Vasopressin for Acute Hemorrhage?

Vasopressin for Acute Hemorrhage?

Vasoactive medications are one of the pillars of management of shock in Emergency Departments. Inopressors, namely Norepinephrine and Epinephrine, are the two most commonly used pressors in US Emergency Departments, used... read more

Predicting Adverse Hemodynamic Events in Critically Ill Patients

Predicting Adverse Hemodynamic Events in Critically Ill Patients

The art of predicting future hemodynamic instability in the critically ill has rapidly become a science with the advent of advanced analytical processed based on computer-driven machine learning techniques. How these... read more

The Neurohormonal Basis of Pulmonary Hypertension in HFpEF

The Neurohormonal Basis of Pulmonary Hypertension in HFpEF

Subjects with heart failure with preserved ejection fraction (HFpEF) display activation of the endothelin and adrenomedullin neurohormonal pathways, the magnitude of which is associated with pulmonary hemodynamic derangements,... read more

Nonoperative Management of Splenic Injury of Patients with Reduced Consciousness is Safe and Feasible in Well-equipped Institutions

Nonoperative Management of Splenic Injury of Patients with Reduced Consciousness is Safe and Feasible in Well-equipped Institutions

This study shows that NOM for blunt splenic trauma is a viable treatment modality in well-equipped institutions, regardless of the patients mental status. However, the presence of neurologic impairment is associated with... read more

Ultrasound-based Clinical Profiles for Predicting the Risk of Intradialytic Hypotension in Critically Ill Patients on Intermittent Dialysis

Ultrasound-based Clinical Profiles for Predicting the Risk of Intradialytic Hypotension in Critically Ill Patients on Intermittent Dialysis

In critically ill patients on intermittent hemodialysis, the absence of hypervolemia as assessed by lung and vena cava ultrasound predisposes to intradialytic hypotension and suggests alternative techniques of hemodialysis... read more

Adaptive Mechanical Ventilation with Automated Minimization of Mechanical Power

Adaptive Mechanical Ventilation with Automated Minimization of Mechanical Power

Adaptive mechanical ventilation with automated minimization of inspiratory power may lead to more lung-protective ventilator settings when compared with adaptive mechanical ventilation according to Otis' equation. Comparing... read more

Pulmonary Artery Catheters for Adult Patients in ICU

Pulmonary Artery Catheters for Adult Patients in ICU

Pulmonary Artery Catheters (PAC) is a diagnostic and haemodynamic monitoring tool but not a therapeutic intervention. Our review concluded that use of a PAC did not alter the mortality, general ICU or hospital LOS, or cost... read more

Practical Trends in Anesthesia and Intensive Care 2018

Practical Trends in Anesthesia and Intensive Care 2018

This book offers an essential guide to managing the most-debated hot topics of practical interest in anesthesia and intensive care. It reviews the state of the art in issues concerning both intensive care medicine and anesthesia,... read more

Using Additional Pressure Control Lines When Connecting a Continuous RRT Device to an ECMO Circuit

Using Additional Pressure Control Lines When Connecting a Continuous RRT Device to an ECMO Circuit

The present study suggests that the use of additional tubing can be considered a simple and safe method for pressure control and improvement of filter survival when connecting a continuous renal replacement therapy (CRRT)... read more

Snapshots of Hemodynamics

Snapshots of Hemodynamics

This new edition reviews recent developments in genetics and molecular biology and new noninvasive measurement techniques that have enabled vast improvements in the measurement and understanding of cardiovascular hemodynamics.... read more

Echocardiographic Assessment of Pulmonary Artery Occlusion Pressure in Ventilated Patients

Echocardiographic Assessment of Pulmonary Artery Occlusion Pressure in Ventilated Patients

TEE accurately predicts invasive PAOP ≤ 18 mmHg in ventilated patients. This further increases its diagnostic value in patients with suspected acute lung injury/acute respiratory distress syndrome. During two consecutive... read more

Mobilization Practices for Patients with Burn Injury in Critical Care

Mobilization Practices for Patients with Burn Injury in Critical Care

Mobilization therapy of patients with burns in the ICU was characterized by a low mobility level during mechanical ventilation with a low functional status at hospital discharge. Of the 74 patients admitted, 66% were placed... read more

Vasoactive Medication and Randomized Clinical Trials

Vasoactive Medication and Randomized Clinical Trials

Vasoactive medication is one of the cornerstones in the treatment of critically ill patients in shock. Shock can be defined as a failure of the circulatory system to provide adequate tissue perfusion resulting in cellular... read more

Refractory Septic Shock: Our Pragmatic Approach

Refractory Septic Shock: Our Pragmatic Approach

Despite timely intervention, there exists a small subgroup of patients with septic shock who develop progressive multi-organ failure. Seemingly refractory to conventional therapy, they exhibit a very high mortality. Such... read more

Cardiovascular Dynamics in Critically Ill Patients

Cardiovascular Dynamics in Critically Ill Patients

Although widely used among physicians and frequently present in the literature, the words "stable" and "unstable" to describe cardiovascular dynamics in critically ill patients can have different meanings to different people... read more

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

Transfusion of red blood cells is an everyday practice in critical care with the primary aim of restoring adequate tissue oxygenation. However, blood transfusion may also be harmful and costly, therefore a so called restrictive... read more

Extubating Ventilated Patients on Vasoactive Infusions is Safe

Extubating Ventilated Patients on Vasoactive Infusions is Safe

In a large single centre study, 21% of intubated patients who received infusions of vasoactive infusions while mechanically ventilated were extubated for the first time while still receiving them. Coincident with their earlier... read more