The Reemergence of Ketamine for Treatment in Critically Ill Adults

Ketamine has suggested potential benefit in several disease states impacting critically ill patients including pain, alcohol withdrawal syndrome, status epilepticus, and acute agitation. Further supporting evidence is needed... read more

The Reemergence of Ketamine for Treatment in Critically Ill Adults

ERC-ESICM Guidelines on Temperature Control After Cardiac Arrest in Adults

The aim of these guidelines is to provide evidence‑based guidance for temperature control in adults who are comatose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying... read more

ERC-ESICM Guidelines on Temperature Control After Cardiac Arrest in Adults

New Resuscitation Guidance for Patients with COVID-19

In response to the COVID-19 pandemic, the American Heart Association and collaborating organizations, including the American Academy of Pediatrics, the American Association for Respiratory Care, the Society of Critical Care... read more

New Resuscitation Guidance for Patients with COVID-19

Transtracheal Jet Ventilation in the Can’t Intubate Can’t Oxygenate Emergency

Transtracheal jet ventilation (TTJV) is associated with a high risk of device failure and barotrauma in the CICO emergency. Guidelines and recommendations supporting the use of TTJV in CICO should be reconsidered. 44 studies... read more

Transtracheal Jet Ventilation in the Can’t Intubate Can’t Oxygenate Emergency

COVID-19 Guidance for Hospital Reporting and FAQs

Hospitals are responsible for reporting the information to the Federal government. Facilities should report at the individual hospital level, even if hospitals share a Centers for Medicare & Medicaid Services (CMS) Certification... read more

COVID-19 Guidance for Hospital Reporting and FAQs

Consensus Process to Define Guiding Principles for Acute Perioperative Pain Management

The US Health and Human Services Pain Management Best Practices Inter-Agency Task Force initiated a public–private partnership which led to the publication of its report in 2019. The report emphasized the need for individualized,... read more

Consensus Process to Define Guiding Principles for Acute Perioperative Pain Management

ECMO in Children Receiving HCT and Immune Effector Cell Therapy

Use of extracorporeal membrane oxygenation (ECMO) in children receiving hematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable... read more

ECMO in Children Receiving HCT and Immune Effector Cell Therapy

Loading and Increasing Vancomycin Dose Frequency Not Advantageous for Gram-Positive Sepsis in Infants

The efficacy of a vancomycin loading dose with more frequent dosing and shorter duration of treatment was comparable to standard dosing regimens for gram-positive sepsis in infants but with heightened risk for impaired hearing,... read more

Loading and Increasing Vancomycin Dose Frequency Not Advantageous for Gram-Positive Sepsis in Infants

Inhaled Amphotericin B Lipid Complex for Prophylaxis Against COVID-19-associated Invasive Pulmonary Aspergillosis

Recently, Prattes and colleagues published in Intensive Care Medicine a high incidence of coronavirus disease 2019-associated invasive pulmonary aspergillosis (CAPA), according to 2020 ECMM/ISHAM consensus criteria, with... read more

Inhaled Amphotericin B Lipid Complex for Prophylaxis Against COVID-19-associated Invasive Pulmonary Aspergillosis

High-dose vs. Low-dose Prednisolone in post-COVID-19 Patients

In some patients, respiratory symptoms and imaging abnormalities persist after acute coronavirus disease 2019 (COVID-19) pneumonia. The chest computed tomography (CT) generally shows diffuse parenchymal lung abnormalities... read more

High-dose vs. Low-dose Prednisolone in post-COVID-19 Patients

Recovery, Rehabilitation and Follow-up Services After Critical Illness

Overall, these data demonstrate a proliferation of recovery, follow-up and rehabilitation services for critically ill adults in the past decade across the UK, although service gaps remain suggesting further work is required... read more

Recovery, Rehabilitation and Follow-up Services After Critical Illness

WHO Issues Guidelines on the Treatment of Children with MIS Associated with COVID-19

WHO issued updated guidelines on the management of multisystem inflammatory syndrome (MIS) in children associated with COVID-19 (MIS-C). MIS-C is a rare but serious condition where children with COVID-19 develop inflammation... read more

WHO Issues Guidelines on the Treatment of Children with MIS Associated with COVID-19

Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management

Evidence supports the use of ketamine for acute pain in a variety of contexts, including as a stand-alone treatment, as an adjunct to opioids, and, to a lesser extent, as an intranasal formulation. Contraindications for... read more

Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management

NIH-convened Expert Panel Proposes Standardized Definition of Placental COVID-19 Infection

A panel of experts convened by the National Institutes of Health has recommended standardized criteria to define infection of the placenta with SARS-CoV-2, the virus that causes COVID-19. The panel also offers guidance... read more

NIH-convened Expert Panel Proposes Standardized Definition of Placental COVID-19 Infection

Percutaneous Dilational Tracheostomy for COVID-19 Patients Requiring Mechanical Ventilation

Patients with COVID-19 who survive the early days of MV experience severe and prolonged respiratory failure. An early modified percutaneous dilational tracheostomy (PDT) was safe for patients and healthcare providers and... read more

Percutaneous Dilational Tracheostomy for COVID-19 Patients Requiring Mechanical Ventilation

How I Went from Pulmonary Diagnostics and Wellness to System Lung Coordinator

Main Line Health is a multi-hospital health system serving patients in Philadelphia, PA, and its western suburbs. The system has been recognized as among the best in the region by U.S. News & World Report. In 2017, it was... read more

How I Went from Pulmonary Diagnostics and Wellness to System Lung Coordinator

Criteria for Selecting COVID-19 Patients for Lung Transplantation

In May 2020, a team led by thoracic surgeon Konrad Hoetzenecker of the Department of Surgery of MedUni Vienna and Vienna General Hospital performed a lung transplant on a 44-year-old patient who had been seriously ill with... read more

Criteria for Selecting COVID-19 Patients for Lung Transplantation

Guidance on COVID-19 Clinical Care and Treatment by Specialty

We are providing these links as part of our support to members seeking specialty advice for specific medical conditions, particularly those outside their own specialty. The situation is a fast-evolving one, and while we will... read more

Guidance on COVID-19 Clinical Care and Treatment by Specialty

Promoting Evidence-Based Practice in ARDS

There is a dearth of literature addressing interventions to improve implementation of evidence-based practices in acute respiratory distress syndrome (ARDS). Existing interventions to improve clinician knowledge and facilitate... read more

Promoting Evidence-Based Practice in ARDS

Addressing Hospital-Acquired Hypoglycemia

Findings suggest that ensuring a consistent 30-minute window between POC BG measurement and meal delivery enabled nursing staff to perform timely POC BG measurements and administer a more optimal mealtime insulin dose. Increasing... read more

Addressing Hospital-Acquired Hypoglycemia

Validation of Sputum Gram Stain for Treatment of CAP and HCAP

The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia... read more

Validation of Sputum Gram Stain for Treatment of CAP and HCAP