Tag: drugs
Update: Implementation of Antibiotic Stewardship Core Elements
This document provides guidance on practical strategies to implement antibiotic stewardship programs in small and critical access hospitals. It was developed as a collaboration between The Centers for Disease Control and... read more
Ketamine: A Drug at War with Itself
KETAMINE has always been the odd one out. Like an eccentric uncle who always turns up at the holiday season with a new partner, ketamine has never really comfortably fitted in to simple classifications of anesthetic drugs.... read more
Four ways to reduce dangerous medical errors at your hospital
It's human nature, everyone makes mistakes. But the consequences of those mistakes can range wildly not only according to their severity, but also depending on who commits them. When a marketer makes a typo on a press release,... read more
Acetaminophen, Among Other Medications, Triggers Drug-Induced Liver Injury
More than 1,000 medications, with acetaminophen being the most common, have been associated with drug-induced liver injury (DILI). Diagnosis can be challenging due to the multitude of contributing factors, and timely recognition... read more
Sepsis Algorithm a Deadly Marker
An attempt by a Phoenix, AZ, hospital to develop a marker for deadly sepsis instead found that the algorithm identified patients at an increased risk of dying. Increasingly, algorithms govern daily life, playing an important... read more
Characterizing Hydrogels for use in drug delivery systems
The delivery of drugs to a precise location at the desired concentration without causing toxic effects to the rest of the body has been a challenge to biomedical science for many years. Although several approaches have been... read more
Alpha blockers more effective for large kidney stones
Researchers report a 57 percent higher risk of stone passage for larger stones with an alpha blocker, but no benefit for smaller stones. Location did not make a difference, nor did type of alpha blocker used.... read more
Drugs Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling
The researchers found that the drugs were well tolerated, with no serious adverse events reported. The indexed left ventricular end diastolic volume increased in patients treated with perindopril, bisoprolol, and placebo... read more
Value of Expedited Drug Approvals for Cancer Care
This study examines potential benefits of cancer drugs approved by the FDA on the basis of surrogate endpoints.... read more
Targeted Drug Delivery using Porous Glass Microspheres
Finding ways to improve efficiency and bioavailability is key to targeted drug delivery. Although controlled release dosage medication forms are the standard, they can have certain limitations.... read more
Study Examines Rates, Causes of ED Visits for Adverse Drug Events
The prevalence of emergency department (ED) visits for adverse drug events (ADEs) in the United States was estimated to be four per 1,000 individuals in 2013 and 2014, and the most common drug classes involved were anticoagulants,... read more
New Screening Test Identifies Potential Therapies to Fight Drug-Resistant Bacteria
Researchers at the NCATS and NIAID have found a new way to identify drugs and drug combinations that may potentially be useful in combating infections that are resistant to antibiotics. The researchers used the test to screen... read more
New discovery paves way for pancreatic cancer treatment
Patients suffering from pancreatic cancer may soon face better treatment options due to the latest discovery by Dr. Reginald Hill, who's research focuses on drugs that are already approved by the FDA.... read more
Baxter initiates late-stage study of novel therapy for acute kidney injury
Baxter International commences a Phase 3 clinical trial assessing an investigational drug, Prismocitrate 18, that combines a citrate anticoagulant and renal replacement solution.... read more
The 12 Most Important Health Innovations Of The Year
The best of what's new in health innovations this year.... read more
FDA Approves Zinplava to Reduce Recurrence of Clostridium difficile Infection in Adult Patients
FDA Approves Merck's ZINPLAVA (bezlotoxumab) to Reduce Recurrence of Clostridium difficile Infection (CDI) in Adult Patients Receiving Antibacterial Drug Treatment for CDI Who Are at High Risk of CDI Recurrence.... read more
Cefiderocol, A Novel Investigational Siderophore Cephalosporin, Demonstrated Potent Activity Against Multi-Drug Resistant Gram-Negative Pathogens
Cefiderocol showed potent activity against Gram-negative pathogens, including carbapenem-resistant strains of Pseudomonas aeruginosa and Acinetobacter baumannii as well as carbapenem-resistant Enterobacteriaceae. The results... read more