Tag: ICP
Balancing the Breath: Navigating the Brain-Lung Connection in Acute Brain Injury
This study explores the delicate tug-of-war between mechanical ventilation (MV) and outcomes for patients with Acute Brain Injury (ABI). The researchers highlight that the way we breathe for a patient can significantly influence... read more
REGULATE Trial: Norepinephrine vs. Vasopressin – The Head-to-Heart Showdown in Severe TBI
REGULATE is the first adequately powered trial to systematically compare these vasopressor strategies in severe TBI. The results are expected to provide an evidence-based foundation for developing individualized vasopressor... read more
Individualizing PEEP in Acute Brain Injury
The consensus is that Positive End-Expiratory Pressure (PEEP) can be safely used in most patients with Acute Brain Injury (ABI), provided its effects on the brain are closely monitored. PEEP Safety and ICP: While PEEP... read more
Impact of Low-Dose Ketamine Infusion on Intracranial Pressure and Hemodynamics in Septic Shock Patients
Adult patients with septic shock, on hemodynamic support, had high-to-normal intracranial pressure (ICP). Low-dose continuous ketamine infusion as an adjunct sedative appeared to have favorable outcomes concerning ICP and... read more
Critical Care Device Series: External Ventricular Drain
External ventricular drainage (EVD), is one of the most frequently performed neurosurgical procedures, with approximately 20,000 performed annually. EVD placement is often considered a lifesaving measure to alleviate severe... read more
Acute Effects of Ketamine on ICP in Children With Severe TBI
In this retrospective, exploratory study, intracranial pressure (ICP) did not increase following ketamine administration. In the setting of a guidelines-based protocol, ketamine was associated with a reduction in ICP during... read more
Cerebral Hypoperfusion Detection with Dynamic Hyperoxia Test
In a heterogeneous population of acute brain-injured patients, cerebral multimodal monitoring with intracranial pressure (ICP) and brain tissue oxygen pressure (PbtO2) detected regional cerebral hypoperfusion with a higher... read more
ICP Monitoring in Patients with Acute Brain Injury
The use of intracranial pressure (ICP) monitoring and ICP management varies greatly across centres and countries. The use of ICP monitoring might be associated with a more intensive therapeutic approach and with lower 6-month... read more
Patient’s Clinical Presentation and CPPopt Availability: Any Association?
In this retrospective multicenter study, none of the selected admission and treatment variables were related to the CPPopt yield. The median CPPopt yield was 80.7% (interquartile range 70.9–87.4%). None of the selected... read more
Fully Automated, Real-time, Calibration-free, Continuous Noninvasive Estimation of Intracranial Pressure in Children
This nICP estimation algorithm, based on arterial blood pressure (ABP) and bedside transcranial Doppler (TCD) cerebral blood flow velocity (CBFV) waveform measurements, performs in a manner comparable to invasive intracranial... read more
Guidelines for the Management of Pediatric Severe Traumatic Brain Injury
Update of the Brain Trauma Foundation Guidelines, Third Edition. Severe Traumatic Brain Injury in Infants, Children, and Adolescents in 2019: Some Overdue Progress, Many Remaining Questions, and Exciting Ongoing Work in the... read more
Ultrasound Non-invasive Measurement of Intracranial Pressure in Neurointensive Care
Of the studied ultrasound nICP methods, ONSD is the best estimator of Intracranial Pressure (ICP). The novel combination of ONSD ultrasonography and vTCD of the straight sinus is a promising and easily available technique... read more
Consideration of the Intracranial Pressure Threshold Value for the Initiation of TBI Treatment
Monitoring of intracranial pressure (ICP) is considered to be fundamental for the care of patients with severe traumatic brain injury (TBI) and is routinely used to direct medical and surgical therapy. The cerebral circulation... read more
