Tag: ECMO
High Risk of Thrombosis in Patients With Severe SARS-CoV-2 Infection
Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications. Higher anticoagulation targets than in usual critically ill patients should therefore... read more
From despair to hope: advanced therapy gives a lifeline to the sickest COVID-19 patients
More than two months later, that piece of paper still lies on her coffee table with four letters on it: "E-C-M-O." Irena Veronese had never heard that acronym before, but when it was first mentioned to her, it meant moving... read more
Clinical Experience of Whole-body CT as the Initial Evaluation Tool After ECPR in OHCA Patients
Routine whole-body computed tomography (CT) after extracorporeal cardiopulmonary resuscitation (ECPR) in out-of-hospital cardiac arrest (OHCA) patients appears to have a limited role, as the majority is caused by ACS. However,... read more
How I Approach Weaning from Venoarterial ECMO
Weaning from VA-ECMO remains a challenging but critically important step in device management. The key is to balance minimizing complications associated with device support with the potential for hemodynamic deterioration... read more
Spotting the Clotting: Hypercoagulopathy in COVID-19
Evolving experience with TEG, clotting parameters, treatment considerations, and ongoing data gathering will help us better understand if antiplatelet therapy with aspirin or clopidogrel or anticoagulant treatment with traditional... read more
Remdesivir 5-day vs. 10-day Trial Raises Some Red Flags?
Gilead's first Randomized Controlled Trial on remdesivir was just published, and it's very interesting. This is a trial designed, monitored, and written by Gilead. In some ways, the design of the trial and its missing parts... read more
Long-Term Health-Related Quality of Life After Venovenous Extracorporeal Membrane Oxygenation
This study examined the long-term health-related quality of life in adult patients treated with venovenous extracorporeal membrane oxygenation (V-V ECMO) for severe acute respiratory failure in Ireland. A retrospective, cross-sectional... read more
Unfractionated Heparin (UFH), LMWH, Fondaparinux, Argatroban, and Bivalirudin
Unfractionated heparin (UFH) binds to anti-thrombin III (AT-III), which enhances antithrombin's inhibition of several coagulation factors – especially factor Xa and factor IIa (thrombin). Low Molecular-Weight Heparin... read more
Sharing Data is the Key to Unlocking Remdesivir Challenges
Critical care teams should consider using remdesivir to treat patients with severe acute SARS-CoV-2 infection, but supply of the drug is limited and best practices for maximizing its effectiveness are not completely understood. The... read more
Global Effort to Collect Data on Ventilated Patients With COVID-19
As the new chair of the Asia-Pacific Chapter of the Extracorporeal Life Support Organization (ELSO), John Fraser, MBChB, PhD, began talking with the group's members last November about why influenza affects some people worse... read more
Nationwide System to Centralize Decisions Around ECMO Use for Severe COVID-19 Pneumonia in Japan
The novel coronavirus disease 2019 (COVID-19) is spreading in Japan. The number of patients who need extracorporeal membrane oxygenation (ECMO) is expected to increase; however, the clinical characteristics of the patients... read more
How I Manage Drainage Insufficiency on ECMO
As the use of extracorporeal membrane oxygenation (ECMO) expands, a systematic approach to the management of complex technical issues, such as drainage insufficiency, is essential to improving patient outcomes. Due to... read more
An Interview With an Italian Intensivist on the COVID Experience in Italy
The current COVID-19 crisis has a huge human impact. Clearly cardiovascular issues have a central role in management and, unfortunately, in adverse outcomes. We are continually struggling to understand risks and management... read more
ARDS Diagnosis May Be Underrecognized
The February 27, 2020 Department of Internal Medicine Medical Grand Rounds "Acute Respiratory Distress Syndrome (ARDS),” was presented by Marc Moss, MD, Roger S. Mitchell Professor of Medicine; head, Division of Pulmonary... read more
ECMO Support in Coronavirus Disease 2019 (COVID-19)
Extracorporeal membrane oxygenation (ECMO) use has been increasing in severe respiratory and/or cardiac failure despite implementation of conventional care. This technology has been proven valuable in treating viral pneumonia... read more
Multi-Modal Characterization of the Coagulopathy Associated With ECMO
The extracorporeal membrane oxygenation(ECMO)-associated coagulopathy is a multifactorial and quickly developing syndrome. It is characterized by individual changes of coagulation parameters and platelets and is aggravated... read more
Prone Positioning Monitored by Electrical Impedance Tomography in Patients with Severe ARDS on VV-ECMO
Prone positioning (PP) during veno-venous ECMO is feasible, but its physiological effects have never been thoroughly evaluated. Our objectives were to describe, through electrical impedance tomography (EIT), the impact of... read more
Impact of Levosimendan on Weaning from Peripheral VA-ECMO in ICU
This study suggests that levosimendan might be associated with a beneficial effect on venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in ICU patients. The difference in mortality among propensity-matched... read more
