Conservative or Liberal Oxygen Targets in Patients on VA-ECMO

In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more

Hyperoxemia in Acute Trauma is Common and Associated with a Longer Hospital Stay

This study indicate that hyperoxemia is not associated with increased 28-day mortality compared to normoxemia. Nonetheless, both moderate and severe hyperoxemia are frequently detected in trauma patients, with severe hyperoxemia... read more

Closed-loop oxygen control improves oxygen therapy in AHRF patients under high flow nasal oxygen

Closed-loop oxygen control improves oxygen therapy in AHRF patients under high flow nasal oxygen

Closed-loop oxygen control improves oxygen administration in patients with moderate-to-severe AHRF treated with HFNO, increasing the percentage of time in the optimal oxygenation range and decreasing the workload of healthcare... read more

Conservative or Liberal Oxygen Therapy in Adults After Cardiac Arrest

Conservative or Liberal Oxygen Therapy in Adults After Cardiac Arrest

Conservative oxygen therapy was associated with a statistically significant reduction in mortality at last follow-up compared to liberal oxygen therapy but the certainty of available evidence was low or very low due to bias,... read more

Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a PICU

Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a PICU

Greater numbers of severe hyperoxemia events appeared to be associated with increased mortality in this large, diverse cohort of critically ill children, supporting a possible exposure-response association between severe... read more

Oxygen Therapy in Acute Resuscitation

Oxygen Therapy in Acute Resuscitation

At present, evidence is lacking to support routine liberal oxygen administration in acutely ill patients and, in most circumstances, a reasonable approach is to titrate supplemental oxygen to achieve an arterial oxygen saturation... read more

Partial Pressure of Oxygen and Neurological Outcome in Out-of-Hospital Cardiac Arrest Patients

Partial Pressure of Oxygen and Neurological Outcome in Out-of-Hospital Cardiac Arrest Patients

Following out-of-hospital cardiac arrest (OHCA), patients regularly suffer from post cardiac arrest syndrome including symptoms of anoxic brain injury and reperfusion-related damage. Hyperoxemia or hypoxemia exposure occurred... read more