients. Future studies could assess the incremental... read more

It Is a Marathon, Not a Sprint – Sustainability of Stewardship in ICUs

It Is a Marathon, Not a Sprint – Sustainability of Stewardship in ICUs

ICUs are arguably the most important yet most challenging hospital environments for antimicrobial stewardship. The stakes are high with critically ill patients, where the burden of resistant Gram-negative pathogens is greater... read more

Acinetobacter Baumannii Native Valve Infective Endocarditis

Acinetobacter Baumannii Native Valve Infective Endocarditis

This report underlines the severe nature of A. baumannii infections, which are still associated with a prolonged hospital stay, and increased morbidity, mortality, and medical costs. Infective endocarditis caused by Acinetobacter... read more

Two-Step Imputation and AdaBoost-Based Classification for Early Prediction of Sepsis on Imbalanced Clinical Data

Two-Step Imputation and AdaBoost-Based Classification for Early Prediction of Sepsis on Imbalanced Clinical Data

Sepsis is a life-threatening response to infection that causes tissue damage, organ failure, and death. Effective early prediction of sepsis would improve patients’ diagnosis and reduce the cost associated with late-stage... read more

ED Evaluation and Management of Non-Obstetric Abdominal Pain in the Pregnant Patient

ED Evaluation and Management of Non-Obstetric Abdominal Pain in the Pregnant Patient

A 27-year-old G4P2 female at 25-weeks gestation presents to the emergency department with right upper quadrant abdominal pain. The pain began yesterday and was initially a generalized discomfort that localized to the right... read more

Experience Caring for a Severe COVID-19 Patient With ARDS in the ICU

Experience Caring for a Severe COVID-19 Patient With ARDS in the ICU

The author's experience caring for a patient with COVID-19 whose condition deteriorated rapidly into a critical illness in the negative pressure room of the ICU is described in this article. The onset of severe acute... read more

14-Day Occurrence of Hypoxia, ICU Admission, and Death Among Patients with COVID-19

14-Day Occurrence of Hypoxia, ICU Admission, and Death Among Patients with COVID-19

Uncertainty surrounding COVID-19 regarding rapid progression to acute respiratory distress syndrome (ARDS) and unusual clinical characteristics make discharge from a monitored setting challenging. Model derivation and... read more

Decompensated Hypothyroidism: Why do we miss it, and how do we improve?

Decompensated Hypothyroidism: Why do we miss it, and how do we improve?

A 75-year-old female is brought to the Emergency Department (ED) by emergency medical services (EMS) for altered mental status. Vital signs include BP 87/64, HR 55, T 92.6 rectal, RR 12, SpO2 95% on room air. She is oriented... read more

Panel Provides a Look at the Fast-changing Science of COVID-19 Diagnosis, Therapy, and Prevention

Panel Provides a Look at the Fast-changing Science of COVID-19 Diagnosis, Therapy, and Prevention

As the pace of research related to COVID-19 continues at an unprecedented rate, clinicians on the front line of the pandemic are challenged to keep up with a deluge of information to ensure they are bringing best practices... read more